Search Results - "SATOH, Takashi"
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1
The role of HMGB1 in inflammatory skin diseases
Published in Journal of dermatological science (01-08-2022)Get full text
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2
Toll-Like Receptor Signaling and Its Inducible Proteins
Published in Microbiology spectrum (23-12-2016)“…Studies that bridge innate immunity and various diseases are making rapid advances. Macrophages and dendritic cells play a leading role in innate immunity,…”
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3
Structure and variation of the mitochondrial genome of fishes
Published in BMC genomics (07-09-2016)“…The mitochondrial (mt) genome has been used as an effective tool for phylogenetic and population genetic analyses in vertebrates. However, the structure and…”
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4
Genetic mutations in pyoderma gangrenosum, hidradenitis suppurativa, and associated autoinflammatory syndromes: Insights into pathogenic mechanisms and shared pathways
Published in Journal of dermatology (01-02-2024)“…Pyoderma gangrenosum (PG), hidradenitis suppurativa (HS), and the associated autoinflammatory syndromes, including pyogenic arthritis, pyoderma gangrenosum,…”
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5
Therapeutic potential of targeting interleukin‐1 family cytokines in chronic inflammatory skin diseases
Published in British journal of dermatology (1951) (01-06-2022)“…Summary The interleukin (IL)‐1 family of cytokines is a central regulator of a myriad of immunological responses. It comprises several cytokines, including…”
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Evolutionary origin of the Scombridae (tunas and mackerels): members of a paleogene adaptive radiation with 14 other pelagic fish families
Published in PloS one (04-09-2013)“…Uncertainties surrounding the evolutionary origin of the epipelagic fish family Scombridae (tunas and mackerels) are symptomatic of the difficulties in…”
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Mothocya kaorui n. sp. (Crustacea: Isopoda: Cymothoidae), a fish-parasitic isopod with unique antennules from the Izu Islands, Japan
Published in Systematic parasitology (01-06-2023)“…A new species of fish-parasitic isopod in the family Cymothoidae is described from the Izu Islands, Japan. Mothocya kaorui n. sp. is reported from the gill…”
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8
Identification of an atypical monocyte and committed progenitor involved in fibrosis
Published in Nature (London) (05-01-2017)“…An atypical monocyte with partial granulocyte characteristics is identified and shown to be critical for the development of fibrosis. An immunological cell…”
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9
Regnase-1, an Immunomodulator, Limits the IL-36/IL-36R Autostimulatory Loop in Keratinocytes to Suppress Skin Inflammation
Published in Journal of investigative dermatology (01-06-2018)Get full text
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10
MitoFish and MitoAnnotator: a mitochondrial genome database of fish with an accurate and automatic annotation pipeline
Published in Molecular biology and evolution (01-11-2013)“…Mitofish is a database of fish mitochondrial genomes (mitogenomes) that includes powerful and precise de novo annotations for mitogenome sequences. Fish occupy…”
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11
Pivotal role of RNA-binding E3 ubiquitin ligase MEX3C in RIG-I–mediated antiviral innate immunity
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-2014)“…The RIG-I–like receptors, retinoic acid inducible gene-1 (RIG-I), melanoma differentiation-associated protein 5, and laboratory of genetics and physiology-2,…”
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12
H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma
Published in Cancer research (Chicago, Ill.) (15-12-2017)“…Activation of the fibroblast growth factor receptor FGFR4 by FGF19 drives hepatocellular carcinoma (HCC), a disease with few, if any, effective treatment…”
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13
Role of the NLRP1 inflammasome in skin cancer and inflammatory skin diseases
Published in British journal of dermatology (1951) (16-02-2024)“…Inflammasomes are cytoplasmic protein complexes that play a crucial role in protecting the host against pathogenic and sterile stressors by initiating…”
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14
LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
Published in Proceedings of the National Academy of Sciences - PNAS (26-01-2010)“…RNA virus infection is recognized by retinoic acid-inducible gene (RIG)-I-like receptors (RLRs), RIG-I, and melanoma differentiation-associated gene 5 (MDA5)…”
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15
CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17–Mediated Psoriasiform Skin Inflammation In Vivo
Published in Journal of investigative dermatology (01-09-2018)“…Rare autosomal dominant mutations in the gene encoding the keratinocyte signaling molecule CARD14, have been associated with an increased susceptibility to…”
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Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice
Published in PLoS genetics (01-06-2022)“…Meiosis is a hallmark event in germ cell development that accompanies sequential events executed by numerous molecules. Therefore, characterization of these…”
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Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response
Published in The Journal of experimental medicine (03-06-2019)“…Regnase-1 (also known as Zc3h12a or MCPIP-1) is an endoribonuclease involved in mRNA degradation of inflammation-associated genes. Regnase-1 is inactivated in…”
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The Jmjd3- Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
Published in Nature immunology (01-10-2010)“…Macrophages can be divided into two subsets, M1 and M2, which have crucial differences in their function. Akira and colleagues identify the histone demethylase…”
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Critical role of Trib1 in differentiation of tissue-resident M2-like macrophages
Published in Nature (London) (28-03-2013)“…Haematopoietic expression of the adaptor protein Trib1 is shown to be required for the presence of adipose-tissue-resident macrophages with an M2-like…”
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Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
Published in Proceedings of the National Academy of Sciences - PNAS (08-12-2009)“…Microbial nucleic acids are critical for the induction of innate immune responses, a host defense mechanism against infection by microbes. Recent studies have…”
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