Search Results - "SATO, Keizo"
-
1
Direct detection of diclofenac radical produced by ultraviolet irradiation using electron spin resonance method
Published in Journal of Clinical Biochemistry and Nutrition (2020)“…Diclofenac, a nonsteroidal anti-inflammatory drug, is commonly used as an antipyretic analgesic owing to its strong anti-inflammatory action in clinical…”
Get full text
Journal Article -
2
Low Back Pain Exacerbation Is Predictable Through Motif Identification in Center of Pressure Time Series Recorded During Dynamic Sitting
Published in Frontiers in physiology (14-09-2021)“…Background: Low back pain (LBP) is a common health problem — sitting on a chair for a prolonged time is considered a significant risk factor. Furthermore, the…”
Get full text
Journal Article -
3
Hemodialysis raises oxidative stress through carbon-centered radicals despite improved biocompatibility
Published in Journal of Clinical Biochemistry and Nutrition (2021)“…Leukocyte activation and the resulting oxidative stress induced by bioincompatible materials during hemodialysis impact the prognosis of patients. Despite…”
Get full text
Journal Article -
4
Impact of green tea intake on the pharmacokinetics of celiprolol in healthy subjects
Published in International journal of clinical pharmacology and therapeutics (01-03-2021)“…To assess the effect of green tea intake on the pharmacokinetics of the β-blocker celiprolol. In an open-label crossover study, 3 healthy subjects were given…”
Get full text
Journal Article -
5
Effects of Lecithinized Superoxide Dismutase and/or Pirfenidone Against Bleomycin-Induced Pulmonary Fibrosis
Published in Chest (01-10-2012)“…Background Idiopathic pulmonary fibrosis (IPF) involves lung injury induced by reactive oxygen species (ROS), such as superoxide anion, and fibrosis…”
Get full text
Journal Article -
6
Dose-dependent decrease in anti-oxidant capacity of whole blood after irradiation: A novel potential marker for biodosimetry
Published in Scientific reports (09-05-2018)“…Many reports have demonstrated that radiation stimulates reactive oxygen species (ROS) production by mitochondria for a few hours to a few days after…”
Get full text
Journal Article -
7
Direct Radical Scavenging Activity of Benzbromarone Provides Beneficial Antioxidant Properties for Hyperuricemia Treatment
Published in Biological & pharmaceutical bulletin (01-03-2015)“…Uric acid exerts an important antioxidant effect against external oxidative stress under physiological conditions. However, uric acid itself can increase…”
Get full text
Journal Article -
8
Quantitative determination of phenothiazine derivatives in human plasma using monolithic silica solid-phase extraction tips and gas chromatography–mass spectrometry
Published in Journal of Chromatography A (06-05-2011)“…Solid-phase extraction (SPE) using micropipette tips is a useful technique to prepare samples prior to mass spectrometry. However, most commercial SPE tips…”
Get full text
Journal Article -
9
Positive Role of CCAAT/Enhancer-Binding Protein Homologous Protein, a Transcription Factor Involved in the Endoplasmic Reticulum Stress Response in the Development of Colitis
Published in The American journal of pathology (01-05-2009)“…Although recent reports suggest that the endoplasmic reticulum (ER) stress response is induced in association with the development of inflammatory bowel…”
Get full text
Journal Article -
10
Pleiotropic Effects of Levofloxacin, Fluoroquinolone Antibiotics, against Influenza Virus-Induced Lung Injury
Published in PloS one (18-06-2015)“…Reactive oxygen species (ROS) and nitric oxide (NO) are major pathogenic molecules produced during viral lung infections, including influenza. While…”
Get full text
Journal Article -
11
High-throughput determination of nonsteroidal anti-inflammatory drugs in human plasma by HILIC-MS/MS
Published in Journal of pharmaceutical and biomedical analysis (01-01-2014)“…•A HILIC-MS/MS method was developed for analysis of thirteen NSAIDs.•Only 20μL plasma was required in the assay.•The present study provided short analysis time…”
Get full text
Journal Article -
12
A new method for high-resolution and high-precision analysis of flunitrazepam and 7-aminoflunitrazepam in human body fluids using a Monolithic SPE SpinTip and UPLC–Q-ToF–MS
Published in Forensic toxicology (01-07-2019)“…Purpose Forensic toxicological analyses of drugs and their metabolites in human specimens usually require extractive pretreatment for successful analysis of…”
Get full text
Journal Article -
13
Lipopolysaccharide Decreases Single Immunoglobulin Interleukin-1 Receptor-related Molecule (SIGIRR) Expression by Suppressing Specificity Protein 1 (Sp1) via the Toll-like Receptor 4 (TLR4)-p38 Pathway in Monocytes and Neutrophils
Published in The Journal of biological chemistry (27-06-2014)“…Single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) is one of the immunoglobulin-like membrane proteins that is crucial for negative…”
Get full text
Journal Article -
14
Orally Administered Mucolytic Drug l-Carbocisteine Inhibits Angiogenesis and Tumor Growth in Mice
Published in The Journal of pharmacology and experimental therapeutics (01-09-2015)“…Angiogenesis, the formation of new blood vessels from pre-existing vessels, is essential for the growth and metastasis of tumors. In this study, we found that…”
Get more information
Journal Article -
15
An unusual case of fatal hypothermia involving topical diphenhydramine
Published in Forensic toxicology (2023)“…Purpose Diphenhydramine is an antihistamine drug widely used to alleviate symptoms caused by allergies and the common cold. Diphenhydramine-involved fatalities…”
Get full text
Journal Article -
16
Superiority of PC-SOD to other anti-COPD drugs for elastase-induced emphysema and alteration in lung mechanics and respiratory function in mice
Published in American journal of physiology. Lung cellular and molecular physiology (15-06-2012)“…Bronchodilators (such as ipratropium bromide), steroids (such as fluticasone propionate), and newly developed anti-inflammatory drugs (such as roflumilast) are…”
Get more information
Journal Article -
17
High-throughput determination of valproate in human samples by modified QuEChERS extraction and GC-MS/MS
Published in Legal medicine (Tokyo, Japan) (01-03-2018)“…•A new high-throughput determination of valproate.•A modified QuEChERS extraction was applied in the assay.•The present study provided the high sensitivity…”
Get full text
Journal Article -
18
Therapeutic effect of lecithinized superoxide dismutase against colitis
Published in The Journal of pharmacology and experimental therapeutics (01-01-2009)“…Ulcerative colitis (UC) involves intestinal mucosal damage induced by reactive oxygen species (ROS), in particular, superoxide anion. Superoxide dismutase…”
Get more information
Journal Article -
19
Mepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
Published in Nature communications (05-11-2013)“…The clinical treatment of chronic obstructive pulmonary disease (COPD) requires not only an improvement of airflow by bronchodilation but also the suppression…”
Get full text
Journal Article -
20
Prevention of UVB Radiation-induced Epidermal Damage by Expression of Heat Shock Protein 70
Published in The Journal of biological chemistry (19-02-2010)“…Irradiation with UV light, especially UVB, causes epidermal damage via the induction of apoptosis, inflammatory responses, and DNA damage. Various stressors,…”
Get full text
Journal Article