Search Results - "SATO, Atsuhisa"

Does the temporary decrease in the estimated glomerular filtration rate (eGFR) after initiation of mineralocorticoid receptor (MR) antagonist treatment lead to a long-term renal protective effect? by Sato, Atsuhisa

“…Recently, deleterious effects of aldosterone on the kidney via mineralocorticoid receptors (MRs) have been noted. MR antagonists have been reported to show…”
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The necessity and effectiveness of mineralocorticoid receptor antagonist in the treatment of diabetic nephropathy by Sato, Atsuhisa

“…Diabetes mellitus is a major cause of chronic kidney disease (CKD), and diabetic nephropathy is the most common primary disease necessitating dialysis…”
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Clinical effect of nonsteroidal mineralocorticoid receptor (MR) antagonists in the treatment of diabetic kidney disease: expectations as a new therapeutic strategy by Sato, Atsuhisa, Nishimoto, Mitsuhiro

“…Diabetes mellitus is the main cause of chronic kidney disease (CKD) in Japan and worldwide. Although angiotensin-converting enzyme (ACE) inhibitors and…”
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Mineralocorticoid receptor antagonists: their use and differentiation in Japan by Sato, Atsuhisa

“…In the presence of salt, aldosterone causes hypertension and organ damage via the mineralocorticoid receptor (MR) through various mechanisms. MR antagonists…”
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Effect of aldosterone breakthrough on albuminuria during treatment with a direct renin inhibitor and combined effect with a mineralocorticoid receptor antagonist by Sato, Atsuhisa, Fukuda, Seiichi

“…We have reported observing aldosterone breakthrough in the course of relatively long-term treatment with renin-angiotensin (RA) system inhibitors, where the…”
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Aldosterone-Induced Organ Damage: Plasma Aldosterone Level and Inappropriate Salt Status by SATO, Atsuhisa, SARUTA, Takao

“…In recent years, it has been clarified that aldosterone can directly damage various organs, such as the heart, blood vessel, and kidneys, via non-epithelial…”
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Methylation pattern of urinary DNA as a marker of kidney function decline in diabetes by Marumo, Takeshi, Hoshino, Junichi, Kawarazaki, Wakako, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Hirohama, Daigoro, Yamanouchi, Masayuki, Ubara, Yoshifumi, Okaneya, Toshikazu, Fujii, Takeshi, Yuki, Kazunari, Atsumi, Yoshihito, Sato, Atsuhisa, Arai, Eri, Kanai, Yae, Shimosawa, Tatsuo, Fujita, Toshiro

“…IntroductionRenal tubular injury contributes to the decline in kidney function in patients with diabetes. Cell type-specific DNA methylation patterns have been…”
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Combination Therapy with Aldosterone Blockade and Renin-Angiotensin Inhibitors Confers Organ Protection by Sato, Atsuhisa, Saruta, Takao, Funder, John W

“…There is increasing evidence that aldosterone exerts major adverse cardiovascular effects through classical mineralocorticoid receptors (MR) in nonepithelial…”
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Aldosterone Breakthrough During Angiotensin II Receptor Antagonist Therapy in Stroke-Prone Spontaneously Hypertensive Rats by Naruse, Mitsuhide, Tanabe, Akiyo, Sato, Atsuhisa, Takagi, Sachiko, Tsuchiya, Ken, Imaki, Toshihiro, Takano, Kazue

“…Aldosterone breakthrough during ACE inhibitor therapy has been reported. This study investigates changes in plasma aldosterone concentration (PAC) and its…”
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Relative Long-Term Effects of Spironolactone in Conjunction with an Angiotensin-Converting Enzyme Inhibitor on Left Ventricular Mass and Diastolic Function in Patients with Essential Hypertension by SATO, Atsuhisa, HAYASHI, Matsuhiko, SARUTA, Takao

“…It has been reported that treatment with an angiotensin-converting enzyme (ACE) inhibitor is not adequate to suppress aldosterone, and we previously…”
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Mumps virus-associated hemophagocytic syndrome by Hiraiwa, Kunihiko, Obara, Katsuyuki, Sato, Atsuhisa

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A prospective study of frequency and characteristics of cough during ACE inhibitor treatment by Sato, Atsuhisa, Fukuda, Seiichi

“…Angiotensin converting enzyme (ACE) inhibitors are reportedly effective, and positively indicated in patients with chronic heart failure with decreased…”
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Effects of Spironolactone and Angiotensin-Converting Enzyme Inhibitor on Left Ventricular Hypertrophy In Patients with Essential Hypertension by Sato, Atsuhisa, Suzuki, Yoshiyuki, Saruta, Takao

“…There is increasing evidence for important cardiovascular effects of aldosterone via classical mineralocorticoid receptors in the heart. Administration of…”
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High Serum Level of Procollagen Type III Amino-Terminal Peptide Contributes to the Efficacy of Spironolactone and Angiotensin-Converting Enzyme Inhibitor Therapy on Left Ventricular Hypertrophy in Essential Hypertensive Patients by SATO, Atsuhisa, TAKANE, Hiroshi, SARUTA, Takao

“…We recently demonstrated that spironolactone may have beneficial effects on left ventricular hypertrophy in selected patients with essential hypertension…”
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Effects of the angiotensin II type 1 receptor antagonist candesartan, compared with angiotensin-converting enzyme inhibitors, on the urinary excretion of albumin and type IV collagen in patients with diabetic nephropathy by Sato, Atsuhisa, Tabata, Mitsuhisa, Hayashi, Koichi, Saruta, Takao

“…We previously reported that the angiotensin II type 1 receptor antagonist candesartan was effective in reducing blood pressure and microalbuminuria in…”
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Adrenomedullin Stimulates cAMP Accumulation and Inhibits Atrial Natriuretic Peptide Gene Expression in Cardiomyocytes by Sato, Atsuhisa, Canny, Benedict J., Autelitano, Dominic J.

“…Adrenomedullin (ADM) is a novel vasodilating and natriuretic peptide which may play an important role in cardiovascular regulation. In neonatal cardiomyocyte…”
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Cardiovascular action of steroid hormones by Sato, Atsuhisa, Nishimoto, Mistuhisa

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Aldosterone antagonist facilitates the cardioprotective effects of angiotensin receptor blockers in hypertensive rats by Tanabe, Akiyo, Naruse, Mitsuhide, Hara, Yoshiko, Sato, Atsuhisa, Tsuchiya, Ken, Nishikawa, Toshio, Imaki, Toshihiro, Takano, Kazue

“…Background There is increasing evidence to support the importance of blocking aldosterone to prevent target-organ damage in hypertension. We recently…”
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Effect of Combination Therapy of Angiotensin-Converting Enzyme Inhibitor plus Calcium Channel Blocker on Urinary Albumin Excretion in Hypertensive Microalubuminuric Patients with Type II Diabetes by SHIGIHARA, Toshikatsu, SATO, Atsuhisa, HAYASHI, Koichi, SARUTA, Takao

“…It has been demonstrated that antihypertensive treatment of hypertensive diabetic patients is quite effective in preventing macrovascular and microvascular…”
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Plasma Aldosterone Concentrations Are Not Related to the Degree of Angiotensin-Converting Enzyme Inhibition in Essential Hypertensive Patients by SATO, Atsuhisa, SUZUKI, Yoshiyuki, SHIBATA, Hirotaka, SARUTA, Takao

“…There is increasing evidence of important cardiovascular effects of aldosterone via classical mineralocorticoid receptors in the heart. Aldosterone plus excess…”
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