Search Results - "SATHER, D. Noah"

Characteristics of the earliest cross-neutralizing antibody response to HIV-1 by Mikell, Iliyana, Sather, D Noah, Kalams, Spyros A, Altfeld, Marcus, Alter, Galit, Stamatatos, Leonidas

“…Recent cross-sectional analyses of HIV-1+ plasmas have indicated that broadly cross-reactive neutralizing antibody responses are developed by 10%-30% of HIV-1+…”
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Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus by Amanat, Fatima, Strohmeier, Shirin, Meade, Philip S, Dambrauskas, Nicholas, Mühlemann, Barbara, Smith, Derek J, Vigdorovich, Vladimir, Sather, D Noah, Coughlan, Lynda, Krammer, Florian

“…Vaccines against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) have been highly efficient in protecting against Coronavirus Disease 2019…”
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Malaria parasites target the hepatocyte receptor EphA2 for successful host infection by Kaushansky, Alexis, Douglass, Alyse N., Arang, Nadia, Vigdorovich, Vladimir, Dambrauskas, Nicholas, Kain, Heather S., Austin, Laura S., Sather, D. Noah, Kappe, Stefan H.I.

“…The invasion of a suitable host hepatocyte by mosquito-transmitted Plasmodium sporozoites is an essential early step in successful malaria parasite infection…”
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Germinal center activity and B cell maturation are associated with protective antibody responses against Plasmodium pre-erythrocytic infection by Visweswaran, Ganesh Ram R, Vijayan, Kamalakannan, Chandrasekaran, Ramyavardhanee, Trakhimets, Olesya, Brown, Samantha L, Vigdorovich, Vladimir, Yang, Ashton, Raappana, Andrew, Watson, Alex, Selman, William, Zuck, Meghan, Dambrauskas, Nicholas, Kaushansky, Alexis, Sather, D. Noah

“…Blocking Plasmodium , the causative agent of malaria, at the asymptomatic pre-erythrocytic stage would abrogate disease pathology and prevent transmission…”
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Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection by SATHER, D. Noah, ARMANN, Jakob, STAMATATOS, Leonidas, CHINE, Lance K, MAVRANTONI, Angeliki, SELLHORN, George, CALDWELL, Zachary, XUESONG YU, WOOD, Blake, SELF, Steve, KALAMS, Spyros

“…Author's Correction ( vol. 83 , p. 4713 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein by Klein, Florian, Gaebler, Christian, Mouquet, Hugo, Sather, D Noah, Lehmann, Clara, Scheid, Johannes F, Kraft, Zane, Liu, Yan, Pietzsch, John, Hurley, Arlene, Poignard, Pascal, Feizi, Ten, Morris, Lynn, Walker, Bruce D, Fätkenheuer, Gerd, Seaman, Michael S, Stamatatos, Leonidas, Nussenzweig, Michel C

“…Two to three years after infection, a fraction of HIV-1-infected individuals develop serologic activity that neutralizes most viral isolates. Broadly…”
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Oral Immunization with HIV-1 Envelope SOSIP trimers elicits systemic immune responses and cross-reactive anti-V1V2 antibodies in non-human primates by Fisher, Bridget S, Dambrauskas, Nicholas, Trakhimets, Olesya, Andrade, Daniela V, Smedley, Jeremy, Sodora, Donald L, Sather, D Noah

“…Development of a successful HIV vaccine is dependent upon a determination of the optimum antigen and adjuvant as well as choosing an optimal site for vaccine…”
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Platelet derived growth factor receptor β (PDGFRβ) is a host receptor for the human malaria parasite adhesin TRAP by Steel, Ryan W. J., Vigdorovich, Vladimir, Dambrauskas, Nicholas, Wilder, Brandon K., Arredondo, Silvia A., Goswami, Debashree, Kumar, Sudhir, Carbonetti, Sara, Swearingen, Kristian E., Nguyen, Thao, Betz, Will, Camargo, Nelly, Fisher, Bridget S., Soden, Jo, Thomas, Helen, Freeth, Jim, Moritz, Robert L., Noah Sather, D., Kappe, Stefan H. I.

“…Following their inoculation by the bite of an infected Anopheles mosquito, the malaria parasite sporozoite forms travel from the bite site in the skin into the…”
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Angiotensin II receptor I auto-antibodies following SARS-CoV-2 infection by Jiang, Yonghou, Duffy, Fergal, Hadlock, Jennifer, Raappana, Andrew, Styrchak, Sheila, Beck, Ingrid, Mast, Fred D, Miller, Leslie R, Chour, William, Houck, John, Armistead, Blair, Duvvuri, Venkata R, Yeung, Winnie, Haglund, Micaela, Wallner, Jackson, Wallick, Julie A, Hardy, Samantha, Oldroyd, Alyssa, Ko, Daisy, Gervassi, Ana, Murray, Kim M, Kaplan, Henry, Aitchison, John D, Heath, James R, Sather, D Noah, Goldman, Jason D, Frenkel, Lisa, Harrington, Whitney E

“…Coronavirus disease 2019 (COVID-19) is associated with endothelial activation and coagulopathy, which may be related to pre-existing or infection-induced…”
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Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage by Simonich, Cassandra A., Doepker, Laura, Ralph, Duncan, Williams, James A., Dhar, Amrit, Yaffe, Zak, Gentles, Lauren, Small, Christopher T., Oliver, Brian, Vigdorovich, Vladimir, Mangala Prasad, Vidya, Nduati, Ruth, Sather, D. Noah, Lee, Kelly K., Matsen IV, Frederick A., Overbaugh, Julie

“…HIV-infected infants develop broadly neutralizing plasma responses with more rapid kinetics than adults, suggesting the ontogeny of infant responses could…”
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Blood Stage Malaria Disrupts Humoral Immunity to the Pre-erythrocytic Stage Circumsporozoite Protein by Keitany, Gladys J., Kim, Karen S., Krishnamurty, Akshay T., Hondowicz, Brian D., Hahn, William O., Dambrauskas, Nicholas, Sather, D. Noah, Vaughan, Ashley M., Kappe, Stefan H.I., Pepper, Marion

“…Many current malaria vaccines target the pre-erythrocytic stage of infection in the liver. However, in malaria-endemic regions, increased blood stage exposure…”
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Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects by Kublin, James G, Mikolajczak, Sebastian A, Sack, Brandon K, Fishbaugher, Matt E, Seilie, Annette, Shelton, Lisa, VonGoedert, Tracie, Firat, Melike, Magee, Sara, Fritzen, Emma, Betz, Will, Kain, Heather S, Dankwa, Dorender A, Steel, Ryan W J, Vaughan, Ashley M, Noah Sather, D, Murphy, Sean C, Kappe, Stefan H I

“…Immunization of humans with whole sporozoites confers complete, sterilizing immunity against malaria infection. However, achieving consistent safety while…”
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Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs by Hoot, Sam, McGuire, Andrew T, Cohen, Kristen W, Strong, Roland K, Hangartner, Lars, Klein, Florian, Diskin, Ron, Scheid, Johannes F, Sather, D Noah, Burton, Dennis R, Stamatatos, Leonidas

“…Vaccine candidates for HIV-1 so far have not been able to elicit broadly neutralizing antibodies (bNAbs) although they express the epitopes recognized by bNAbs…”
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Plasma From Recovered COVID-19 Patients Inhibits Spike Protein Binding to ACE2 in a Microsphere-Based Inhibition Assay by Gniffke, Edward P, Harrington, Whitney E, Dambrauskas, Nicholas, Jiang, Yonghou, Trakhimets, Olesya, Vigdorovich, Vladimir, Frenkel, Lisa, Sather, D Noah, Smith, Stephen E P

“…Abstract We present a microsphere-based flow cytometry assay that quantifies the ability of plasma to inhibit the binding of spike protein to…”
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Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques by Wood, Matthew P, Jones, Chloe I, Lippy, Adriana, Oliver, Brian G, Walund, Brynn, Fancher, Katherine A, Fisher, Bridget S, Wright, Piper J, Fuller, James T, Murapa, Patience, Habib, Jakob, Mavigner, Maud, Chahroudi, Ann, Sather, D Noah, Fuller, Deborah H, Sodora, Donald L

“…HIV-infected infants are at an increased risk of progressing rapidly to AIDS in the first weeks of life. Here, we evaluated immunological and virological…”
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A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages by Schafer, Carola, Dambrauskas, Nicholas, Steel, Ryan W, Carbonetti, Sara, Chuenchob, Vorada, Flannery, Erika L, Vigdorovich, Vladimir, Oliver, Brian G, Roobsoong, Wanlapa, Maher, Steven P, Kyle, Dennis, Sattabongkot, Jetsumon, Kappe, Stefan H I, Mikolajczak, Sebastian A, Sather, D Noah

“…Plasmodium vivax is the most geographically widespread of the human malaria parasites, causing 50,000 to 100,000 deaths annually. Plasmodium vivax parasites…”
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Deep mutational scanning of the RNase III-like domain in Trypanosoma brucei RNA editing protein KREPB4 by McDermott, Suzanne M, Pham, Vy, Oliver, Brian, Carnes, Jason, Sather, D Noah, Stuart, Kenneth D

“…Kinetoplastid pathogens including , , and species, are early diverged, eukaryotic, unicellular parasites. Functional understanding of many proteins from these…”
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Differences in Allelic Frequency and CDRH3 Region Limit the Engagement of HIV Env Immunogens by Putative VRC01 Neutralizing Antibody Precursors by Yacoob, Christina, Pancera, Marie, Vigdorovich, Vladimir, Oliver, Brian G., Glenn, Jolene A., Feng, Junli, Sather, D. Noah, McGuire, Andrew T., Stamatatos, Leonidas

“…Elicitation of broadly neutralizing antibodies remains a long-standing goal of HIV vaccine research. Although such antibodies can arise during HIV-1 infection,…”
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Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody against antigenically distinct Omicron subvariants by Changrob, Siriruk, Halfmann, Peter J, Liu, Hejun, Torres, Jonathan L, McGrath, Joshua J C, Ozorowski, Gabriel, Li, Lei, Wilbanks, G Dewey, Kuroda, Makoto, Maemura, Tadashi, Huang, Min, Zheng, Nai-Ying, Turner, Hannah L, Erickson, Steven A, Fu, Yanbin, Yasuhara, Atsuhiro, Singh, Gagandeep, Monahan, Brian, Mauldin, Jacob, Srivastava, Komal, Simon, Viviana, Krammer, Florian, Sather, D Noah, Ward, Andrew B, Wilson, Ian A, Kawaoka, Yoshihiro, Wilson, Patrick C

“…The rapid evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variants has emphasized the need to identify antibodies with…”
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Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria by Watson, Felicia N., Shears, Melanie J., Kalata, Anya C., Duncombe, Caroline J., Seilie, A. Mariko, Chavtur, Chris, Conrad, Ethan, Cruz Talavera, Irene, Raappana, Andrew, Sather, D. Noah, Chakravarty, Sumana, Sim, B. Kim Lee, Hoffman, Stephen L., Tsuji, Moriya, Murphy, Sean C.

“…Radiation-attenuated sporozoite (RAS) vaccines can completely prevent blood stage Plasmodium infection by inducing liver-resident memory CD8 + T cells to…”
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