Search Results - "SASTRY, B. K. S"
-
1
Association between six-minute walk distance and long-term outcomes in patients with pulmonary arterial hypertension: Data from the randomized SERAPHIN trial
Published in PloS one (28-03-2018)“…Patients with pulmonary arterial hypertension who achieve a six-minute walk distance of 380-440 m may have improved prognosis. Using the randomized controlled…”
Get full text
Journal Article -
2
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of Oral Sildenafil Citrate in Treatment-Naive Children With Pulmonary Arterial Hypertension
Published in Circulation (New York, N.Y.) (17-01-2012)“…Safe, effective therapy is needed for pediatric pulmonary arterial hypertension. Children (n=235; weight ≥8 kg) were randomized to low-, medium-, or high-dose…”
Get full text
Journal Article -
3
Efficacy of 1, 5, and 20 mg oral sildenafil in the treatment of adults with pulmonary arterial hypertension: a randomized, double-blind study with open-label extension
Published in BMC pulmonary medicine (23-02-2017)“…In a previous study, 6-minute walk distance (6MWD) improvement with sildenafil was not dose dependent at the 3 doses tested (20, 40, and 80 mg 3 times daily…”
Get full text
Journal Article -
4
Infective endocarditis
Published in The Lancet (British edition) (27-07-2024)“…First described more than 350 years ago, infective endocarditis represents a global health concern characterised by infections affecting the native or…”
Get full text
Journal Article -
5
Monomorphic Ventricular Tachycardia and Mediastinal Adenopathy Due to Granulomatous Infiltration in Patients With Preserved Ventricular Function
Published in Journal of the American College of Cardiology (28-06-2011)“…Objectives This report characterizes a syndrome of granulomatous infiltration presenting as sustained monomorphic ventricular tachycardia (SMVT) with…”
Get full text
Journal Article -
6
Contribution of sudden cardiac death to total mortality in India — A population based study
Published in International journal of cardiology (26-01-2012)“…Abstract Introduction Epidemiology of sudden cardiac death (SCD) in India is understudied. Methods We assessed proportion of SCD among total mortality in a…”
Get full text
Journal Article -
7
Melatonin metabolite 6-Sulfatoxymelatonin, Cu/Zn superoxide dismutase, oxidized LDL and malondialdehyde in unstable angina
Published in International journal of cardiology (08-10-2010)“…Abstract Background Melatonin, a lypophylic antioxidant, was reported to be low in patients suffering from myocardial infarction, a disease due to coronary…”
Get full text
Journal Article -
8
Macitentan and Morbidity and Mortality in Pulmonary Arterial Hypertension
Published in The New England journal of medicine (29-08-2013)“…In an event-driven trial, macitentan (an endothelin-receptor antagonist) at a dose of 3 or 10 mg was compared with placebo in patients with symptomatic…”
Get full text
Journal Article -
9
Mitochondria‐targeted esculetin inhibits PAI‐1 levels by modulating STAT3 activation and miR‐19b via SIRT3: Role in acute coronary artery syndrome
Published in Journal of cellular physiology (01-01-2018)“…In this study we explored the microRNAs responsible for the regulation of PAI‐1 during LPS‐stimulated inflammation in human aortic endothelial cells and…”
Get full text
Journal Article -
10
Pulmonary Arterial Hypertension-Related Morbidity Is Prognostic for Mortality
Published in Journal of the American College of Cardiology (20-02-2018)“…Registry data suggest that disease progression in pulmonary arterial hypertension (PAH) is indicative of poor prognosis. However, the prognostic relevance of…”
Get full text
Journal Article -
11
SERAPHIN haemodynamic substudy: the effect of the dual endothelin receptor antagonist macitentan on haemodynamic parameters and NT-proBNP levels and their association with disease progression in patients with pulmonary arterial hypertension
Published in European heart journal (14-04-2017)“…The effect of macitentan on haemodynamic parameters and NT-proBNP levels was evaluated in pulmonary arterial hypertension (PAH) patients in the SERAPHIN study…”
Get full text
Journal Article -
12
Clinical efficacy of Sildenafil in Primary pulmonary hypertension: A randomized, placebo-controlled, double-blind, crossover study
Published in Journal of the American College of Cardiology (07-04-2004)“…In a randomized, double-blind, crossover design, we compared the efficacy of sildenafil with placebo in patients with primary pulmonary hypertension (PPH). The…”
Get full text
Journal Article -
13
Incident and prevalent cohorts with pulmonary arterial hypertension: insight from SERAPHIN
Published in The European respiratory journal (01-12-2015)“…In SERAPHIN, a long-term, randomised, controlled trial (NCT00660179) in pulmonary arterial hypertension (PAH), macitentan significantly reduced the risk of…”
Get full text
Journal Article -
14
Long-Term Safety, Tolerability and Survival in Patients with Pulmonary Arterial Hypertension Treated with Macitentan: Results from the SERAPHIN Open-Label Extension
Published in Advances in therapy (01-09-2022)“…Introduction In SERAPHIN, a long-term, event-driven, double-blind randomised controlled trial in pulmonary arterial hypertension (PAH), macitentan 10 mg…”
Get full text
Journal Article -
15
Ventricular Tachycardia and Tuberculous Lymphadenopathy: Sign of Myocardial Tuberculosis?
Published in Journal of the American College of Cardiology (20-01-2015)Get full text
Journal Article -
16
One-year clinical outcomes of different coronary drug eluting stents—Data from a prospective registry
Published in Indian heart journal (01-07-2018)“…We compared one-year clinical outcomes of different drug eluting stents (DES) used in a prospective observation registry maintained in two hospitals over three…”
Get full text
Journal Article -
17
Management algorithms for acute ST elevation myocardial infarction in less industrialized world
Published in Indian heart journal (01-04-2017)Get full text
Journal Article -
18
MAO-A promoter polymorphism and idiopathic pulmonary arterial hypertension
Published in Journal of genetics (01-12-2013)“…Monoamine oxidases (MAO) are mitochondrial enzymes that convert biogenic amines to their corresponding aldehydes. Two isoforms, MAO-A and MAO-B, exist which…”
Get full text
Journal Article -
19
Pharmacologic treatment for pulmonary arterial hypertension
Published in Current opinion in cardiology (01-11-2006)“…PURPOSE OF REVIEWPulmonary arterial hypertension (PAH) has been a disease with limited treatment options and poor prognosis. This article reviews the recent…”
Get full text
Journal Article -
20
Sudden cardiac death after acute ST elevation myocardial infarction: insight from a developing country
Published in Heart Asia (01-01-2012)“…BackgroundThere is no data concerning sudden cardiac death (SCD) following acute ST elevation myocardial infarction (STEMI) in India. We assessed the incidence…”
Get full text
Journal Article