Search Results - "SASAOKA, T"
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Calculation model of overburden subsidence in mined-out area based on Brillouin optical time-domain reflectometer technology
Published in International journal of rock mechanics and mining sciences (Oxford, England : 1997) (01-02-2021)“…With the increase of the coal consumption, the gob scale has become significantly large, increasing the risk of subsidence. Using Brillouin optical time-domain…”
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Role of orexin in the regulation of glucose homeostasis
Published in Acta Physiologica (01-03-2010)“…Orexin-A (hypocretin-1) and orexin-B (hypocretin-2) are hypothalamic neuropeptides that play key roles in the regulation of wakefulness, feeding, reward,…”
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Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons
Published in Molecular psychiatry (01-08-2017)“…Aberrant dopamine D 2 receptor (D 2 R) activity is associated with neuropsychiatric disorders, making those receptors targets for antipsychotic drugs. Here, we…”
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GABAergic synaptic transmission onto striatal cholinergic interneurons in dopamine D2 receptor knock-out mice
Published in Neuroscience (28-03-2014)“…Highlights • We used dopamine D2 receptor knock-out mice. • We examined frequency-dependent suppression of striatal inhibitory transmission. • Physiologically…”
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Endocytosis following dopamine D 2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons
Published in Molecular psychiatry (01-08-2017)“…Aberrant dopamine D receptor (D R) activity is associated with neuropsychiatric disorders, making those receptors targets for antipsychotic drugs. Here, we…”
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Journal Article -
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Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice
Published in Diabetologia (01-04-2008)“…Aims/hypothesis Orexin/hypocretin is a hypothalamic neuropeptide that regulates motivated behaviours, such as feeding and arousal, and, importantly, is also…”
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Evaluating the Influence of Underground Mining Sequence under an Open Pit Mine
Published in Journal of mining science (2022)“…For this study, as part of the underground operations, the underground mining sequence was explored for suitability in the Zuuntsagaan mine. Two mining…”
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Review on the in vitro interaction of insulin glargine with the insulin/insulin-like growth factor system: potential implications for metabolic and mitogenic activities
Published in Hormone and metabolic research (01-01-2011)“…Insulin analogues provide clinically important benefits for people with diabetes, including more predictable action profiles and lower risk of hypoglycemia…”
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SH2-Containing Inositol 5′-Phosphatase 2 Selectively Impairs Hypothalamic Insulin Signalling and Regulation of Food Intake in Mice
Published in Journal of neuroendocrinology (01-04-2013)“…SH2‐containing inositol 5′‐phosphatase 2 (SHIP2) is a lipid phosphatase that negatively regulates the metabolic signalling of insulin in peripheral tissues;…”
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G.P.88
Published in Neuromuscular disorders : NMD (01-10-2014)“…Duchenne muscular dystrophy (DMD) is a fatal genetic disease. The fibers of muscle in DMD patients easily suffer necrotic change, because of the loss of…”
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Dopamine D2 Long Receptor-Deficient Mice Display Alterations in Striatum-Dependent Functions
Published in The Journal of neuroscience (15-11-2000)“…The dopamine D2 receptor (D2) system has been implicated in several neurological and psychiatric disorders, such as schizophrenia and Parkinson's disease…”
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Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy
Published in Nature genetics (01-08-1997)“…Hypertrophic cardiomyopathy (HCM), the most common cause of sudden death in the young, is an autosomal dominant disease characterized by ventricular…”
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Overexpression of SH2-Containing Inositol Phosphatase 2 Results in Negative Regulation of Insulin-Induced Metabolic Actions in 3T3-L1 Adipocytes via Its 5′-Phosphatase Catalytic Activity
Published in Molecular and Cellular Biology (01-03-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction
Published in The Journal of biological chemistry (19-08-1994)“…Syp (SH-PTP2) was recently identified as a phosphotyrosine phosphatase containing two SH2 domains within its primary structure. In response to appropriate…”
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Nelfinavir-induced insulin resistance is associated with impaired plasma membrane recruitment of the PI 3-kinase effectors Akt/PKB and PKC-ζ
Published in Diabetologia (01-06-2004)“…Chronic exposure of 3T3-L1 adipocytes to the HIV protease inhibitor nelfinavir induces insulin resistance, recapitulating key metabolic alterations of adipose…”
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Common Occurrence of Everolimus-Associated Aphthous Stomatitis in Japanese Heart Transplant Recipients
Published in Transplantation proceedings (01-11-2010)“…Abstract Mammalian target of rapamycin (mTOR) inhibitors display antiproliferative effects with less nephrotoxicity than calcineurin inhibitors. However,…”
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Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor
Published in The Journal of biological chemistry (06-05-1994)“…Shc proteins contain a single SH2 domain, lack catalytic activity, and are substrates for activated receptors for insulin, insulin-like growth factor-1…”
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368: Sympathetic Reinnervation Assessed by Iodine-123 Metaiodobenzylguanidine Imaging Are Not Consistent with the Response of Left Ventricular Function to Adrenergic Stimulation in Heart Transplant Recipients
Published in The Journal of heart and lung transplantation (01-02-2009)Get full text
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