Search Results - "SASAKI, KATSUNORI"
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Growth stimulation of Bifidobacterium from human colon using daikenchuto in an in vitro model of human intestinal microbiota
Published in Scientific reports (25-02-2021)“…Daikenchuto (DKT) is a Japanese traditional herbal (Kampo) medicine containing ginseng, processed ginger, and Japanese or Chinese pepper. We aimed to determine…”
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2
Prognostic relevance of tertiary lymphoid organs following neoadjuvant chemoradiotherapy in pancreatic ductal adenocarcinoma
Published in Cancer science (01-06-2019)“…The efficacy of preoperative neoadjuvant chemoradiotherapy (NAC) in cases of pancreatic cancer with extremely poor prognoses has been reported. In this study,…”
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3
Large-scale generation of differentiated cells to achieve regenerative medicine
Published in Stem cell research & therapy (20-01-2014)“…The effects of microgravity and fluid dynamic stress on embryoid bodies generated from pluripotent stem cells induce and direct their differentiation. Using…”
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4
Exhaustion, rather than lack of infiltration and persistence, of CAR-T cells hampers the efficacy of CAR-T therapy in an orthotopic PDAC xenograft model
Published in Biomedicine & pharmacotherapy (01-01-2024)“…Chimeric antigen receptor T-cell (CAR-T) therapy has demonstrated impressive success in the treatment of patients with hematologic tumors yet achieved very…”
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5
Quantitative profiling of glucosinolates by LC–MS analysis reveals several cultivars of cabbage and kale as promising sources of sulforaphane
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-08-2012)“…► We upgraded the LC–MS system with a reversed-phase C30 column for glucosinolates. ► This method is a suitable tool for profiling glucosinolates contained in…”
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6
Iron overload signature in chrysotile-induced malignant mesothelioma
Published in The Journal of pathology (01-11-2012)“…Exposure to asbestos is a risk for malignant mesothelioma (MM) in humans. Among the commercially used types of asbestos (chrysotile, crocidolite, and amosite),…”
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7
A simple three-dimensional gut model constructed in a restricted ductal microspace induces intestinal epithelial cell integrity and facilitates absorption assays
Published in Biomaterials science (21-10-2020)“…The intestine acts as a center for nutrient and water absorption at the epithelium and plays an important role in immunity. Considering the complexity of its…”
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8
Cell biological profiling of reprogrammed cancer stem cell-like colon cancer cells maintained in culture
Published in Cell and tissue research (01-03-2019)“…Cancer stem cells (CSCs) are specific targets for therapeutic applications, but the rarity of CSCs within tumors makes the isolation of CSCs difficult. To…”
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9
Role of Dimerized C16orf74 in Aggressive Pancreatic Cancer: A Novel Therapeutic Target
Published in Molecular cancer therapeutics (01-01-2020)“…Over the past 30 years, the therapeutic outcome for pancreatic ductal adenocarcinoma (PDAC) has remained stagnant due to the lack of effective treatments. We…”
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10
Enrichment of Pluripotent Stem Cell-Derived Hepatocyte-Like Cells by Ammonia Treatment
Published in PloS one (15-09-2016)“…Embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are potential resources for the regeneration of defective organs, including the liver…”
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11
Bone morphogenetic protein-4 promotes induction of cardiomyocytes from human embryonic stem cells in serum-based embryoid body development
Published in American journal of physiology. Heart and circulatory physiology (01-06-2009)“…Cardiomyocytes derived from human embryonic stem (ES) cells are a potential source for cell-based therapy for heart diseases. We studied the effect of bone…”
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12
BDNF Gene-Modified Mesenchymal Stem Cells Promote Functional Recovery and Reduce Infarct Size in the Rat Middle Cerebral Artery Occlusion Model
Published in Molecular therapy (01-02-2004)“…Examination of the clinical therapeutic efficacy of using bone marrow stromal cells, including mesenchymal stem cells (MSC), has recently been the focus of…”
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13
Earlobe-like peritoneal appendage near the angle of His: a useful landmark for demarcating the lateral margin of the gastric cardia
Published in Anatomical science international (01-01-2018)“…The gastric cardia—the small area around the cardiac orifice including the abdominal esophagus—is an important target area for abdominal and thoracic…”
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14
Simple estimate of filtration rates on a sandy beach
Published in Limnology (2018)“…A new, simple and inexpensive method is proposed to determine the rate of water filtration in the swash zone of lakeshore beaches. Rates of water filtration on…”
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15
Iron-induced epigenetic abnormalities of mouse bone marrow through aberrant activation of aconitase and isocitrate dehydrogenase
Published in International journal of hematology (01-10-2016)“…Iron overload remains a concern in myelodysplastic syndrome (MDS) patients. Iron chelation therapy (ICT) thus plays an integral role in the management of these…”
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16
Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells
Published in PloS one (21-01-2010)“…The hedgehog (Hh) pathway has been implicated in the pathogenesis of cancer including pancreatic ductal adenocarcinoma (PDAC). Recent studies have suggested…”
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17
FGF7 and cell density are required for final differentiation of pancreatic amylase-positive cells from human ES cells
Published in Cell and tissue research (01-12-2013)“…The major molecular signals of pancreatic exocrine development are largely unknown. We examine the role of fibroblast growth factor 7 (FGF7) in the final…”
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Patients' Induced Pluripotent Stem Cells to Model Drug Induced Adverse Events: A Role in Predicting Thiopurine Induced Pancreatitis?
Published in Current drug metabolism (01-01-2016)“…Induced pluripotent stem cells (iPSC) can be produced from adult cells by transfecting them with a definite set of pluripotency-associated genes. Under…”
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Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice
Published in International journal of pharmaceutics (10-11-1999)“…We have examined the size dependence of extravasation and interstitial localization of polyethyleneglycol-coated liposomes (PEG-liposomes) in the solid tumor…”
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20
A selective splicing variant of hepcidin mRNA in hepatocellular carcinoma cell lines
Published in Biochemical and biophysical research communications (05-08-2016)“…Hepcidin is a main regulator of iron metabolism, of which abnormal expression affects intestinal absorption and reticuloendothelial sequestration of iron by…”
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