Vitamin E Deficiency in a Child with Intestinal Lymphangiectasia

Vitamin E Deficiency in a Child with Intestinal Lymphangiectasia

In a seven-year-old boy with the protein-losing enteropathy due to an intestinal lymphangiectasia, a marked deficiency of both vitamin E and essential fatty acids of erythrocytes was found and urinary excretion of methylmalonic acid was detectable after an oral loading with valine. The amount of vit...

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Bibliographic Details
Published in:The Tohoku Journal of Experimental Medicine Vol. 102; no. 2; pp. 169 - 178
Main Authors: HIGASHI, OTOTAKA, FUJIWARA, TETSURO, ARAKAWA, TSUNEO, KONNO, TASUKE, ITO, EISUKE, HONDA, YOSHIYUKI, SANJO, MASAHIDE, SASAKI, FUMIHIDE, YOSHIMURA, YOZO, TSUCHIDA, SHUJI
Format: Journal Article
Language:English
Published: Japan Tohoku University Medical Press 01-01-1970
Subjects:
Biopsy
Child
Duodenum - pathology
Erythrocytes - analysis
Fatty Acids - blood
Hemolysis
Humans
Hydrogen Peroxide
Intestinal Diseases - complications
intestinal lymphangieetasia
Lymphangiectasis - complications
Lymphangiectasis - diagnosis
Lymphangiectasis - diagnostic imaging
Lymphangiectasis - pathology
Lymphography
Male
Malonates - urine
methylmalonic acid
Protein-Losing Enteropathies - etiology
Valine
Vitamin E - therapeutic use
Vitamin E deficiency
Vitamin E Deficiency - diagnosis
Vitamin E Deficiency - drug therapy
Vitamin E Deficiency - etiology
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Summary:In a seven-year-old boy with the protein-losing enteropathy due to an intestinal lymphangiectasia, a marked deficiency of both vitamin E and essential fatty acids of erythrocytes was found and urinary excretion of methylmalonic acid was detectable after an oral loading with valine. The amount of vitamin E, administered parenterally, required to maintain a normal hydrogen peroxide hemolysis test of erythrocytes was found to be about 7mg per day in the patient.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0040-8727
1349-3329
DOI:10.1620/tjem.102.169