Search Results - "SARTI, Manuela"

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer by Chen, Jingjing, Guccini, Ilaria, Di Mitri, Diletta, Brina, Daniela, Revandkar, Ajinkya, Sarti, Manuela, Pasquini, Emiliano, Alajati, Abdullah, Pinton, Sandra, Losa, Marco, Civenni, Gianluca, Catapano, Carlo V., Sgrignani, Jacopo, Cavalli, Andrea, D’Antuono, Rocco, Asara, John M., Morandi, Andrea, Chiarugi, Paola, Crotti, Sara, Agostini, Marco, Montopoli, Monica, Masgras, Ionica, Rasola, Andrea, Garcia-Escudero, Ramon, Delaleu, Nicolas, Rinaldi, Andrea, Bertoni, Francesco, Bono, Johann de, Carracedo, Arkaitz, Alimonti, Andrea

“…The mechanisms by which mitochondrial metabolism supports cancer anabolism remain unclear. Here, we found that genetic and pharmacological inactivation of…”
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Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity by Toso, Alberto, Revandkar, Ajinkya, Di Mitri, Diletta, Guccini, Ilaria, Proietti, Michele, Sarti, Manuela, Pinton, Sandra, Zhang, Jiangwen, Kalathur, Madhuri, Civenni, Gianluca, Jarrossay, David, Montani, Erica, Marini, Camilla, Garcia-Escudero, Ramon, Scanziani, Eugenio, Grassi, Fabio, Pandolfi, Pier Paolo, Catapano, Carlo V, Alimonti, Andrea

“…Prosenescence therapy has recently emerged as a novel therapeutic approach for treating cancer. However, this concept is challenged by conflicting evidence…”
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RNAi-Mediated Silencing of Myc Transcription Inhibits Stem-like Cell Maintenance and Tumorigenicity in Prostate Cancer by CIVENNI, Gianluca, MALEK, Anastasia, ALBINO, Domenico, GARCIA-ESCUDERO, Ramon, NAPOLI, Sara, DI MARCO, Stefano, PINTON, Sandra, SARTI, Manuela, CARBONE, Giuseppina M, CATAPANO, Carlo V

“…Several studies link disease progression, recurrence, and treatment failures to the cancer stem-like cell (CSC) subpopulation within the heterogeneous tumor…”
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Interaction of CDCP1 with HER2 enhances HER2-driven tumorigenesis and promotes trastuzumab resistance in breast cancer by Alajati, Abdullah, Guccini, Ilaria, Pinton, Sandra, Garcia-Escudero, Ramon, Bernasocchi, Tiziano, Sarti, Manuela, Montani, Erica, Rinaldi, Andrea, Montemurro, Filippo, Catapano, Carlo, Bertoni, Francesco, Alimonti, Andrea

“…Understanding the molecular pathways that contribute to the aggressive behavior of HER2-positive breast cancers may aid in the development of novel therapeutic…”
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Ultrasound screening for abdominal aortic aneurysms by Engelberger, Stephan, Rosso, Raffaele, Sarti, Manuela, Del Grande, Filippo, Canevascini, Reto, van den Berg, Jos C, Prouse, Giorgio, Giovannacci, Luca

“…This pilot study aimed to assess the feasibility, acceptance and costs of an ultrasound scan screening programme for abdominal aortic aneurysms (AAA) in the…”
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Alterations of the Tumor Suppressor Gene Parkin in Non-Small Cell Lung Cancer by PICCHIO, Maria Cristina, SANTOS MARTIN, Eric, FISHEL, Richard, CROCE, Carlo Maria, CESARI, Rossano, CALIN, George Adrian, YENDAMURI, Sai, KUROKI, Tamotsu, PENTIMALLI, Francesca, SARTI, Manuela, YODER, Kristine, KAISER, Larry R

“…Purpose: Parkin , a gene mutated in autosomal recessive juvenile Parkinsonism and mapped to the common fragile site FRA6E on human chromosome 6q25-q27, is…”
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Adenoviral Transduction of TESTIN Gene into Breast and Uterine Cancer Cell Lines Promotes Apoptosis and Tumor Reduction In vivo by SARTI, Manuela, SEVIGNANI, Cinzia, NEGRINI, Massimo, CROCE, Carlo M, CALIN, George A, AQEILAN, Rami, SHIMIZU, Masayoshi, PENTIMALLI, Francesca, PICCHIO, Maria Cristina, GODWIN, Andrew, ROSENBERG, Anne, DRUSCO, Alessandra

“…Purpose: The human TESTIN ( TES ) gene is a putative tumor suppressor gene in the fragile chromosomal region FRA7G at 7q31.1/2 that was reported to be altered…”
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Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models by Trapasso, Francesco, Sarti, Manuela, Cesari, Rossano, Yendamuri, Sai, Dumon, Kristoffel R, Aqeilan, Rami I, Pentimalli, Francesca, Infante, Luisa, Alder, Hansjuerg, Abe, Nobutsugu, Watanabe, Takashi, Viglietto, Giuseppe, Croce, Carlo M, Fusco, Alfredo

“…Pancreatic carcinoma is one of the most aggressive tumors, and, being refractory to conventional therapies, is an excellent target for new therapeutic…”
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Tumour-infiltrating Gr-1+ myeloid cells antagonize senescence in cancer by Di Mitri, Diletta, Toso, Alberto, Chen, Jing Jing, Sarti, Manuela, Pinton, Sandra, Jost, Tanja Rezzonico, D’Antuono, Rocco, Montani, Erica, Garcia-Escudero, Ramon, Guccini, Ilaria, Da Silva-Alvarez, Sabela, Collado, Manuel, Eisenberger, Mario, Zhang, Zhe, Catapano, Carlo, Grassi, Fabio, Alimonti, Andrea

“…Senescence in cancer can be antagonized by a subset of immune cells acting in a non-cell-autonomous manner. Targeting cancer-cell senescence Induction of…”
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ESE3/EHF Controls Epithelial Cell Differentiation and Its Loss Leads to Prostate Tumors with Mesenchymal and Stem-like Features by ALBINO, Domenico, LONGONI, Nicole, CHIORINO, Giovanna, CATAPANO, Carlo V, CARBONE, Giuseppina M, CURTI, Laura, MELLO-GRAND, Maurizia, PINTON, Sandra, CIVENNI, Gianluca, THALMANN, George, D'AMBROSIO, Gioacchino, SARTI, Manuela, SESSA, Fausto

“…Cancer stem cells (CSC) play a significant role in tumor progression, disease recurrence, and treatment failure. Here, we show that the endogenously expressed…”
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ETS Transcription Factor ESE1/ELF3 Orchestrates a Positive Feedback Loop That Constitutively Activates NF-κB and Drives Prostate Cancer Progression by LONGONI, Nicole, SARTI, Manuela, SESSA, Fausto, GARCIA-ESCUDERO, Ramon, THALMANN, George N, CHIORINO, Giovanna, CATAPANO, Carlo V, CARBONE, Giuseppina M, ALBINO, Domenico, CIVENNI, Gianluca, MALEK, Anastasia, ORTELLI, Erica, PINTON, Sandra, MELLO-GRAND, Maurizia, OSTANO, Paola, D'AMBROSIO, Gioacchino

“…Chromosomal translocations leading to deregulated expression of ETS transcription factors are frequent in prostate tumors. Here, we report a novel mechanism…”
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A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours by Kalathur, Madhuri, Toso, Alberto, Chen, Jingjing, Revandkar, Ajinkya, Danzer-Baltzer, Claudia, Guccini, Ilaria, Alajati, Abdullah, Sarti, Manuela, Pinton, Sandra, Brambilla, Lara, Di Mitri, Diletta, Carbone, Giuseppina, Garcia-Escudero, R, Padova, Alessandro, Magnoni, Letizia, Tarditi, Alessia, Maccari, Laura, Malusa, Federico, Kalathur, Ravi Kiran Reddy, A. Pinna, Lorenzo, Cozza, Giorgio, Ruzzene, Maria, Delaleu, Nicolas, Catapano, Carlo V., Frew, Ian J., Alimonti, Andrea

“…Enhancement of cellular senescence in tumours triggers a stable cell growth arrest and activation of an antitumour immune response that can be exploited for…”
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Publisher Correction: Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer by Chen, Jingjing, Guccini, Ilaria, Di Mitri, Diletta, Brina, Daniela, Revandkar, Ajinkya, Sarti, Manuela, Pasquini, Emiliano, Alajati, Abdullah, Pinton, Sandra, Losa, Marco, Civenni, Gianluca, Catapano, Carlo V., Sgrignani, Jacopo, Cavalli, Andrea, D’Antuono, Rocco, Asara, John M., Morandi, Andrea, Chiarugi, Paola, Crotti, Sara, Agostini, Marco, Montopoli, Monica, Masgras, Ionica, Rasola, Andrea, Garcia-Escudero, Ramon, Delaleu, Nicolas, Rinaldi, Andrea, Bertoni, Francesco, de Bono, Johann, Carracedo, Arkaitz, Alimonti, Andrea

“…In the HTML version of this article initially published, the name of author Diletta Di Mitri was miscoded in the XML such that Di was included as part of the…”
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Abstract 1451: MicroRNAs regulated by ESE3/EHF control important mediators of epithelial cell differentiation and stemness in prostate tumors by Dallavalle, Cecilia, Albino, Domenico, Civenni, Gianluca, Ostano, Paola, Genini, Davide, Garcia-Escudero, Ramon, Curti, Laura, Pinton, Sandra, Sarti, Manuela, Chiorino, Giovanna, Catapano, Carlo V., Carbone, Giuseppina M. R.

“…Abstract Deregulated expression of ETS transcription factors has emerged as an important event in prostate cancer pathogenesis. We found that loss of the ETS…”
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Abstract 953: Novel inhibitors of signal transducer and activator of transcription 3 (STAT3) show potent activity in cell cultures and tumor xenografts by Genini, Davide, Brambilla, Lara, Laurini, Erik, Civenni, Gianluca, Pinton, Sandra, Sarti, Manuela, Garcia-Escudero, Ramon, Perez, Laurent, Carbone, Giuseppina M., Pricl, Sabrina, Catapano, Carlo V.

“…Abstract The transcription factor (TF) STAT3 is an attractive target for development of anticancer drugs. STAT3 is over-expressed and activated in many human…”
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Assessing the impact of bibliographical support on the quality of medical care in patients admitted to an internal medicine service: a prospective clinical, open, randomised two-arm parallel study by Pastori, Matteo Mario, Sarti, Manuela, Pons, Marco, Barazzoni, Fabrizio

“…To assess and quantify the impact of the literature in diagnostic decisions and treatment of patients admitted to an internal medicine service using the…”
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Correlation of UHRF1 expression in primary prostate cancer patients with adverse prognosis by Roggero, Enrico, Sarti, Manuela, Pinton, Sandra, Thalmann, George, Catapano, Carlo, Bonapace, Ian Marc, Carbone, Giuseppina

“…Abstract only 4661 Background: Cancer of the prostate is a leading cause of cancer death in western countries. There is a great need to understand the clinical…”
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Abstract 3307: Transcriptional silencing of c-Myc by promoter-directed siRNA efficiently target prostate cancer stem cells by Civenni, Gianluca, Malek, Anastasia, Albino, Domenico, Sarti, Manuela, Pinton, Sandra, Di Marco, Stefano, Carbone, Giuseppina M., Catapano, Carlo V.

“…Abstract Prostate cancer is the most frequent epithelial cancer in elderly men in Western countries. Depending on the stage, prostate cancer treatment requires…”
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Tumour-infiltrating Gr-[1.sup.+] myeloid cells antagonize senescence in cancer by Di Mitri, Diletta, Toso, Alberto, Chen, Jing Jing, Sarti, Manuela, Pinton, Sandra, Jost, Tanja Rezzonico, D'Antuono, Rocco, Montani, Erica, Garcia-Escudero, Ramon, Guccini, Ilaria, Da Silva-Alvarez, Sabela, Collado, Manuel, Eisenberger, Mario, Zhang, Zhe, Catapano, Carlo, Grassi, Fabio, Alimonth, Andrea

“…Aberrant activation of oncogenes or loss of tumour suppressor genes opposes malignant transformation by triggering a stable arrest in cell growth, which is…”
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Tumour-infiltrating Gr-1^sup +^ myeloid cells antagonize senescence in cancer by Di Mitri, Diletta, Toso, Alberto, Chen, Jing Jing, Sarti, Manuela, Pinton, Sandra, Jost, Tanja Rezzonico, D'Antuono, Rocco, Montani, Erica, Garcia-Escudero, Ramon, Guccini, Ilaria, Da Silva-Alvarez, Sabela, Collado, Manuel, Eisenberger, Mario, Zhang, Zhe, Catapano, Carlo, Grassi, Fabio, Alimonti, Andrea

“…Aberrant activation of oncogenes or loss of tumour suppressor genes opposes malignant transformation by triggering a stable arrest in cell growth, which is…”
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