Search Results - "SARIPINAR, Emin"

Molecular docking and 4D-QSAR model of methanone derivatives by electron conformational-genetic algorithm method by Tüzün, Burak, Saripinar, Emin

“…In our QSAR study, pharmacophore identification and biological activity estimation of 80 methanone derivatives were performed with the Electron Conformation…”
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A novel hybrid method named electron conformational genetic algorithm as a 4D QSAR investigation to calculate the biological activity of the tetrahydrodibenzazosines by Sahin, Kader, Saripinar, Emin

“…To understand the structure–activity correlation of a group of tetrahydrodibenzazocines as inhibitors of 17β‐hydroxysteroid dehydrogenase type 3, we have…”
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A Convenient Synthesis of Functionalized 1H-Pyrimidine-2-ones/thiones, Pyridazine and Imidazole; Experimental Data and PM3 Calculations by Sarıpınar, Emin, Yilmaz, Çigdem, Ünal, Dilek, Özer Ilhan, Ilhan, Yazır, Nihal, Akçamur, Yunus

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Pharmacophore Modelling and 4D-QSAR Study of Ruthenium(II) Arene Complexes as Anticancer Agents (Inhibitors) by Electron Conformational- Genetic Algorithm Method by Yavuz, Sevtap Caglar, Sabanci, Nazmiye, Saripinar, Emin

“…The EC-GA method was employed in this study as a 4D-QSAR method, for the identification of the pharmacophore (Pha) of ruthenium(II) arene complex derivatives…”
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4D-QSAR Study of Some Pyrazole Pyridine Carboxylic Acid Derivatives By Electron Conformational-Genetic Algorithm Method by Tuzun, Burak, Yavuz, Sevtap Caglar, Sabanci, Nazmiye, Saripinar, Emin

“…In the present work, pharmacophore identification and biological activity prediction for 86 pyrazole pyridine carboxylic acid derivatives were made using the…”
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Efficient synthesis and molecular docking studies of new pyrimidine-chromeno hybrid derivatives as potential antiproliferative agents by Yavuz, Sevtap Çağlar, Akkoç, Senem, Tüzün, Burak, Şahin, Onur, Saripinar, Emin

“…Various novel heterocyclic compounds containing pyrimidine nuclei 5H-chromeno[4,3-d]pyrimidine (4a-c, e-h, l-r, t) and…”
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4D-QSAR analysis and pharmacophore modeling for alkynylphenoxyacetic acids as CRTh2 (DP2) receptor antagonists by KÖPRÜ, Semiha, SARIPINAR, Emin

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Synthesis, Characterization, Biological Activity and Molecular Modeling Studies of Novel Aminoguanidine Derivatives by Doğan, Nuriye, Yavuz, Sevtap Çağlar, Sahin, Kader, Orhan, Muge Didem, Muhammed, Hüseyin Kekec, Calis, Seyma, Küp, Fatma Öztürk, Avsar, Timucin, Akkoc, Senem, Tapera, Michael, Sahin, Onur, Kilic, Turker, Durdagi, Serdar, Saripinar, Emin

“…In recent years, various compounds including the aminoguanidine scaffold have been reported to exhibit diverse biological activities. In the current study, 16…”
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Crystal and Molecular Structure of 3,5-Diphenyl-4,5-dihydro-2-phenylcarboxamide-1H-pyrazole by Tanak, Hasan, İlhan, İlhan Özer, Dege, Necmi, Akın, Nazenin, Sarıpınar, Emin

“…Crystal structure of the title compound C 22 H 19 N 3 O is determined by single crystal X-ray diffraction (sp. gr. P 2 1 / c , Z = 4). The molecule as a whole,…”
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Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular docking studies of new imidazolyl hydrazone derivatives by Tapera, Michael, Kekeçmuhammed, Hüseyin, Tüzün, Burak, Sarıpınar, Emin, Koçyiğit, Ümit M., Yıldırım, Ebrar, Doğan, Murat, Zorlu, Yunus

“…•New series of hydrazones possessing imidazole hybrids.•Inhibitory activities of all derivatives were evaluated hCA I and hCA II.•Antiproliferative activities…”
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Synthesis and thermolysis of the 2,3‐dihydro‐1 H ‐pyrole‐2,3‐diones, pseudopericyclic reactions of formyl( N ‐phenylimidoyl)ketene: Experimental data and PM3 calculations by Saripinar, Emin, Karataş, Süleyman

“…The reactions of the 2,3‐dihydro‐1 H ‐furan‐2,3‐dione 1 with Schiff bases 2a‐f at 60–70°C furnish the corresponding 2,3‐dihydro‐1 H ‐pyrole‐2,3‐diones 3a‐f …”
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Molecular hybrids integrated with imidazole and hydrazone structural motifs: Design, synthesis, biological evaluation, and molecular docking studies by Tapera, Michael, Kekeçmuhammed, Hüseyin, Sarıpınar, Emin, Doğan, Murat, Tüzün, Burak, Koçyiğit, Ümit M., Çetin, Feyza Nur

“…•Synthesis of a new imidazole derivatives with a hydrazone moiety.•Evaluation of synthesized compounds for in vitro anticancer potential.•Inhibitory activities…”
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The cytotoxic activities of imidazole derivatives prepared from various guanylhydrazone and phenylglyoxal monohydrate by Yavuz, Sevtap Çağlar, Akkoç, Senem, Sarıpınar, Emin

“…A series of imidazole derivatives were synthesized from two-component condensation reaction of phenylgloxal monohydrate with guanylhydrazone. They were…”
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Synthesis, characterization, anti-tuberculosis activity and molecular modeling studies of thiourea derivatives bearing aminoguanidine moiety by Tapera, Michael, Kekeçmuhammed, Hüseyin, Sahin, Kader, Krishna, Vagolu Siva, Lherbet, Christian, Homberset, Håvard, Chebaiki, Mélina, Tønjum, Tone, Mourey, Lionel, Zorlu, Yunus, Durdagi, Serdar, Sarıpınar, Emin

“…•Synthesis of thiourea derivatives as antitubercular agents.•Evaluation of antimycobacterial activity by MABA.•Effective antitubercular agents with low…”
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Discovery of hydrazone containing thiadiazoles as Mycobacterium tuberculosis growth and enoyl acyl carrier protein reductase (InhA) inhibitors by Doğan, Hilal, Doğan, Şengül Dilem, Gündüz, Miyase Gözde, Krishna, Vagolu Siva, Lherbet, Christian, Sriram, Dharmarajan, Şahin, Onur, Sarıpınar, Emin

“…Tuberculosis, caused by Mycobacterium tuberculosis, is a serious infectious disease and remains a global health problem. There is an increasing need for the…”
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Experimental and theoretical studies on 3-(4-chlorophenyl)-5-(4-ethoxyphenyl)-4,5-dihydropyrazole-1-carbonitrile: DFT quantum mechanical calculation, vibrational band analysis, prediction of activity spectra, and molecular docking by Zeyrek, Celal Tuğrul, Akman, Soner, Ilhan, Ilhan Ozer, Kökbudak, Zülbiye, Sarıpınar, Emin, Akkoc, Senem

“…•A new compound was synthesized and fully characterized.•Theoretical calculations of compound were done.•PASS analysis of compound was implemented Synthesis,…”
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Antiproliferative activity and molecular docking studies of new 4-oxothiazolidin-5-ylidene acetate derivatives containing guanylhydrazone moiety by Al-Janabi, Ihab Adnan Salman, Yavuz, Sevtap Çağlar, Köprü, Semiha, Tapera, Michael, Kekeçmuhammed, Hüseyin, Akkoç, Senem, Tüzün, Burak, Patat, Şaban, Sarıpınar, Emin

“…•A series of 4-oxothiazolidin-5-ylidene acetate derivatives containing guaylhydrazone moiety was synthesized.•All the new synthesized compounds were…”
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Novel 1,2,4-triazole-maleamic acid derivatives: synthesis and evaluation as anticancer agents with carbonic anhydrase inhibitory activity by Tapera, Michael, Kekeçmuhammed, Hüseyin, Tüzün, Burak, Daştan, Sevgi Durna, Safa Çelik, Muhammed, Taslimi, Parham, Dastan, Taner, Topcu, Kubra Sena Bas, Cacan, Ercan, Şahin, Onur, Sarıpınar, Emin

“…•Synthesis and characterization of a novel 1,2,4-triazole-maleamic acid.•Biological evaluation as anticancer agents and carbonic anhydrase…”
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Imidazole-based hydrazones as potent anti-colon cancer agents: Design, synthesis, biological evaluation and computational studies by Tapera, Michael, Doğan, Eylül, Şahin, Kader, Gözkamane, Gaye Alara, Kekeçmuhammed, Hüseyin, Sandal, Semiha, Gurkan, Ajda Coker, Bora, Rıfat Emin, Anber, Anber, Durdagi, Serdar, Zorlu, Yunus, Sarıpınar, Emin

“…•Synthesis of imidazole and hydrazone hybrids as anticancer agents.•The inhibitive effect of synthesized compounds on HCT-116 and HT-29 cell…”
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Synthesis, Molecular Docking and Antiproliferative Activity Studies of a Thiazole‐Based Compound Linked to Hydrazone Moiety by Kekeçmuhammed, Hüseyin, Tapera, Michael, Tüzün, Burak, Akkoç, Senem, Zorlu, Yunus, Sarıpınar, Emin

“…(A new 4‐oxothiazolidin‐2‐ylidene derivative bearing hydrazone moiety was synthesized via Michael addition between the reaction of…”
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