Search Results - "SARESELLA, Marina"
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The Role of the Inflammasome in Neurodegenerative Diseases
Published in Molecules (Basel, Switzerland) (11-02-2021)“…Neurodegenerative diseases are chronic, progressive disorders that occur in the central nervous system (CNS). They are characterized by the loss of neuronal…”
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The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer's disease
Published in Molecular neurodegeneration (03-03-2016)“…Interleukin-1 beta (IL-1β) and its key regulator, the inflammasome, are suspected to play a role in the neuroinflammation observed in Alzheimer's disease (AD);…”
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Alterations in Circulating Fatty Acid Are Associated With Gut Microbiota Dysbiosis and Inflammation in Multiple Sclerosis
Published in Frontiers in immunology (07-07-2020)“…Butyric acid (BA) is a short-chain fatty acid (SCFA) with anti-inflammatory properties, which promotes intestinal barrier function. Medium-chain fatty acids…”
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Immunological and Clinical Effect of Diet Modulation of the Gut Microbiome in Multiple Sclerosis Patients: A Pilot Study
Published in Frontiers in immunology (25-10-2017)“…Pathogenesis of autoimmune disorders, including multiple sclerosis (MS), has been linked to an alteration of the resident microbial commensal community and of…”
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IL-33 and its decoy sST2 in patients with Alzheimer's disease and mild cognitive impairment
Published in Journal of neuroinflammation (06-06-2020)“…Interleukin-33 is a cytokine endowed with pro- and anti-inflammatory properties that plays a still poorly defined role in the pathogenesis of a number of…”
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Inflammatory Cytokines During Cardiac Rehabilitation After Heart Surgery and Their Association to Postoperative Atrial Fibrillation
Published in Scientific reports (25-05-2020)“…Inflammation is associated with atrial fibrillation (AF), but little is known about the association of AF with the inflammatory serum cytokines after the acute…”
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A straightforward LC-MS/MS analysis to study serum profile of short and medium chain fatty acids
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-10-2020)“…•LC-MS/MS method for the detection of SMCFAs in human serum.•Effortless derivatization step with 3-NPH.•Determination of the physiological range of SMCFAs in…”
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Salivary cortisol concentration after high-intensity interval exercise: Time of day and chronotype effect
Published in Chronobiology international (03-07-2017)“…Due to personal and working necessities, the time for exercise is often short, and scheduled early in the morning or late in the afternoon. Cortisol plays a…”
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Innate immune responses to three doses of the BNT162b2 mRNA SARS-CoV-2 vaccine
Published in Frontiers in immunology (22-08-2022)“…To explore the effects of SARS-CoV-2-mRNA vaccines on innate immune responses we enrolled 58 individuals who received 3 doses of the BNT162b2 vaccine in a…”
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10
TREM2 Expression and Amyloid-Beta Phagocytosis in Alzheimer's Disease
Published in International journal of molecular sciences (11-05-2023)“…Alzheimer's Disease is the most common form of dementia; its key pathological findings include the deposition of extracellular-neurotoxic-plaques composed of…”
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Inflammatory Responses to Monomeric and Aggregated α-Synuclein in Peripheral Blood of Parkinson Disease Patients
Published in Frontiers in neuroscience (25-03-2021)“…To investigate whether different forms of α-synuclein (α-syn) proteins can induce inflammation and activate the NLRP3 inflammasome, we stimulated with…”
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Investigating the effects of a daily multidisciplinary intensive outpatient rehabilitation program on innovative biomarkers in people with Parkinson's disease: Study protocol for a phase III randomized controlled clinical trial
Published in PloS one (23-10-2024)“…To date, there has been no medication that has prevented the progression of Parkinson's disease (PD). Many benefits of intensive and multidisciplinary…”
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Influence of a High-Impact Multidimensional Rehabilitation Program on the Gut Microbiota of Patients with Multiple Sclerosis
Published in International journal of molecular sciences (01-07-2021)“…Multiple sclerosis (MS) is a neurodegenerative inflammatory condition mediated by autoreactive immune processes. Due to its potential to influence host…”
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NK Cell Subpopulations and Receptor Expression in Recovering SARS-CoV-2 Infection
Published in Molecular neurobiology (01-12-2021)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the pandemic of coronavirus disease (COVID-19). Whereas in most cases…”
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Deregulation of IL-37 and its miRNAs modulators in sarcopenic patients after rehabilitation
Published in Journal of translational medicine (26-04-2021)“…sarcopenia is a highly prevalent condition in elderly individuals which is characterized by loss of muscle mass and functions; recent results showed that it is…”
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Leishmania infantum infection reduces the amyloid β42-stimulated NLRP3 inflammasome activation
Published in Brain, behavior, and immunity (01-08-2020)“…•L. infantum infection reduces nigericin or Aβ42-stimulated NLRP3 inflammasome activation.•L. infantum infection induces an anti-inflammatory milieu in…”
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Herpes simplex virus-1 (HSV-1) infection induces a potent but ineffective IFN-λ production in immune cells of AD and PD patients
Published in Journal of translational medicine (27-08-2019)“…The sequential activation of immediate early (IE), early (E) and late (L) genes is required to allow productive herpes simplex virus type 1 (HSV-1) infection…”
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The non-pathogenic protozoon Leishmania tarentolae interferes with the activation of NLRP3 inflammasome in human cells: new perspectives in the control of inflammation
Published in Frontiers in immunology (2024)“…Innate immune responses against infectious agents can act as triggers of inflammatory diseases. On the other hand, various pathogens have developed mechanisms…”
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A role for the TIM‐3/GAL‐9/BAT3 pathway in determining the clinical phenotype of multiple sclerosis
Published in The FASEB journal (01-11-2014)“…T‐cell immunoglobulin and mucin domain 3 (Tim‐3) ligates galectin‐9 (Gal‐9); this process, resulting in the inhibition of Th1 responses and in the apoptosis of…”
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Alterations of natural killer cells activatory molecules phenotype and function in mothers of ASD children: a pilot study
Published in Frontiers in immunology (20-07-2023)“…Autism spectrum disorder (ASD) is accompanied by complex immune alterations and inflammation, and the possible role played by Natural Killer (NK) in such…”
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