Search Results - "SARCHIELLI, E"
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Testosterone positively regulates vagina NO-induced relaxation: an experimental study in rats
Published in Journal of endocrinological investigation (01-06-2022)“…Purpose Female sexual response involves a complex interplay between neurophysiological mechanisms and the nitric oxide (NO)-mediated relaxation of clitoris and…”
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Treatment potential of LPCN 1144 on liver health and metabolic regulation in a non-genomic, high fat diet induced NASH rabbit model
Published in Journal of endocrinological investigation (01-10-2021)“…Purpose Low free testosterone (T) level in men is independently associated with presence and severity of Non-Alcoholic Steatohepatitis (NASH). The histological…”
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Therapeutic effects of obeticholic acid (OCA) treatment in a bleomycin-induced pulmonary fibrosis rat model
Published in Journal of endocrinological investigation (01-03-2019)“…Purpose We recently demonstrated a protective effect of the farnesoid X receptor agonist obeticholic acid (OCA) in rat models of bleomycin-induced pulmonary…”
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A unique neuroendocrine cell model derived from the human foetal neural crest
Published in Journal of endocrinological investigation (01-09-2020)“…Purpose Nowadays, no human neuroendocrine cell models derived from the neural crest are available. In this study, we present non-transformed long-term primary…”
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Therapeutic effects of the selective farnesoid X receptor agonist obeticholic acid in a monocrotaline-induced pulmonary hypertension rat model
Published in Journal of endocrinological investigation (01-08-2019)“…Background Activation of the farnesoid X receptor (FXR), a member of the nuclear receptor steroid superfamily, leads to anti-inflammatory and anti-fibrotic…”
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The phosphodiesterase 5 inhibitor tadalafil regulates lipidic homeostasis in human skeletal muscle cell metabolism
Published in Endocrine (01-03-2018)“…Purpose Tadalafil seems to ameliorate insulin resistance and glucose homeostasis in humans. We have previously reported that tadalafil targets human skeletal…”
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Opposite effects of tamoxifen on metabolic syndrome-induced bladder and prostate alterations: A role for GPR30/GPER?
Published in The Prostate (01-01-2014)“…BACKGROUND BPH and LUTS have been associated to obesity, hypogonadism, and metabolic syndrome (MetS). MetS‐induced prostate and bladder alterations, including…”
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Fibroblast growth factor and endothelin-1 receptors mediate the response of human striatal precursor cells to hypoxia
Published in Neuroscience (19-03-2015)“…Highlights • Hypoxia increases HSP cell proliferation at 48 h and reduces cell survival at 72 h. • HSP cells express FGF2 and ET-1 suggesting endogenous…”
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Elocalcitol Inhibits Inflammatory Responses in Human Thyroid Cells and T Cells
Published in Endocrinology (Philadelphia) (01-07-2008)“…T-helper 1 (Th1) cell-mediated inflammatory responses predominate in the early pathogenesis of Graves’ disease (GD), whereas Th2 cell-mediated immunity may…”
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Methimazole inhibits CXC chemokine ligand 10 secretion in human thyrocytes
Published in Journal of endocrinology (01-10-2007)“…CXC chemokine ligand 10 (CXCL10) plays a pivotal role in the self-perpetuation of the inflammatory processes in patients with autoimmune thyroid disease…”
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Immunomodulatory effects of BXL-01-0029, a less hypercalcemic vitamin D analogue, in human cardiomyocytes and T cells
Published in Experimental cell research (15-01-2009)“…Current immunosuppressive protocols have reduced rejection occurrence in heart transplantation; nevertheless, management of heart transplant recipients is…”
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Can baseball improve balance in blind subjects?
Published in Journal of sports medicine and physical fitness (01-06-2011)“…Baseball, one of the most popular sports in the world, is a fast-moving sport that requires various motor abilities. Baseball is played also by blind subjects…”
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(082) The Effect of Sex Steroids on RhoA/ROCK Pathway in Rat Distal Vagina
Published in Journal of sexual medicine (22-05-2023)“…Abstract Introduction The RhoA/ROCK calcium-sensitizing pathway plays a role in clitoral contractility, and therefore we deemed interesting to investigate its…”
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Distal Vagina Smooth Muscle Contractility Mechanisms: Effects of in Vivo Sex Steroids Treatment in an Animal Experimental Model of Ovariectomy
Published in Journal of sexual medicine (01-08-2022)“…Female sexual response is a complex phenomenon that involves multiple psychophysiological factors. Sex steroids play a fundamental role in the mechanisms of…”
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037 Immunomodulatory Effects of Dihydrotestosterone (DHT) in Rat Vaginal Smooth Muscle Cells
Published in Journal of sexual medicine (01-06-2019)Get full text
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PS-04-010 Effects of physical exercise on metabolic syndrome-associated hypogonadotropic hypogonadism and erectile dysfunction
Published in Journal of sexual medicine (01-05-2019)Get full text
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PS-04-006 Immunomodulatory effects of Dihydrotestosterone (DHT) in rat vaginal smooth muscle cells
Published in Journal of sexual medicine (01-05-2019)Get full text
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