Search Results - "SAPONE, Anna"
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Celiac disease: a comprehensive current review
Published in BMC medicine (23-07-2019)“…Celiac disease remains a challenging condition because of a steady increase in knowledge tackling its pathophysiology, diagnosis, management, and possible…”
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Spectrum of gluten-related disorders: consensus on new nomenclature and classification
Published in BMC medicine (07-02-2012)“…A decade ago celiac disease was considered extremely rare outside Europe and, therefore, was almost completely ignored by health care professionals. In only 10…”
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3
Blood-brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders
Published in Molecular autism (29-11-2016)“…Autism spectrum disorders (ASD) are complex conditions whose pathogenesis may be attributed to gene-environment interactions. There are no definitive…”
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Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity
Published in BMC medicine (09-03-2011)“…Celiac disease (CD) is an autoimmune enteropathy triggered by the ingestion of gluten. Gluten-sensitive individuals (GS) cannot tolerate gluten and may develop…”
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Akkermansia muciniphila exerts immunomodulatory and anti-inflammatory effects on gliadin-stimulated THP-1 derived macrophages
Published in Scientific reports (24-02-2023)“…Macrophages (MQs) pro-inflammatory phenotype is triggered by gliadin peptides. Akkermansia muciniphila ( A. muciniphila ) showed to enhance the…”
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The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update
Published in Nutrients (21-11-2017)“…Gluten-related disorders have recently been reclassified with an emerging scientific literature supporting the concept of non-celiac gluten sensitivity (NCGS)…”
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Non-Celiac Gluten sensitivity: the new frontier of gluten related disorders
Published in Nutrients (26-09-2013)“…Non Celiac Gluten sensitivity (NCGS) was originally described in the 1980s and recently a "re-discovered" disorder characterized by intestinal and…”
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Journal Article Book Review -
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Diploid Wheats: Are They Less Immunogenic for Non-Celiac Wheat Sensitive Consumers?
Published in Cells (Basel, Switzerland) (03-08-2022)“…Non-celiac wheat sensitivity (NCWS) is a clinical entity induced by the ingestion of gluten that leads to intestinal and/or extraintestinal symptoms, and is…”
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Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines
Published in Scandinavian journal of gastroenterology (01-01-2006)“…Objective. Little is known about the interaction of gliadin with intestinal epithelial cells and the mechanism(s) through which gliadin crosses the intestinal…”
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Zonulin Upregulation Is Associated With Increased Gut Permeability in Subjects With Type 1 Diabetes and Their Relatives
Published in Diabetes (New York, N.Y.) (01-05-2006)“…Zonulin Upregulation Is Associated With Increased Gut Permeability in Subjects With Type 1 Diabetes and Their Relatives Anna Sapone 1 2 , Laura de Magistris 2…”
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Celiac Disease Histopathology Recapitulates Hedgehog Downregulation, Consistent with Wound Healing Processes Activation
Published in PloS one (09-12-2015)“…In celiac disease (CD), intestinal epithelium damage occurs secondary to an immune insult and is characterized by blunting of the villi and crypt hyperplasia…”
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Role of the Intestinal Tight Junction Modulator Zonulin in the Pathogenesis of Type I Diabetes in BB Diabetic-Prone Rats
Published in Proceedings of the National Academy of Sciences - PNAS (22-02-2005)“…Increased intestinal permeability has been observed in numerous human autoimmune diseases, including type-1 diabetes (T1D) and its' animal model, the BB-wor…”
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Potential tolerability of ancient grains in non-celiac wheat sensitivity patients: A preliminary evaluation
Published in Frontiers in medicine (28-09-2022)“…Background and aims A wheat-free diet (WFD) represents the elective treatment for Non-celiac Wheat Sensitivity (NCWS) patients. Preliminary reports have shown…”
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Nonceliac Gluten Sensitivity
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2015)“…During the past decade there has been an impressive increase in popularity of the gluten-free diet (GFD)—now the most trendy alimentary habit in the United…”
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Tight Junctions, Intestinal Permeability, and Autoimmunity
Published in Annals of the New York Academy of Sciences (01-05-2009)“…Autoimmune diseases are characterized by tissue damage and loss of function due to an immune response that is directed against specific organs. This review is…”
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Celiac Disease and Nonceliac Gluten Sensitivity: A Review
Published in JAMA : the journal of the American Medical Association (15-08-2017)“…IMPORTANCE: The prevalence of gluten-related disorders is rising, and increasing numbers of individuals are empirically trying a gluten-free diet for a variety…”
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Human gut derived-organoids provide model to study gluten response and effects of microbiota-derived molecules in celiac disease
Published in Scientific reports (07-05-2019)“…Celiac disease (CD) is an immune-mediated disorder triggered by gluten exposure. The contribution of the adaptive immune response to CD pathogenesis has been…”
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Alterations of the Intestinal Barrier in Patients With Autism Spectrum Disorders and in Their First‐degree Relatives
Published in Journal of pediatric gastroenterology and nutrition (01-10-2010)“…ABSTRACT Objectives: Intestinal permeability (IPT) was investigated in patients with autism as well as in their first‐degree relatives to investigate leaky gut…”
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Intestinal Dysbiosis and Yeast Isolation in Stool of Subjects with Autism Spectrum Disorders
Published in Mycopathologia (1975) (01-04-2017)“…High frequency of gastrointestinal yeast presence in ASD subjects was shown through a simple cultural approach ( Candida spp . in 57.5 % of ASDs and no…”
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Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms
Published in Annals of the New York Academy of Sciences (01-05-2009)“…Autoimmune diseases are characterized by tissue damage and loss of function due to an immune response that is directed against specific organs. This review is…”
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