Search Results - "SAPIENZA, Carmen"

Diet, Nutrition, and Cancer Epigenetics by Sapienza, Carmen, Issa, Jean-Pierre

“…The search for a connection between diet and human cancer has a long history in cancer research, as has interest in the mechanisms by which dietary factors…”
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Epigenetic changes and assisted reproductive technologies by Mani, Sneha, Ghosh, Jayashri, Coutifaris, Christos, Sapienza, Carmen, Mainigi, Monica

“…Children conceived by Assisted Reproductive Technologies (ART) are at moderately increased risk for a number of undesirable outcomes, including low birth…”
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DNA methylation and gene expression differences in children conceived in vitro or in vivo by Katari, Sunita, Turan, Nahid, Bibikova, Marina, Erinle, Oluwatoyin, Chalian, Raffi, Foster, Michael, Gaughan, John P., Coutifaris, Christos, Sapienza, Carmen

“…Epidemiological data indicate that children conceived in vitro have a greater relative risk of low birth-weight, major and minor birth defects, and rare…”
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DNA methylation profiling identifies epigenetic differences between diabetes patients with ESRD and diabetes patients without nephropathy by Sapienza, Carmen, Lee, Jean, Powell, Jasmine, Erinle, Oluwatoyin, Yafai, Faahud, Reichert, James, Siraj, Elias S, Madaio, Michael

“…We identified potential epigenetic biomarkers for chronic kidney disease progression by comparing site-specific DNA methylation levels in more than 14,000…”
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Accelerated aging in normal breast tissue of women with breast cancer by Panjarian, Shoghag, Madzo, Jozef, Keith, Kelsey, Slater, Carolyn M, Sapienza, Carmen, Jelinek, Jaroslav, Issa, Jean-Pierre J

“…DNA methylation alterations have similar patterns in normal aging tissue and in cancer. In this study, we investigated breast tissue-specific age-related DNA…”
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Inter- and intra-individual variation in allele-specific DNA methylation and gene expression in children conceived using assisted reproductive technology by Turan, Nahid, Katari, Sunita, Gerson, Leigh F, Chalian, Raffi, Foster, Michael W, Gaughan, John P, Coutifaris, Christos, Sapienza, Carmen

“…Epidemiological studies have reported a higher incidence of rare disorders involving imprinted genes among children conceived using assisted reproductive…”
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Association between gut microbiota and CpG island methylator phenotype in colorectal cancer by Park, Pyoung Hwa, Keith, Kelsey, Calendo, Gennaro, Jelinek, Jaroslav, Madzo, Jozef, Gharaibeh, Raad Z, Ghosh, Jayashri, Sapienza, Carmen, Jobin, Christian, Issa, Jean-Pierre J

“…The intestinal microbiota is an important environmental factor implicated in CRC development. Intriguingly, modulation of DNA methylation by gut microbiota has…”
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DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease? by Turan, Nahid, Ghalwash, Mohamed F, Katari, Sunita, Coutifaris, Christos, Obradovic, Zoran, Sapienza, Carmen

“…Infant birth weight is a complex quantitative trait associated with both neonatal and long-term health outcomes. Numerous studies have been published in which…”
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Explaining inter-individual variability in phenotype: Is epigenetics up to the challenge? by Turan, Nahid, Katari, Sunita, Coutifaris, Christos, Sapienza, Carmen

“…The hypothesis that environmental factors alter somatically heritable epigenetic marks and change long-term patterns of gene expression is an exciting…”
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The epigenetic lorax: gene-environment interactions in human health by Latham, Keith E, Sapienza, Carmen, Engel, Nora

“…Over the last decade, we have witnessed an explosion of information on genetic factors underlying common human diseases and disorders. This 'human genomics'…”
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Epigenetic differences in normal colon mucosa of cancer patients suggest altered dietary metabolic pathways by Silviera, Matthew L, Smith, Brian P, Powell, Jasmine, Sapienza, Carmen

“…We have compared DNA methylation in normal colon mucosa between patients with colon cancer and patients without cancer. We identified significant differences…”
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Female Meiosis Drives Karyotypic Evolution in Mammals by Pardo-Manuel de Villena, Fernando, Sapienza, Carmen

“…Speciation is often accompanied by changes in chromosomal number or form even though such changes significantly reduce the fertility of hybrid intermediates…”
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Unfolded Protein Response Contributes to Preimplantation Mouse Embryo Death in the DDK Syndrome by Hao, Lanping, Vassena, Rita, Wu, Guangming, Han, Zhiming, Cheng, Yong, Latham, Keith E, Sapienza, Carmen

“…DDK syndrome is the polar-lethal embryonic death that occurs at the morula-blastocyst transition when female mice of the DDK strain are mated with males from…”
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Conserved DNA methylation in Gadd45a-/- mice by Engel, Nora, Tront, Jennifer S, Erinle, Toyin, Nguyen, Nghi, Latham, Keith E, Sapienza, Carmen, Hoffman, Barbara, Liebermann, Dan A

“…Gadd45a (growth arrest and DNA-damage-inducible protein 45 alpha) plays a pivotal role in cellular stress responses and is implicated in DNA repair, cell cycle…”
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Epigenetic Drift in Colorectal Cancer-It's Probably Later Than You Think by Sapienza, Carmen

“…The analysis of age-related methylation changes in patients with colorectal cancer indicates that tumors have their origins earlier in life than previously…”
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Human imprinted chromosomal regions are historical hot-spots of recombination by Sandovici, Ionel, Kassovska-Bratinova, Sacha, Vaughan, Joe E, Stewart, Rae, Leppert, Mark, Sapienza, Carmen

“…Human recombination rates vary along the chromosomes as well as between the two sexes. There is growing evidence that epigenetic factors may have an important…”
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Genetic and haplotype diversity among wild-derived mouse inbred strains by Ideraabdullah, Folami Y, de la Casa-Esperón, Elena, Bell, Timothy A, Detwiler, David A, Magnuson, Terry, Sapienza, Carmen, de Villena, Fernando Pardo-Manuel

“…With the completion of the mouse genome sequence, it is possible to define the amount, type, and organization of the genetic variation in this species. Recent…”
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Imprinted Gene Expression, Transplantation Medicine, and the "Other" Human Embryonic Stem Cell by Sapienza, Carmen

“…Two types of embryonic stem cells are potentially useful as sources of therapeutic material in transplantation medicine: EG cells and ES cells. Sapienza…”
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Hybrid Vigor and Transgenerational Epigenetic Effects on Early Mouse Embryo Phenotype by Han, Zhiming, Mtango, Namdori R, Patel, Bela G, Sapienza, Carmen, Latham, Keith E

“…Mouse embryos display a strain-dependent propensity for blastomere cytofragmentation at the two-cell stage. The maternal pronucleus exerts a predominant,…”
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NATURAL SELECTION AND THE EVOLUTION OF GENOME IMPRINTING by de la Casa-Esperón, Elena, Sapienza, Carmen

“…Sexual reproduction results from the fusion of gametes in which the chromatin configuration of maternal and paternal chromosomes is distinct at fertilization…”
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