Search Results - "SANTOSHAM, MATHURAM"

Rotavirus Vaccines — A New Hope by Santosham, Mathuram, Steele, Duncan

“…Rotavirus gastroenteritis is the leading cause of diarrhea-associated hospitalization and death in children younger than 5 years of age, 1 with more than 85%…”
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Rotavirus Vaccine — A Powerful Tool to Combat Deaths from Diarrhea by Santosham, Mathuram

“…Rotavirus infection, the leading cause of severe childhood diarrhea in both developed and developing countries, results in over half a million deaths each…”
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Lung ultrasound for the diagnosis of pneumonia in adults: a systematic review and meta-analysis by Chavez, Miguel A, Shams, Navid, Ellington, Laura E, Naithani, Neha, Gilman, Robert H, Steinhoff, Mark C, Santosham, Mathuram, Black, Robert E, Price, Carrie, Gross, Margaret, Checkley, William

“…Guidelines do not currently recommend the use of lung ultrasound (LUS) as an alternative to chest X-ray (CXR) or chest computerized tomography (CT) scan for…”
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A Systematic Review of Anti-Rotavirus Serum IgA Antibody Titer as a Potential Correlate of Rotavirus Vaccine Efficacy by Patel, Manish, Glass, Roger I., Jiang, Baoming, Santosham, Mathuram, Lopman, Ben, Parashar, Umesh

“…Background. Identifying an immunological correlate of protection for rotavirus vaccines (Rotarix [RV1] and RotaTeq [RV5]) would substantially facilitate…”
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Estimating global, regional and national rotavirus deaths in children aged <5 years: Current approaches, new analyses and proposed improvements by Clark, Andrew, Black, Robert, Tate, Jacqueline, Roose, Anna, Kotloff, Karen, Lam, Diana, Blackwelder, William, Parashar, Umesh, Lanata, Claudio, Kang, Gagandeep, Troeger, Christopher, Platts-Mills, James, Mokdad, Ali, Sanderson, Colin, Lamberti, Laura, Levine, Myron, Santosham, Mathuram, Steele, Duncan

“…Rotavirus is a leading cause of diarrhoeal mortality in children but there is considerable disagreement about how many deaths occur each year. We compared…”
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Molecular mechanism of azithromycin resistance among typhoidal Salmonella strains in Bangladesh identified through passive pediatric surveillance by Hooda, Yogesh, Sajib, Mohammad S I, Rahman, Hafizur, Luby, Stephen P, Bondy-Denomy, Joseph, Santosham, Mathuram, Andrews, Jason R, Saha, Samir K, Saha, Senjuti

“…With the rise in fluoroquinolone-resistant Salmonella Typhi and the recent emergence of ceftriaxone resistance, azithromycin is one of the last oral drugs…”
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Efficacy of motavizumab for the prevention of respiratory syncytial virus disease in healthy Native American infants: a phase 3 randomised double-blind placebo-controlled trial by O'Brien, Katherine L, Prof, Chandran, Aruna, MD, Weatherholtz, Robert, BS, Jafri, Hasan S, MD, Griffin, M Pamela, MD, Bellamy, Terramika, MS, Millar, Eugene V, PhD, Jensen, Kathryn M, MS, Harris, Brian S, MS, Reid, Raymond, MD, Moulton, Lawrence H, PhD, Losonsky, Genevieve A, Karron, Ruth A, Prof, Santosham, Mathuram, Prof

“…Summary Background Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections in children. We aimed to assess the safety…”
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Progress and barriers for the control of diarrhoeal disease by Santosham, Mathuram, Prof, Chandran, Aruna, MD, Fitzwater, Sean, MHS, Fischer-Walker, Christa, MD, Baqui, Abdullah H, Prof, Black, Robert, Prof

“…Summary Discovery of intestinal sodium-glucose transport was the basis for development of oral rehydration solution, and was hailed as potentially the most…”
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Understanding determinants of vaccine hesitancy and acceptance in India: A qualitative study of government officials and civil society stakeholders by Erchick, Daniel J, Gupta, Madhu, Blunt, Madeleine, Bansal, Adarsh, Sauer, Molly, Gerste, Amelia, Holroyd, Taylor A, Wahl, Brian, Santosham, Mathuram, Limaye, Rupali J

“…Few studies have described the drivers of vaccine hesitancy and acceptance in India from the perspective of those involved in the design and implementation of…”
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Product review of the rotavirus vaccines ROTASIIL, ROTAVAC, and Rotavin-M1 by Skansberg, Annika, Sauer, Molly, Tan, Marissa, Santosham, Mathuram, Jennings, Mary Carol

“…Rotavirus is the leading cause of severe dehydrating gastroenteritis and death due to diarrhea among children under 5, causing over 180,000 under-5 deaths…”
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Effect of community-based behaviour change management on neonatal mortality in Shivgarh, Uttar Pradesh, India: a cluster-randomised controlled trial by Kumar, Vishwajeet, MPH, Mohanty, Saroj, MPhil, Kumar, Aarti, MS, Misra, Rajendra P, MA, Santosham, Mathuram, Prof, Awasthi, Shally, Prof, Baqui, Abdullah H, DrPH, Singh, Pramod, MSW, Singh, Vivek, MSW, Ahuja, Ramesh C, Prof, Singh, Jai Vir, Prof, Malik, Gyanendra Kumar, Prof, Ahmed, Saifuddin, PhD, Black, Robert E, Prof, Bhandari, Mahendra, Prof, Darmstadt, Gary L, MD

“…Summary Background In rural India, most births take place in the home, where high-risk care practices are common. We developed an intervention of behaviour…”
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Estimating the global impact of rotavirus vaccines on child mortality by Clark, Andrew, Mahmud, Sarwat, Debellut, Frederic, Pecenka, Clint, Jit, Mark, Perin, Jamie, Tate, Jacqueline, Soeters, Heidi M., Black, Robert E., Santosham, Mathuram, Sanderson, Colin

“…•Rotavirus vaccines prevented around 140,000 child deaths in the period 2006-2019.•Relaxing age restrictions prevented up to 17,000 deaths in the period…”
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Effect of community-based newborn-care intervention package implemented through two service-delivery strategies in Sylhet district, Bangladesh: a cluster-randomised controlled trial by Baqui, Abdullah H, DrPH, El-Arifeen, Shams, DrPH, Darmstadt, Gary L, MD, Ahmed, Saifuddin, PhD, Williams, Emma K, MHS, Seraji, Habibur R, MPH, Mannan, Ishtiaq, MSc, Rahman, Syed M, MDC, Shah, Rasheduzzaman, MSc, Saha, Samir K, PhD, Syed, Uzma, MSc, Winch, Peter J, MD, Lefevre, Amnesty, MHS, Santosham, Mathuram, Prof, Black, Robert E, Prof

“…Summary Background Neonatal mortality accounts for a high proportion of deaths in children under the age of 5 years in Bangladesh. Therefore the project for…”
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The effect of cord cleansing with chlorhexidine on neonatal mortality in rural Bangladesh: a community-based, cluster-randomised trial by Arifeen, Shams El, DrPH, Mullany, Luke C, PhD, Shah, Rasheduzzaman, MBBS, Mannan, Ishtiaq, MBBS, Rahman, Syed M, MBBS, Talukder, M Radwanur R, MBBS, Begum, Nazma, MA, Al-Kabir, Ahmed, PhD, Darmstadt, Gary L, MD, Santosham, Mathuram, Prof, Black, Robert E, Prof, Baqui, Abdullah H, Prof

“…Summary Background Up to half of neonatal deaths in high mortality settings are due to infections, many of which can originate through the freshly cut…”
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Rotavirus Vaccine will Improve Child Survival by More than Just Preventing Diarrhea: Evidence from Bangladesh by Saha, Senjuti, Santosham, Mathuram, Hussain, Manzoor, Black, Robert E, Saha, Samir K

“…Despite the high burden of rotavirus diarrhea, uptake of rotavirus vaccines in Asia remains low. This primarily stems from a perception of rotavirus as a…”
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Hearing loss in Australian First Nations children at 6-monthly assessments from age 12 to 36 months: Secondary outcomes from randomised controlled trials of novel pneumococcal conjugate vaccine schedules by Leach, Amanda Jane, Wilson, Nicole, Arrowsmith, Beth, Beissbarth, Jemima, Mulholland, Kim, Santosham, Mathuram, Torzillo, Paul John, McIntyre, Peter, Smith-Vaughan, Heidi, Skull, Sue A, Oguoma, Victor M, Chatfield, Mark D, Lehmann, Deborah, Brennan-Jones, Christopher G, Binks, Michael J, Licciardi, Paul V, Andrews, Ross M, Snelling, Tom, Krause, Vicki, Carapetis, Jonathan, Chang, Anne B, Morris, Peter Stanley

“…In Australian remote communities, First Nations children with otitis media (OM)-related hearing loss are disproportionately at risk of developmental delay and…”
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Seasonal Drivers of Pneumococcal Disease Incidence: Impact of Bacterial Carriage and Viral Activity by Weinberger, Daniel M., Grant, Lindsay R., Steiner, Claudia A., Weatherholtz, Robert, Santosham, Mathuram, Viboud, Cécile, O’Brien, Katherine L.

“…The drivers of invasive pneumococcal disease seasonality are unknown. We found that pediatric cases with a pneumonia diagnosis peaked in winter and were…”
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Safety and Efficacy of a Pentavalent Human–Bovine (WC3) Reassortant Rotavirus Vaccine by Vesikari, Timo, Matson, David O, Dennehy, Penelope, Van Damme, Pierre, Santosham, Mathuram, Rodriguez, Zoe, Dallas, Michael J, Heyse, Joseph F, Goveia, Michelle G, Black, Steven B, Shinefield, Henry R, Christie, Celia D.C, Ylitalo, Samuli, Itzler, Robbin F, Coia, Michele L, Onorato, Matthew T, Adeyi, Ben A, Marshall, Gary S, Gothefors, Leif, Campens, Dirk, Karvonen, Aino, Watt, James P, O'Brien, Katherine L, DiNubile, Mark J, Clark, H Fred, Boslego, John W, Offit, Paul A, Heaton, Penny M

“…In this randomized trial, the clinical efficacy of an oral, live pentavalent human–bovine reassortant vaccine was estimated to be 98.0 percent against severe…”
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Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies by Siber, George R, Chang, Ih, Baker, Sherryl, Fernsten, Philip, O’Brien, Katherine L, Santosham, Mathuram, Klugman, Keith P, Madhi, Shabir A, Paradiso, Peter, Kohberger, Robert

“…Abstract Estimates of minimum protective antibody concentrations for vaccine preventable diseases are of critical importance in assessing whether new vaccines…”
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Frequency-dependent selection can forecast evolution in Streptococcus pneumoniae by Azarian, Taj, Martinez, Pamela P, Arnold, Brian J, Qiu, Xueting, Grant, Lindsay R, Corander, Jukka, Fraser, Christophe, Croucher, Nicholas J, Hammitt, Laura L, Reid, Raymond, Santosham, Mathuram, Weatherholtz, Robert C, Bentley, Stephen D, O'Brien, Katherine L, Lipsitch, Marc, Hanage, William P

“…Predicting how pathogen populations will change over time is challenging. Such has been the case with Streptococcus pneumoniae, an important human pathogen,…”
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