Search Results - "SANTISTEBAN, MARTA"
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Uncovering functional lncRNAs by scRNA-seq with ELATUS
Published in Nature communications (09-11-2024)“…Long non-coding RNAs (lncRNAs) play fundamental roles in cellular processes and pathologies, regulating gene expression at multiple levels. Despite being…”
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Immune-Induced Epithelial to Mesenchymal Transition In vivo Generates Breast Cancer Stem Cells
Published in Cancer research (Chicago, Ill.) (01-04-2009)“…The breast cancer stem cell (BCSC) hypotheses suggest that breast cancer is derived from a single tumor-initiating cell with stem-like properties, but the…”
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Final results regarding the addition of dendritic cell vaccines to neoadjuvant chemotherapy in early HER2-negative breast cancer patients: clinical and translational analysis
Published in Therapeutic advances in medical oncology (01-12-2021)“…Background: Primary breast cancer (BC) has shown a higher immune infiltration than the metastatic disease, justifying the optimal scenario for immunotherapy…”
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Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer
Published in Frontiers in immunology (02-11-2022)“…Immune checkpoint inhibitor (ICI)-based immunotherapy in triple negative breast cancer (TNBC) is achieving limited therapeutic results, requiring the…”
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Binge Drinking and Risk of Breast Cancer: Results from the SUN ('Seguimiento Universidad de Navarra') Project
Published in Nutrients (10-03-2020)“…Alcohol intake is associated with the risk of breast cancer. Different patterns of alcohol-drinking may have different effects on breast cancer even when…”
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EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth
Published in Journal of hematology and oncology (19-01-2017)“…Activated protein C/endothelial protein C receptor (APC/EPCR) axis is physiologically involved in anticoagulant and cytoprotective activities in endothelial…”
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Multicatheter breast implant during breast conservative surgery: Novel approach to deliver accelerated partial breast irradiation
Published in Brachytherapy (01-07-2016)“…Abstract Purpose To assess the safety, feasibility, and efficacy of free-hand intraoperative multicatheter breast implant (FHIOMBI) and perioperative…”
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Modification of Breast Cancer Milieu with Chemotherapy plus Dendritic Cell Vaccine: An Approach to Select Best Therapeutic Strategies
Published in Biomedicines (17-01-2023)“…The addition of dendritic cell vaccines (DCV) to NAC could induce immune responses in those patients with residual disease (RD) by transforming the tumor…”
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Epidermal Growth Factor Receptor targeting in non-small cell lung cancer: revisiting different strategies against the same target
Published in Current drug targets (01-01-2014)“…Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs) have changed the paradigm of treatment in non-small cell lung cancer (NSCLC). The…”
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Comparative Study of Complications, Logistical Advantages and Control Disease in Match Pair Analysis Between Classical Conservative Approaches Vs. Intraoperative Minimally Invasive Multi-Catheter Breast Implant (IMIMBI) in Early Breast Cancer
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Diagnostic utility of snail in metaplastic breast carcinoma
Published in Diagnostic pathology (26-11-2010)“…Metaplastic breast carcinoma (MBC) is a rare subtype of breast cancer characterized by coexistence of carcinomatous and sarcomatous components. Snail is a…”
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Real-world effectiveness of dual HER2 blockade with pertuzumab and trastuzumab for neoadjuvant treatment of HER2-positive early breast cancer (The NEOPETRA Study)
Published in Breast cancer research and treatment (01-11-2020)“…Purpose Neoadjuvant clinical trials with dual HER2 blockade with pertuzumab and trastuzumab plus chemotherapy demonstrated high rates of pathological complete…”
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Abstract P2-14-11: Immune response monitoring in breast cancer patients treated with neoadjuvant chemotherapy combined with dendritic cell vaccines
Published in Cancer research (Chicago, Ill.) (15-02-2022)“…INTRODUCTION. Breast cancer (BC) is one of the most frequent cancers in women worldwide. Lack of therapeutic efficacy in some BC subtypes makes it necessary to…”
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ABC Transporters as Molecular Effectors of Pancreatic Oncogenic Pathways: The Hedgehog-GLI Model
Published in Journal of gastrointestinal cancer (01-09-2010)“…Introduction Chemoresistance is the main cause of disease progression and mortality among patients diagnosed from pancreatic adenocarcinoma. Nowadays, most…”
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Oxaliplatin plus gemcitabine as a salvage schedule for hormone-refractory prostate adenocarcinoma
Published in Clinical & translational oncology (01-06-2008)“…We report a case of hormone-refractory prostate cancer (HRPC) treated with oxaliplatin plus gemcitabine in a third-line schedule after liver progression, with…”
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Preliminary safety and efficacy of first-line pertuzumab combined with trastuzumab and taxane therapy for HER2-positive locally recurrent or metastatic breast cancer (PERUSE)
Published in Annals of oncology (01-05-2019)“…Pertuzumab combined with trastuzumab and docetaxel is the standard first-line therapy for HER2-positive metastatic breast cancer, based on results from the…”
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Ki67 as a prognostic factor in male breast cancer (male BC): Results from a large GEICAM Spanish cohort of male BC
Published in Journal of clinical oncology (01-06-2024)“…556 Background: Male BC management is based, by default, on evidence produced from female BC. There is a high need to validate gender specific performance of…”
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Body shape trajectories and risk of breast cancer: results from the SUN (‘Seguimiento Universidad De Navarra’) Project
Published in Public health nutrition (01-02-2021)“…The aim of this study was to assess body shape trajectories in childhood and midlife in relation to subsequent risk of breast cancer (BC) in a Mediterranean…”
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Abstract P5-08-04: Physical activity, sedentary behaviour, and risk of breast cancer: Results from the SUN (‘Seguimiento Universidad de Navarra’) project
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…BACKGROUND: Breast cancer is the leading type of cancer in women worldwide. Some factors, like leisure-time physical activity (LTPA), have been inversely…”
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Impact of dendritic cell vaccines added to neoadjuvant CT on pathological complete responses in early breast cancer patients according to PD-L1 expression
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 585 Background: Breast cancer (BC) in early stages exhibit a naïve and competent immune system that translates into a more prominent TIL…”
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