Search Results - "SANON, Nathalie"

Feasibility of implantable iron oxide nanoparticles in detecting brain activity-proof of concept in a rat model by Champagne, Pierre-Olivier, Sanon, Nathalie T., Carmant, Lionel, Pouliot, Philippe, Bouthillier, Alain, Sawan, Mohamad

“…•We investigated a new method of epileptic focus detection using nanoparticles.•Nanoparticles-containing capsules were implanted over the cortex of living…”
Get full text

Early-life stress is associated with gender-based vulnerability to epileptogenesis in rat pups by Desgent, Sébastien, Duss, Sandra, Sanon, Nathalie T, Lema, Pablo, Lévesque, Maxime, Hébert, David, Rébillard, Rose-Marie, Bibeau, Karine, Brochu, Michèle, Carmant, Lionel

“…During development, the risk of developing mesial temporal lobe epilepsy (MTLE) increases when the developing brain is exposed to more than one insult in early…”
Get full text

Superparamagnetic iron oxide nanoparticles-based detection of neuronal activity by Champagne, Pierre-Olivier, Sanon, Nathalie T, Carmant, Lionel, Nguyen, Dang Khoa, Deschênes, Sylvain, Pouliot, Philippe, Bouthillier, Alain, Sawan, Mohamad

“…Precise detection of brain regions harboring heightened electrical activity plays a central role in the understanding and treatment of diseases such as…”
Get full text

Sex differences in the developing brain impact stress-induced epileptogenicity following hyperthermia-induced seizures by Wolf, Daniele C., Desgent, Sébastien, Sanon, Nathalie T., Chen, Jia-Shu, Elkaim, Lior M., Bosoi, Ciprian M., Awad, Patricia N., Simard, Alexe, Salam, Muhammad T., Bilodeau, Guillaume-Alexandre, Duss, Sandra, Sawan, Mohamad, Lewis, Evan C., Weil, Alexander G.

“…Febrile seizures (FS) are common, affecting 2–5% of children between the ages of 3 months and 6 years. Complex FS occur in 10% of patients with FS and are…”
Get full text

Sex-specific differences in KCC2 localisation and inhibitory synaptic transmission in the rat hippocampus by Wolf, Daniele C., Sanon, Nathalie T., Cunha, Alexandra O. S., Chen, Jia-Shu, Shaker, Tarek, Elhassan, Abdul-Rahman, do Nascimento, Antônia Sâmia Fernandes, Di Cristo, Graziella, Weil, Alexander G.

“…Sexual differentiation of the brain is influenced by testosterone and its metabolites during the perinatal period, when many aspects of brain development,…”
Get full text

Decrease of SYNGAP1 in GABAergic cells impairs inhibitory synapse connectivity, synaptic inhibition and cognitive function by Berryer, Martin H., Chattopadhyaya, Bidisha, Xing, Paul, Riebe, Ilse, Bosoi, Ciprian, Sanon, Nathalie, Antoine-Bertrand, Judith, Lévesque, Maxime, Avoli, Massimo, Hamdan, Fadi F., Carmant, Lionel, Lamarche-Vane, Nathalie, Lacaille, Jean-Claude, Michaud, Jacques L., Di Cristo, Graziella

“…Haploinsufficiency of the SYNGAP1 gene, which codes for a Ras GTPase-activating protein, impairs cognition both in humans and in mice. Decrease of Syngap1 in…”
Get full text

Prolongation of Action Potential Duration and QT Interval During Epilepsy Linked to Increased Contribution of Neuronal Sodium Channels to Cardiac Late Na+ Current: Potential Mechanism for Sudden Death in Epilepsy by Biet, Michael, Morin, Nathalie, Lessard-Beaudoin, Melissa, Graham, Rona K, Duss, Sandra, Gagné, Jonathan, Sanon, Nathalie T, Carmant, Lionel, Dumaine, Robert

“…BACKGROUND—Arrhythmias associated with QT prolongation on the ECG often lead to sudden unexpected death in epilepsy. The mechanism causing a prolongation of…”
Get full text

Favorable adverse effect profile of brivaracetam vs levetiracetam in a preclinical model by Sanon, Nathalie T., Gagné, Jonathan, Wolf, Daniele C., Aboulamer, Soumia, Bosoi, Ciprian M., Simard, Alexe, Messiet, Estelle, Desgent, Sébastien, Carmant, Lionel

“…Levetiracetam (LEV), and its newer selective analog brivaracetam (BRV), are two seizure medications that share an innovative mechanism of action targeting the…”
Get full text

Humanized mouse model of Rasmussen's encephalitis supports the immune-mediated hypothesis by Kebir, Hania, Carmant, Lionel, Fontaine, François, Béland, Kathie, Bosoi, Ciprian M, Sanon, Nathalie T, Alvarez, Jorge I, Desgent, Sébastien, Pittet, Camille L, Hébert, David, Langlois, Marie-Josée, Rébillard, Rose-Marie, Nguyen, Dang K, Cieuta-Walti, Cécile, Holmes, Gregory L, Goodkin, Howard P, Mytinger, John R, Connolly, Mary B, Prat, Alexandre, Haddad, Elie

“…Rasmussen's encephalitis (RE) is a chronic inflammatory brain disorder that causes frequent seizures and unilateral hemispheric atrophy with progressive…”
Get full text

Reducing premature KCC2 expression rescues seizure susceptibility and spine morphology in atypical febrile seizures by Awad, Patricia N, Sanon, Nathalie T, Chattopadhyaya, Bidisha, Carriço, Josianne Nunes, Ouardouz, Mohamed, Gagné, Jonathan, Duss, Sandra, Wolf, Daniele, Desgent, Sébastien, Cancedda, Laura, Carmant, Lionel, Di Cristo, Graziella

“…Abstract Atypical febrile seizures are considered a risk factor for epilepsy onset and cognitive impairments later in life. Patients with temporal lobe…”
Get full text

Interneuron subtype specific activation of mGluR1/5 during epileptiform activity in hippocampus by Sanon, Nathalie T, Pelletier, Joe Guillaume, Carmant, Lionel, Lacaille, Jean‐Claude

“…Summary Purpose:  Specific inhibitory interneurons in area CA1 of the hippocampus, notably those located in stratum oriens–alveus (O/A‐INs), are selectively…”
Get full text

Atypical Febrile Seizures, Mesial Temporal Lobe Epilepsy, and Dual Pathology by Sanon, Nathalie T., Desgent, Sébastien, Carmant, Lionel

“…Febrile seizures occurring in the neonatal period, especially when prolonged, are thought to be involved in the later development of mesial temporal lobe…”
Get full text

Short‐term Effects of Kainic Acid on CA1 Hippocampal Interneurons Differentially Vulnerable to Excitotoxicity by Sanon, Nathalie, Carmant, Lionel, Emond, Martine, Congar, Patrice, Lacaille, Jean‐Claude

“…Purpose: We sought to identify the inhibitory interneurons of the rat hippocampal CA1 region selectively vulnerable in the kainic acid (KA) model of temporal…”
Get full text

Behavior of superparamagnetic nanoparticles in regard of brain activity - a proof of concept by Champagne, Pierre-Olivier, Dang Nguyen, Carmant, Lionel, Bouthillier, Alain, Sanon, Nathalie T., Sawan, Mohamad

“…The study of cerebral magnetic activity is very promising for the understanding and care of diseases involving impaired cerebral activity such as epilepsy. One…”
Get full text

Epilepsy Increases the Contribution of Tetrodoxin-Sensitive Channels to the Cardiac Sodium Current by Biet, Michael, Morin, Nathalie, Duss, Sandra, Sanon, Nathalie, Carmant, Lionel, Dumaine, Robert

Get full text

Development and characterization of a novel mouse model of Rasmussen's encephalitis by Fontaine, François, Kebir, Hania, Sanon, Nathalie, Bosoi, Ciprian, Bourbonnière, Lyne, Terouz, Simone, Ciuta, Cecile, Holmes, Gregory L, Goodkin, Howard, Myrtinger, John, Connolly, Mary, Carmant, Lionel, Prat, Alexandre, Haddad, Elie

Get full text

Cell type-specific changes in spontaneous and minimally evoked excitatory synaptic activity in hippocampal CA1 intemeurons of kainate-treated rats by PEREZ, Yaël, RATTE, Stéphanie, SANON, Nathalie, LAPOINTE, Valérie, LACAILLE, Jean-Claude

Get full text

Cell type-specific changes in spontaneous and minimally evoked excitatory synaptic activity in hippocampal CA1 interneurons of kainate-treated rats by Perez, Yaël, Ratté, Stéphanie, Sanon, Nathalie, Lapointe, Valérie, Lacaille, Jean-Claude

“…The epileptiform activity in the kainic acid (KA) model of epilepsy arises from complex changes in excitation and inhibition. To assess the involvement of…”
Get full text