Search Results - "SANKE, T"

Effect of exposure to non-esterified fatty acid on progressive deterioration of insulin secretion in patients with Type 2 diabetes: a long-term follow-up study by Morita, S., Shimajiri, Y., Sakagashira, S., Furuta, M., Sanke, T.

“…Diabet. Med. 29, 980–985 (2012) Aim  The aim of the study was to determine whether fasting serum non‐esterified fatty acid (NEFA) could be associated with…”
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Podocalyxin expression in undifferentiated thyroid carcinomas by Yasuoka, H, Tsujimoto, M, Hirokawa, M, Tori, M, Nakahara, M, Miyauchi, A, Kodama, R, Sanke, T, Nakamura, Y

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Missense mutation of amylin gene (S20G) in Japanese NIDDM patients by Sakagashira, S., Sanke, T., Hanabusa, T., Shimomura, H., Ohagi, S., Kumagaye, K. Y., Nakajima, K., Nanjo, K.

“…Missense mutation of amylin gene (S20G) in Japanese NIDDM patients. S Sakagashira , T Sanke , T Hanabusa , H Shimomura , S Ohagi , K Y Kumagaye , K Nakajima…”
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Single nucleotide polymorphism (D68D, T to C) in the syntaxin 1A gene correlates to age at onset and insulin requirement in Type II diabetic patients by TSUNODA, K, SANKE, T, NAKAGAWA, T, FURUTA, H, NANJO, K

“…Syntaxin 1A is a candidate gene for Type II (non-insulin-dependent) diabetes mellitus, because it plays an important role in insulin secretion from the islet…”
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Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patient with a strong family history by SHIMOMURA, H, SANKE, T, HANABUSA, T, TSUNODA, K, FURUTA, H, NANJO, K

“…Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patient with a strong family history. H Shimomura , T Sanke , T Hanabusa , K Tsunoda , H…”
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Non-autoimmune fulminant type 1 diabetes by Sanke, T

“…A new classification for diabetes mellitus based on ethiology was proposed by the Japan Diabetes Association in 1999. According to the classification, type 1…”
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An islet amyloid peptide is derived from an 89-amino acid precursor by proteolytic processing by Sanke, T, Bell, G I, Sample, C, Rubenstein, A H, Steiner, D F

“…Amyloid deposits occurring in the islets of Langerhans in patients with noninsulin-dependent diabetes mellitus and some insulinomas contain a 37-amino acid…”
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Organization of the human carboxypeptidase E gene and molecular scanning for mutations in Japanese subjects with NIDDM or obesity by UTSUNOMIYA, N, OHAGI, S, SANKE, T, TATSUTA, H, HANABUSA, T, NANJO, K

“…Insulin is synthesized in the pancreatic beta cell as a larger precursor molecule proinsulin which is converted to insulin and C-peptide by the concerted…”
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Enhanced in vitro production of amyloid-like fibrils from mutant (S20G) islet amyloid polypeptide by Ma, Z., Westermark, G. T., Sakagashira, S., Sanke, T., Gustavsson, Å., Sakamoto, H., Engström, U., Nanjo, K., Westermark, P.

“…Islet amyloid polypeptide (IAPP, "amylin") is the amyloid-fibril-forming polypeptide in the islets of Langerhans associated with type 2 diabetes mellitus. A…”
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Plasma islet amyloid polypeptide (Amylin) levels and their responses to oral glucose in type 2 (non-insulin-dependent) diabetic patients by Sanke, T, Hanabusa, T, Nakano, Y, Oki, C, Okai, K, Nishimura, S, Kondo, M, Nanjo, K

“…Fasting plasma islet amyloid polypeptide concentrations and their responses to an oral glucose load were determined in non-diabetic control subjects and…”
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A missense mutation of the muscle glycogen synthase gene (M416V) is associated with insulin resistance in the Japanese population by SHIMOMURA, H, SANKE, T, UEDA, K, HANABUSA, T, SAKAGASHIRA, S, NANJO, K

“…Muscle glycogen synthase (GYS1) is a key enzyme of non-oxidative pathway of glucose metabolism that has been reported to be related to insulin resistance in…”
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Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese by Ohshiro, Y, Sanke, T, Ueda, K, Shimajiri, Y, Nakagawa, T, Tsunoda, K, Nishi, M, Sasaki, H, Takasu, N, Nanjo, K

“…Decreased function of the melanocortin-4 receptor (MC4R) was reported to cause late-onset obesity and insulin resistance in rodents. Thus mutations in the MC4R…”
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Association of the prohormone convertase 2 gene (PCSK2) on chromosome 20 with NIDDM in Japanese subjects by Yoshida, H., Ohagi, S., Sanke, T., Furuta, H., Furuta, M., Nanjo, K.

“…Association of the prohormone convertase 2 gene (PCSK2) on chromosome 20 with NIDDM in Japanese subjects. H Yoshida , S Ohagi , T Sanke , H Furuta , M Furuta…”
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Development of prediction for NIDDM from a view point of genetics by Sanke, T

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Lessons learned from molecular biology of insulin-gene mutations by Steiner, D F, Tager, H S, Chan, S J, Nanjo, K, Sanke, T, Rubenstein, A H

“…Lessons learned from molecular biology of insulin-gene mutations. D F Steiner , H S Tager , S J Chan , K Nanjo , T Sanke and A H Rubenstein Department of…”
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Human prohormone convertase 3 gene: exon-intron organization and molecular scanning for mutations in Japanese subjects with NIDDM by Ohagi, S., Sakaguchi, H., Sanke, T., Tatsuta, H., Hanabusa, T., Nanjo, K.

“…Human prohormone convertase 3 gene: exon-intron organization and molecular scanning for mutations in Japanese subjects with NIDDM. S Ohagi , H Sakaguchi , T…”
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Islet amyloid polypeptide amide causes peripheral insulin resistance in vivo in dogs by SOWA, R, SANKE, T, HIRAYAMA, J, TABATA, H, FURUTA, H, NISHIMURA, S, NANJO, K

“…Islet amyloid polypeptide is a 37 amino acid hormone-like peptide which is the major protein component of islet amyloid deposits commonly found in patients…”
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Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese by OHSHIRO, Y., SANKE, T., UEDA, K., SHIMAJIRI, Y., NAKAGAWA, T., TSUNODA, K., NISHI, M., SASAKI, H., TAKASU, N., NANJO, K.

“…Decreased function of the melanocortin-4 receptor (MC4R) was reported to cause late-onset obesity and insulin resistance in rodents. Thus mutations in the MC4R…”
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Simple tandem repeat DNA polymorphism in the human glycogen synthase gene is associated with NIDDM in Japanese subjects by KUROYAMA, H, SANKE, T, OHAGI, S, FURUTA, M, FURUTA, H, NANJO, K

“…We investigated the possible association between alleles of a simple tandem repeat DNA polymorphism in the human glycogen synthase gene and non-obese…”
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Human prohormone convertase 3 gene : Exon-intron organization and molecular scanning for mutations in Japanese subjects with NIDDM by OHAGI, S, SAKAGUCHI, H, SANKE, T, TATSUTA, H, HANABUSA, T, NANJO, K

“…Proinsulin is converted to insulin by the concerted action of two sequence-specific subtilisin-like proteases termed prohormone convertase 2 (PC2) and…”
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