Search Results - "SANGHVI, Viraj R"

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  1. 1

    The Cellular TAR RNA Binding Protein, TRBP, Promotes HIV-1 Replication Primarily by Inhibiting the Activation of Double-Stranded RNA-Dependent Kinase PKR by SANGHVI, Viraj R, STEEL, Laura F

    Published in Journal of Virology (01-12-2011)
    “…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Journal Article
  2. 2

    A re-examination of global suppression of RNA interference by HIV-1 by Sanghvi, Viraj R, Steel, Laura F

    Published in PloS one (28-02-2011)
    “…The nature of the interaction between replicating HIV-1 and the cellular RNAi pathway has been controversial, but it is clear that it can be complex and…”
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    Journal Article
  3. 3

    The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase by Sanghvi, Viraj R., Leibold, Josef, Mina, Marco, Mohan, Prathibha, Berishaj, Marjan, Li, Zhuoning, Miele, Matthew M., Lailler, Nathalie, Zhao, Chunying, de Stanchina, Elisa, Viale, Agnes, Akkari, Leila, Lowe, Scott W., Ciriello, Giovanni, Hendrickson, Ronald C., Wendel, Hans-Guido

    Published in Cell (08-08-2019)
    “…The NRF2 transcription factor controls a cell stress program that is implicated in cancer and there is great interest in targeting NRF2 for therapy. We show…”
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    Journal Article
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    Interplay of RAP2 GTPase and the cytoskeleton in Hippo pathway regulation by Wu, Chenzhou, Cai, Xiaomin, Wang, Ying, Rodriguez, Carlos D., Zoaldi, Giorgia, Herrmann, Lydia, Huang, Chun-Yuh, Wang, Xiaoqiong, Sanghvi, Viraj R., Lu, Rongze O., Meng, Zhipeng

    Published in The Journal of biological chemistry (01-05-2024)
    “…The Hippo signaling is instrumental in regulating organ size, regeneration, and carcinogenesis. The cytoskeleton emerges as a primary Hippo signaling…”
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    Journal Article
  6. 6

    A Rapid Translational Immune Response Program in CD8 Memory T Lymphocytes by Salloum, Darin, Singh, Kamini, Davidson, Natalie R, Cao, Linlin, Kuo, David, Sanghvi, Viraj R, Jiang, Man, Lafoz, Maria Tello, Viale, Agnes, Ratsch, Gunnar, Wendel, Hans-Guido

    Published in The Journal of immunology (1950) (15-09-2022)
    “…The activation of memory T cells is a very rapid and concerted cellular response that requires coordination between cellular processes in different…”
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    Journal Article
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    NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy by Sanghvi, Viraj R, Mohan, Prathibha, Singh, Kamini, Cao, Linlin, Berishaj, Marjan, Wolfe, Andrew L, Schatz, Jonathan H, Lailler, Nathalie, de Stanchina, Elisa, Viale, Agnes, Wendel, Hans-Guido

    Published in Cancers (05-02-2021)
    “…Inhibition of the eIF4A RNA helicase with silvestrol and related compounds is emerging as a powerful anti-cancer strategy. We find that a synthetic silvestrol…”
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    Journal Article
  10. 10

    Frequent 4EBP1 Amplification Induces Synthetic Dependence on FGFR Signaling in Cancer by Mohan, Prathibha, Pasion, Joyce, Ciriello, Giovanni, Lailler, Nathalie, de Stanchina, Elisa, Viale, Agnes, van den Berg, Anke, Diepstra, Arjan, Wendel, Hans-Guido, Sanghvi, Viraj R, Singh, Kamini

    Published in Cancers (13-05-2022)
    “…The eIF4E translation initiation factor has oncogenic properties and concordantly, the inhibitory eIF4E-binding protein (4EBP1) is considered a tumor…”
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    Journal Article
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    RNA silencing as a cellular defense against HIV‐1 infection: progress and issues by Sanghvi, Viraj R., Steel, Laura F.

    Published in The FASEB journal (01-10-2012)
    “…MicroRNAs (miRNAs) are known to have a role in gene regulation that is closely integrated into the pathways that control virtually all fundamental cell…”
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    Journal Article
  13. 13
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    Expression of interfering RNAs from an HIV-1 Tat-inducible chimeric promoter by Sanghvi, Viraj R., Steel, Laura F.

    Published in Virus research (2011)
    “…The therapeutic value of antiviral interfering RNAs could be improved by technologies that limit their expression to the infected cell population. The HIV-1…”
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    Journal Article
  15. 15

    Polycistronic expression of interfering RNAs from RNA polymerase III promoters by Steel, Laura F, Sanghvi, Viraj R

    “…In many RNA silencing applications, there is a benefit to expressing multiple interfering RNAs simultaneously. This can be achieved by using a single RNA…”
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    Journal Article
  16. 16

    Abstract 878: Frequent 4EBP1 amplification induces synthetic dependence on FGFR signaling in cancer by Singh, Kamini, Mohan, Prathibha, Sanghvi, Viraj R., Ciriello, Giovanni, Lailler, Nathalie, de Stanchina, Elisa, Wendel, Hans-Guido

    Published in Cancer research (Chicago, Ill.) (15-06-2022)
    “…The eIF4E translation initiation factor has oncogenic properties and concordantly, the inhibitory eIF4E-binding protein (4EBP1) is considered a tumor…”
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    Journal Article
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    Interactions between HIV-1 and host cell RNAi pathways and the characterization of a conditional promoter for use in RNAi-based anti-HIV-1 therapeutics by Sanghvi, Viraj R

    Published 01-01-2011
    “…RNA interference is an evolutionarily conserved mechanism of gene regulation with a role in antiviral defense in invertebrates. It has been of interest to…”
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    Dissertation
  19. 19

    Interactions between HIV-1 and host cell RNAi pathways and the characterization of a conditional promoter for use in RNAi-based anti-HIV-1 therapeutics by Sanghvi, Viraj R

    “…RNA interference is an evolutionarily conserved mechanism of gene regulation with a role in antiviral defense in invertebrates. It has been of interest to…”
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    Dissertation