Search Results - "SANDSTRÖM, Mattias"

Measuring HER2-Receptor Expression In Metastatic Breast Cancer Using [68Ga]ABY-025 Affibody PET/CT by Sörensen, Jens, Velikyan, Irina, Sandberg, Dan, Wennborg, Anders, Feldwisch, Joachim, Tolmachev, Vladimir, Orlova, Anna, Sandström, Mattias, Lubberink, Mark, Olofsson, Helena, Carlsson, Jörgen, Lindman, Henrik

“…Positron Emission Tomography (PET) imaging of HER2 expression could potentially be used to select patients for HER2-targed therapy, predict response based on…”
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Kidney dosimetry in 777 patients during 177Lu-DOTATATE therapy: aspects on extrapolations and measurement time points by Sandström, Mattias, Freedman, Nanette, Fröss-Baron, Katarzyna, Kahn, Tanweera, Sundin, Anders

“…Purpose Fractionated peptide receptor radionuclide therapy (PRRT) with 177 Lu-DOTATATE is increasingly applied as an effective treatment for patients with…”
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Synthetic affibody molecules : A novel class of affinity ligands for molecular imaging of HER2-expressing malignant tumors by ORLOVA, Anna, TOLMACHEV, Vladimir, PEHRSON, Rikard, LINDBORG, Malin, TRAN, Thuy, SANDSTRÖM, Mattias, NILSSON, Fredrik Y, WENNBORG, Anders, ABRAHMSEN, Lars, FELDWISCH, Joachim

“…The Affibody molecule Z(HER2:342-pep2), site-specifically and homogeneously conjugated with a 1,4,7,10-tetra-azacylododecane-N,N',N'',N'''-tetraacetic acid…”
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Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors by Honarvar, Hadis, Westerlund, Kristina, Altai, Mohamed, Sandström, Mattias, Orlova, Anna, Tolmachev, Vladimir, Karlström, Amelie Eriksson

“…Affibody molecules are small (7 kDa), non-immunoglobulin scaffold proteins with a potential as targeting agents for radionuclide imaging of cancer. However,…”
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Variations in the practice of molecular radiotherapy and implementation of dosimetry: results from a European survey by Sjögreen Gleisner, Katarina, Spezi, Emiliano, Solny, Pavel, Gabina, Pablo Minguez, Cicone, Francesco, Stokke, Caroline, Chiesa, Carlo, Paphiti, Maria, Brans, Boudewijn, Sandström, Mattias, Tipping, Jill, Konijnenberg, Mark, Flux, Glenn

“…Background Currently, the implementation of dosimetry in molecular radiotherapy (MRT) is not well investigated, and in view of the Council Directive…”
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Personalized radiation dosimetry for PRRT—how many scans are really required? by Freedman, Nanette, Sandström, Mattias, Kuten, Jonathan, Shtraus, Natan, Ospovat, Inna, Schlocker, Albert, Even-Sapir, Einat

“…Purpose Over recent years, peptide receptor radiotherapy (PRRT) has been recognized as an effective treatment for patients with metastatic neuroendocrine…”
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Dosimetry-based treatment planning for molecular radiotherapy: a summary of the 2017 report from the Internal Dosimetry Task Force by Stokke, Caroline, Gabiña, Pablo Minguez, Solný, Pavel, Cicone, Francesco, Sandström, Mattias, Gleisner, Katarina Sjögreen, Chiesa, Carlo, Spezi, Emiliano, Paphiti, Maria, Konijnenberg, Mark, Aldridge, Matt, Tipping, Jill, Wissmeyer, Michael, Brans, Boudewijn, Bacher, Klaus, Kobe, Carsten, Flux, Glenn

“…Background The European directive on basic safety standards (Council directive 2013/59 Euratom) mandates dosimetry-based treatment planning for…”
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Results from an EANM survey on time estimates and personnel responsible for main tasks in molecular radiotherapy dosimetry by Gabiña, Pablo Mínguez, Gleisner, Katarina Sjögreen, Cremonesi, Marta, Stokke, Caroline, Flux, Glenn, Cicone, Francesco, Konijnenberg, Mark, Aldridge, Matt, Sandstrom, Mattias, Chiesa, Carlo, Paphiti, Maria, Hippeläinen, Eero, Uribe, Carlos, Solny, Pavel, Gnesin, Silvano, Bernhardt, Peter, Chouin, Nicolas, Costa, Pedro Fragoso, Glatting, Gerhard, Verburg, Frederik, Gear, Jonathan

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Impact of administered amount of peptide on tumor dosimetry at the first cycle of peptide receptor radionuclide therapy (PRRT) in relation to total tumor somatostatin receptor expression by Jahn, Ulrika, Garske-Román, Ulrike, Sandström, Mattias, Lubberink, Mark, Sundin, Anders

“…Background The accumulation of 177 Lu-DOTATATE might be influenced by the amount of administered peptide in relation to the tumor somatostatin receptor…”
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Design, synthesis and biological evaluation of a multifunctional HER2-specific Affibody molecule for molecular imaging by Tran, Thuy A., Rosik, Daniel, Abrahmsén, Lars, Sandström, Mattias, Sjöberg, Anna, Wållberg, Helena, Ahlgren, Sara, Orlova, Anna, Tolmachev, Vladimir

“…Purpose The purpose of this study was to design and evaluate a novel platform for labelling of Affibody molecules, enabling both recombinant and synthetic…”
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Quantitative and qualitative intrapatient comparison of 68Ga-DOTATOC and 68Ga-DOTATATE: net uptake rate for accurate quantification by Velikyan, Irina, Sundin, Anders, Sörensen, Jens, Lubberink, Mark, Sandström, Mattias, Garske-Román, Ulrike, Lundqvist, Hans, Granberg, Dan, Eriksson, Barbro

“…Quantitative imaging and dosimetry are crucial for individualized treatment during peptide receptor radionuclide therapy (PRRT). (177)Lu-DOTATATE and…”
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First-in-Human Molecular Imaging of HER2 Expression in Breast Cancer Metastases Using the 111 In-ABY-025 Affibody Molecule by Sörensen, Jens, Sandberg, Dan, Sandström, Mattias, Wennborg, Anders, Feldwisch, Joachim, Tolmachev, Vladimir, Åström, Gunnar, Lubberink, Mark, Garske-Román, Ulrike, Carlsson, Jörgen, Lindman, Henrik

“…The expression status of human epidermal growth factor receptor type 2 (HER2) predicts the response of HER2-targeted therapy in breast cancer. ABY-025 is a…”
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Individualized dosimetry of kidney and bone marrow in patients undergoing 177Lu-DOTA-octreotate treatment by Sandström, Mattias, Garske-Román, Ulrike, Granberg, Dan, Johansson, Silvia, Widström, Charles, Eriksson, Barbro, Sundin, Anders, Lundqvist, Hans, Lubberink, Mark

“…The organs at risk in radionuclide therapy with (177)Lu-octreotate are the bone marrow and the kidneys. The primary aim of this study was to develop an…”
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Phase I Study of 99mTc-ADAPT6, a Scaffold Protein–Based Probe for Visualization of HER2 Expression in Breast Cancer by Bragina, Olga, von Witting, Emma, Garousi, Javad, Zelchan, Roman, Sandström, Mattias, Orlova, Anna, Medvedeva, Anna, Doroshenko, Artem, Vorobyeva, Anzhelika, Lindbo, Sarah, Borin, Jesper, Tarabanovskaya, Natalya, Sörensen, Jens, Hober, Sophia, Chernov, Vladimir, Tolmachev, Vladimir

“…Radionuclide molecular imaging of human epidermal growth factor receptor type 2 (HER2) expression may help to stratify breast and gastroesophageal cancer…”
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Comparative Biodistribution and Radiation Dosimetry of Ga-68-DOTATOC and Ga-68-DOTATATE in Patients with Neuroendocrine Tumors by Sandström, Mattias, Velikyan, Irina, Garske-Roman, Ulrike, Sörensen, Jens, Eriksson, Barbro, Granberg, Dan, Lundqvist, Hans, Sundin, Anders, Lubberink, Mark

“…Ga-68-DOTATOC and Ga-68-DOTATATE are 2 radiolabeled somatostatin analogs for in vivo diagnosis of neuroendocrine tumors with PET. The aim of the present work…”
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Biodistribution and Radiation Dosimetry of the Anti-HER2 Affibody Molecule Ga-68-ABY-025 in Breast Cancer Patients by Sandström, Mattias, Lindskog, Karolina, Velikyan, Irma, Wennborg, Anders, Feldwisch, Joachim, Sandberg, Dan, Tolmachev, Vladimir, Orlova, Anna, Sörensen, Jens, Carlsson, Jörgen, Lindman, Henrik, Lubberink, Mark

“…Ga-68-ABY-025 is a radiolabeled Affibody molecule for in vivo diagnosis of human epidermal growth factor receptor 2 (HER2)-positive breast cancer tumors with…”
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Individualized dosimetry in patients undergoing therapy with Lu-177-DOTA-D-Phe(1)-Tyr(3)-octreotate by Sandström, Mattias, Garske, Ulrike, Granberg, Dan, Sundin, Anders, Lundqvist, Hans

“…In recent years, targeted radionuclide therapy with [Lu-177-DOTA(0), Tyr(3)]octreotate for neuroendocrine tumours has yielded promising results. This therapy…”
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Synthesis and Characterization of a High-Affinity NOTA-Conjugated Bombesin Antagonist for GRPR-Targeted Tumor Imaging by Varasteh, Zohreh, Velikyan, Irina, Lindeberg, Gunnar, Sörensen, Jens, Larhed, Mats, Sandström, Mattias, Selvaraju, Ram Kumar, Malmberg, Jennie, Tolmachev, Vladimir, Orlova, Anna

“…The gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for the visualization of prostate cancer. This work focused on the development of…”
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Radionuclide therapy of HER2-positive microxenografts using a 177Lu-labeled HER2-specific affibody molecule by TOLMACHEV, Vladimir, ORLOVA, Anna, WENNBORG, Anders, NILSSON, Fredrik Y, PEHRSON, Rikard, GALLI, Joakim, BAASTRUP, Barbro, ANDERSSON, Karl, SANDSTRÖM, Mattias, ROSIK, Daniel, CARLSSON, Jörgen, LUNDQVIST, Hans

“…A radiolabeled anti-HER2 Affibody molecule (Z(HER2:342)) targets HER2-expressing xenografts with high selectivity and gives good imaging contrast. However, the…”
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ADAPT, a Novel Scaffold Protein-Based Probe for Radionuclide Imaging of Molecular Targets That Are Expressed in Disseminated Cancers by Garousi, Javad, Lindbo, Sarah, Nilvebrant, Johan, Åstrand, Mikael, Buijs, Jos, Sandström, Mattias, Honarvar, Hadis, Orlova, Anna, Tolmachev, Vladimir, Hober, Sophia

“…Small engineered scaffold proteins have attracted attention as probes for radionuclide-based molecular imaging. One class of these imaging probes, termed…”
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