Search Results - "SANDRASAGRA, Anthony"

Stromal cell-derived factor-1 retention and cardioprotection for ischemic myocardium by Kanki, Sachiko, Segers, Vincent F M, Wu, Weitao, Kakkar, Rahul, Gannon, Joseph, Sys, Stanislas U, Sandrasagra, Anthony, Lee, Richard T

“…Stromal cell-derived factor-1 (SDF-1) is a chemoattractant of stem/progenitor cells, and several studies have shown that SDF-1 may improve ventricular function…”
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Protease-Resistant Stromal Cell―Derived Factor-1 for the Treatment of Experimental Peripheral Artery Disease by SEGERS, Vincent F. M, REVIN, Vyacheslav, WEITAO WU, HELEN QIU, ZHENG YAN, LEE, Richard T, SANDRASAGRA, Anthony

“…Peripheral artery disease is a potentially incapacitating disease for which pharmacological options are limited. Stromal cell-derived factor-1 (SDF-1) is a…”
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Dust mite-induced asthma in cynomolgus monkeys by Van Scott, Michael R, Hooker, Jerry L, Ehrmann, David, Shibata, Yoshimi, Kukoly, Cynthia, Salleng, Kenneth, Westergaard, Greg, Sandrasagra, Anthony, Nyce, Jonathan

“…Departments of 1 Physiology, 2 Medicine, and 3 Comparative Medicine, East Carolina University, Greenville, North Carolina 27858; 4 LABS of Virginia c ,…”
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Abstract TP211: Recombinant Growth Differentiation Factor 11 Treatment Improves Functional Outcome In A Rat Permanent Ischemia Model Of Subacute Stroke by Paskavitz, James, Wang, Yongting, Sinha, Manisha, Cohen, Ori, Daman, Tyler, Deatherage, Catherine, Jordan, Samuel, Li, Pi-Chun, Allen, Mark, Sandrasagra, Anthony

“…IntroductionGDF11 is a pleiotropic circulating blood factor and member of the transforming growth factor β (TGFβ) superfamily. In animal models of stroke,…”
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Absorption, distribution, metabolism, and excretion of a respirable antisense oligonucleotide for asthma by ALI, Shahid, LEONARD, Sherry A, KUKOLY, Cindy A, METZGER, W. James, WOOLES, Wallace R, MCGINTY, Jacqueline F, TANAKA, Makoto, SANDRASAGRA, Anthony, NYCE, Jonathan W

“…EPI-2010 is a respirable antisense oligonucleotide (RASON), which selectively attenuates discordantly overexpressed adenosine A(1) receptors in allergic lung…”
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Iloperidone binding to human and rat dopamine and 5-HT receptors by Kongsamut, Sathapana, Roehr, Joachim E, Cai, Jidong, Hartman, Harold B, Weissensee, Paul, Kerman, Lisa L, Tang, Lei, Sandrasagra, Anthony

“…Iloperidone (HP 873; 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]ethanone) is a compound currently in clinical trials…”
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Clinical potential of respirable antisense oligonucleotides (RASONs) in asthma by Ball, Howard A, Sandrasagra, Anthony, Tang, Lei, Van Scott, Mike, Wild, James, Nyce, Jonathan W

“…The human genome project, as well as advances in our understanding of asthma susceptibility, are yielding novel candidate targets for disease intervention. The…”
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RASONs: a novel antisense oligonucleotide therapeutic approach for asthma by Sandrasagra, A, Tang, L, Leonard, S A, Teng, K, Li, Y, Mannion, J C, Nyce, J W

“…Inhalation based approaches enable the local delivery of antisense oligonucleotides (ASONs) to the respiratory tract and thus facilitate the ability of ASONs…”
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Phage display of functional human TNF-alpha converting enzyme catalytic domain: a rapid method for the production of stabilized proteolytic proteins for assay development and high-throughput screening by Chen, Yangde, Diener, Katrina, Patel, Indravadan R, Kawooya, John K, Martin, Gary A, Yamdagni, Preeti, Zhang, Xin, Sandrasalphaa, Anthony, Sahasrabudhe, Sudhir, Busch, Steven J

“…The catalytic domain of human tumor necrosis factor-alpha (TNF-alpha) converting enzyme (TACE) was expressed in a phage display system to determine whether…”
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Regulation of murine glutamine synthetase expression in rodent tissue culture cells by Sandrasagra, Anthony

“…Glutamine synthetase (GS) plays a central role in nitrogen metabolism and is involved in the metabolism of ammonia, glutamic acid and $\gamma$-amino butyric…”
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Rat-1 fibroblasts engineered with GAD65 and GAD67 cDNAs in retroviral vectors produce and release GABA by Ruppert, C, Sandrasagra, A, Anton, B, Evans, C, Schweitzer, E S, Tobin, A J

“…We have used a retroviral cDNA expression system to drive the expression of the different forms of glutamic acid decarboxylase (GAD65, GAD67, or both)…”
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Multiple mechanisms by which glutamine synthetase levels are controlled in murine tissue culture cells by Sandrasagra, A, Patejunas, G, Young, A P

“…We report the isolation of a complimentary DNA (cDNA) clone encoding glutamine synthetase, derived from a population of methionine sulfoxime-resistant mouse…”
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Discovery and development of respirable antisense therapeutics for asthma by Sandrasagra, Anthony, Leonard, Sherry A, Tang, Lei, Teng, Kelly, Li, Yukui, Ball, Howard A, Mannion, James C, Nyce, Jonathan W

“…Respirable antisense oligonucleotides (RASONs) represent a novel class of respiratory therapeutic molecules with the potential to specifically address the…”
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