Search Results - "SANDRA, Koen"

Chromatographic, Electrophoretic, and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals by Fekete, Szabolcs, Guillarme, Davy, Sandra, Pat, Sandra, Koen

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Modern chromatographic and mass spectrometric techniques for protein biopharmaceutical characterization by Sandra, Koen, Vandenheede, Isabel, Sandra, Pat

“…•Protein biopharmaceuticals are highly complex and heterogeneous macromolecules.•Chromatography and MS are at the forefront in protein…”
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Profiling and Characterizing Skin Ceramides Using Reversed-Phase Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry by t’Kindt, Ruben, Jorge, Lucie, Dumont, Emmie, Couturon, Pauline, David, Frank, Sandra, Pat, Sandra, Koen

“…An LC-MS based method for the profiling and characterization of ceramide species in the upper layer of human skin is described. Ceramide samples, collected by…”
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Comprehensive blood plasma lipidomics by liquid chromatography/quadrupole time-of-flight mass spectrometry by Sandra, Koen, Pereira, Alberto dos Santos, Vanhoenacker, Gerd, David, Frank, Sandra, Pat

“…A lipidomics strategy, combining high resolution reversed-phase liquid chromatography (RPLC) with high resolution quadrupole time-of-flight mass spectrometry…”
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Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors by Hale, Geoff, De Vos, Jelle, Davy, Alastair Douglas, Sandra, Koen, Wilkinson, Ian

“…Elimination of the binding of immunoglobulin Fc to Fc gamma receptors is highly desirable for the avoidance of unwanted inflammatory responses to therapeutic…”
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The opportunities of 2D-LC in the analysis of monoclonal antibodies by Sandra, Koen, Sandra, Pat

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Quantitative N-Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMS Analysis by Duivelshof, Bastiaan L., Denorme, Steffy, Sandra, Koen, Liu, Xiaoxiao, Beck, Alain, Lauber, Matthew A., Guillarme, Davy, D’Atri, Valentina

“…The identification and accurate quantitation of the various glycoforms contained in therapeutic monoclonal antibodies (mAbs) is one of the main analytical…”
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Multimodal biomarker discovery for active Onchocerca volvulus infection by Lagatie, Ole, Njumbe Ediage, Emmanuel, Van Roosbroeck, Dirk, Van Asten, Stijn, Verheyen, Ann, Batsa Debrah, Linda, Debrah, Alex, Odiere, Maurice R, T'Kindt, Ruben, Dumont, Emmie, Sandra, Koen, Dillen, Lieve, Verhaeghe, Tom, Vreeken, Rob, Cuyckens, Filip, Stuyver, Lieven J

“…The neglected tropical disease onchocerciasis, or river blindness, is caused by infection with the filarial nematode Onchocerca volvulus. Current estimates…”
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2-Methyl-pentanoyl-carnitine (2-MPC): a urine biomarker for patent Ascaris lumbricoides infection by Lagatie, Ole, Verheyen, Ann, Van Asten, Stijn, Odiere, Maurice R., Djuardi, Yenny, Levecke, Bruno, Vlaminck, Johnny, Mekonnen, Zeleke, Dana, Daniel, T’Kindt, Ruben, Sandra, Koen, van Outersterp, Rianne, Oomens, Jos, Lin, Ronghui, Dillen, Lieve, Vreeken, Rob, Cuyckens, Filip, Stuyver, Lieven J.

“…Infections with intestinal worms, such as Ascaris lumbricoides, affect hundreds of millions of people in all tropical and subtropical regions of the world…”
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Highly efficient peptide separations in proteomics Part 2: Bi-and multidimensional liquid-based separation techniques by SANDRA, Koen, MOSHIR, Mahan, D'HONDT, Filip, TUYTTEN, Robin, VERLEYSEN, Katleen, KAS, Koen, FRANCOIS, Isabelle, SANDRA, Pat

“…Multidimensional liquid-based separation techniques are described for maximizing the resolution of the enormous number of peptides generated upon tryptic…”
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Highly efficient peptide separations in proteomics Part 1. Unidimensional high performance liquid chromatography by SANDRA, Koen, MOSHIR, Mahan, D'HONDT, Filip, VERLEYSEN, Katleen, KAS, Koen, SANDRA, Pat

“…Sample complexity and dynamic range constitute enormous challenges in proteome analysis. The back-end technology in typical proteomics platforms, namely mass…”
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Exploring the Possibilities of Cryogenic Cooling in Liquid Chromatography for Biological Applications: A Proof of Principle by Eghbali, Hamed, Sandra, Koen, Tienpont, Bart, Eeltink, Sebastiaan, Sandra, Pat, Desmet, Gert

“…The possibilities to use cryogenic cooling to trap components in liquid chromatography was investigated. In a first step, van ‘t Hoff plots were measured with…”
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Determination of variability due to biological and technical variation in urinary extracellular vesicles as a crucial step in biomarker discovery studies by Oeyen, Eline, Willems, Hanny, 'T Kindt, Ruben, Sandra, Koen, Boonen, Kurt, Hoekx, Lucien, De Wachter, Stefan, Ameye, Filip, Mertens, Inge

“…Urinary extracellular vesicles (EVs) are an attractive source of biomarkers for urological diseases. A crucial step in biomarker discovery studies is the…”
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Performance evaluation of long monolithic silica capillary columns in gradient liquid chromatography using peptide mixtures by Eghbali, Hamed, Sandra, Koen, Detobel, Frederik, Lynen, Frederic, Nakanishi, Kazuki, Sandra, Pat, Desmet, Gert

“…A systematic study is reported on the performance of long monolithic capillary columns in gradient mode. Using a commercial nano-LC system, reversed-phase…”
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Innovative patient education and pain management protocols to achieve opioid-free shoulder arthroplasty by Sabesan, Vani J., Chatha, Kiran, Koen, Sandra, Dawoud, Mirelle, Gilot, Gregory

“…The creation of pain as the fifth vital sign led to skyrocketing opioid prescriptions and a crisis with addiction and abuse among Americans. The purpose of…”
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Critical role of aldehydes in cigarette smoke-induced acute airway inflammation by van der Toorn, Marco, Slebos, Dirk-Jan, de Bruin, Harold G, Gras, Renee, Rezayat, Delaram, Jorge, Lucie, Sandra, Koen, van Oosterhout, Antoon J M

“…Cigarette smoking (CS) is the most important risk factor for COPD, which is associated with neutrophilic airway inflammation. We hypothesize, that highly…”
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What do patients think about opioids? a survey of patient perceptions regarding pain control after shoulder surgery by Sabesan, Vani, Dawoud, Mirelle, Chatha, Kiran, Koen, Sandra, Khoury, Laila

“…There is an increasing need to understand what barriers are present to reduce opioid consumption in orthopedic practice. The purpose of this study was to…”
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An integrated educational and multimodal approach to achieving an opioid-free postoperative course after arthroscopic rotator cuff repair by Sabesan, Vani J., Chatha, Kiran, Koen, Sandra, Echeverry, Nikolas, Borroto, Wilfredo J., Khoury, Laila H., Stephens, B. Joshua, Gilot, Gregory

“…In the realm of shoulder surgery, arthroscopic rotator cuff repair (RCR) is one of the most painful procedures and is often associated with higher opioid…”
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New insights in Rapana venosa hemocyanin N-glycosylation resulting from on-line mass spectrometric analyses by Sandra, Koen, Dolashka-Angelova, Pavlina, Devreese, Bart, Van Beeumen, Jozef

“…The N-glycosylation of structural unit 1 of Rapana venosa hemocyanin was studied. Enzymatically liberated N-glycans were analyzed by matrix-assisted laser…”
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Factors influencing glycosylation of Trichoderma reesei cellulases. I: Postsecretorial changes of the O- and N-glycosylation pattern of Cel7A by Stals, Ingeborg, Sandra, Koen, Geysens, Steven, Contreras, Roland, Van Beeumen, Jozef, Claeyssens, Marc

“…The glycosylation of Cel7A (CBH I) from Trichoderma reesei varies considerably when the fungus is grown under different conditions. As shown by ESI-MS and…”
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