Search Results - "SANDINI, Silvia"

Innate Immune Response to SARS-CoV-2 Infection: From Cells to Soluble Mediators by Ricci, Daniela, Etna, Marilena Paola, Rizzo, Fabiana, Sandini, Silvia, Severa, Martina, Coccia, Eliana Marina

“…The vulnerability of humankind to SARS-CoV-2 in the absence of a pre-existing immunity, the unpredictability of the infection outcome, and the high…”
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Co-Infections and Superinfections between HIV-1 and Other Human Viruses at the Cellular Level by Acchioni, Chiara, Sandini, Silvia, Acchioni, Marta, Sgarbanti, Marco

“…Co-infection or superinfection of the host by two or more virus species is a common event, potentially leading to viral interference, viral synergy, or neutral…”
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Fighting HIV-1 Persistence: At the Crossroads of “Shoc-K and B-Lock” by Acchioni, Chiara, Palermo, Enrico, Sandini, Silvia, Acchioni, Marta, Hiscott, John, Sgarbanti, Marco

“…Despite the success of highly active antiretroviral therapy (HAART), integrated HIV-1 proviral DNA cannot be eradicated from an infected individual. HAART is…”
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The MP65 gene is required for cell wall integrity, adherence to epithelial cells and biofilm formation in Candida albicans by Sandini, Silvia, Stringaro, Annarita, Arancia, Silvia, Colone, Marisa, Mondello, Francesca, Murtas, Susanna, Girolamo, Antonietta, Mastrangelo, Nicolina, De Bernardis, Flavia

“…The MP65 gene of Candida albicans (orf19.1779) encodes a putative β-glucanase mannoprotein of 65 kDa, which plays a main role in a host-fungus relationship,…”
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Differential Responses of Human Dendritic Cells to Live or Inactivated Staphylococcus aureus : Impact on Cytokine Production and T Helper Expansion by Cruciani, Melania, Sandini, Silvia, Etna, Marilena P, Giacomini, Elena, Camilli, Romina, Severa, Martina, Rizzo, Fabiana, Bagnoli, Fabio, Hiscott, John, Coccia, Eliana M

“…Understanding ( )-host immune system interaction is crucial to meet the tremendous medical need associated with this life-threatening bacterial infection…”
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Isolation and Characterization of Mouse Monoclonal Antibodies That Neutralize SARS-CoV-2 and Its Variants of Concern Alpha, Beta, Gamma and Delta by Binding Conformational Epitopes of Glycosylated RBD With High Potency by Mariotti, Sabrina, Capocefalo, Antonio, Chiantore, Maria Vincenza, Iacobino, Angelo, Teloni, Raffaela, De Angelis, Maria Laura, Gallinaro, Alessandra, Pirillo, Maria Franca, Borghi, Martina, Canitano, Andrea, Michelini, Zuleika, Baggieri, Melissa, Marchi, Antonella, Bucci, Paola, McKay, Paul F, Acchioni, Chiara, Sandini, Silvia, Sgarbanti, Marco, Tosini, Fabio, Di Virgilio, Antonio, Venturi, Giulietta, Marino, Francesco, Esposito, Valeria, Di Bonito, Paola, Magurano, Fabio, Cara, Andrea, Negri, Donatella, Nisini, Roberto

“…Antibodies targeting Receptor Binding Domain (RBD) of SARS-CoV-2 have been suggested to account for the majority of neutralizing activity in COVID-19…”
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Modular structure of HEL protein from Arabidopsis reveals new potential functions for PR-4 proteins by Bertini, Laura, Proietti, Silvia, Aleandri, Maria Pia, Mondello, Francesca, Sandini, Silvia, Caporale, Carlo

“…Plants possess an innate immune system enabling them to defend themselves against pathogen attack. The accumulation of newly synthesized pathogenesis-related…”
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Staphylococcus aureus Esx Factors Control Human Dendritic Cell Functions Conditioning Th1/Th17 Response by Cruciani, Melania, Etna, Marilena P, Camilli, Romina, Giacomini, Elena, Percario, Zulema A, Severa, Martina, Sandini, Silvia, Rizzo, Fabiana, Brandi, Valentina, Balsamo, Giuliana, Polticelli, Fabio, Affabris, Elisabetta, Pantosti, Annalisa, Bagnoli, Fabio, Coccia, Eliana M

“…The opportunistic pathogen ( ) is a major cause of nosocomial- and community-acquired infections. In addition, many antibiotic-resistant strains are emerging…”
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New Monoclonal Antibodies Specific for Different Epitopes of the Spike Protein of SARS-CoV-2 and Its Major Variants: Additional Tools for a More Specific COVID-19 Diagnosis by Mariotti, Sabrina, Chiantore, Maria Vincenza, Teloni, Raffaela, Iacobino, Angelo, Capocefalo, Antonio, Michelini, Zuleika, Borghi, Martina, Baggieri, Melissa, Marchi, Antonella, Bucci, Paola, Gioacchini, Silvia, D'Amelio, Raffaele, Brouwer, Philip J M, Sandini, Silvia, Acchioni, Chiara, Sgarbanti, Marco, Di Virgilio, Antonio, Grasso, Felicia, Cara, Andrea, Negri, Donatella, Magurano, Fabio, Di Bonito, Paola, Nisini, Roberto

“…The emergence of the new pathogen SARS-CoV-2 determined a rapid need for monoclonal antibodies (mAbs) to detect the virus in biological fluids as a rapid tool…”
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Candida albicans OPI1 regulates filamentous growth and virulence in vaginal infections, but not inositol biosynthesis by Chen, Ying-Lien, de Bernardis, Flavia, Yu, Shang-Jie, Sandini, Silvia, Kauffman, Sarah, Tams, Robert N, Bethea, Emily, Reynolds, Todd B

“…ScOpi1p is a well-characterized transcriptional repressor and master regulator of inositol and phospholipid biosynthetic genes in the baker's yeast…”
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Studies of Immune Responses in Candida vaginitis by De Bernardis, Flavia, Arancia, Silvia, Sandini, Silvia, Graziani, Sofia, Norelli, Sandro

“…The widespread occurrence of vaginal candidiasis and the development of resistance against anti-fungal agents has stimulated interest in understanding the…”
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Candida albicans Mannoprotein Deprived of Its Mannan Moiety Is Efficiently Taken Up and Processed by Human Dendritic Cells and Induces T-Cell Activation without Stimulating Proinflammatory Cytokine Production by Pietrella, Donatella, Lupo, Patrizia, Rachini, Anna, Sandini, Silvia, Ciervo, Alessandra, Perito, Stefano, Bistoni, Francesco, Vecchiarelli, Anna

“…Mannoproteins are cell wall components of pathogenic fungi and play major virulence and immunogenic roles with both their mannan and protein moieties. The…”
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The 65 kDa mannoprotein gene of Candida albicans encodes a putative ?-glucanase adhesin required for hyphal morphogenesis and experimental pathogenicity by Sandini, Silvia, La Valle, Roberto, De Bernardis, Flavia, Macrì, Caterina, Cassone, Antonio

“…Mannoproteins are fungal cell wall components which play a main role in host-parasite relationship. Camp65p is a putative [beta]-glucanase mannoprotein of 65…”
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A virosomal vaccine against candidal vaginitis: Immunogenicity, efficacy and safety profile in animal models by De Bernardis, Flavia, Amacker, Mario, Arancia, Silvia, Sandini, Silvia, Gremion, Christel, Zurbriggen, Rinaldo, Moser, Christian, Cassone, Antonio

“…Highlights ► We describe the first formulation of a virosomal fungal vaccine. ► Immunogenicity, protection and safety profile are reported for this new…”
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Alternate NF-κB-Independent Signaling Reactivation of Latent HIV-1 Provirus by Acchioni, Chiara, Remoli, Anna Lisa, Marsili, Giulia, Acchioni, Marta, Nardolillo, Ilenia, Orsatti, Roberto, Farcomeni, Stefania, Palermo, Enrico, Perrotti, Edvige, Barreca, Maria Letizia, Sabatini, Stefano, Sandini, Silvia, Parolin, Cristina, Lin, Rongtuan, Borsetti, Alessandra, Hiscott, John, Sgarbanti, Marco

“…Current combination antiretroviral therapies (cART) are unable to eradicate HIV-1 from infected individuals because of the establishment of proviral latency in…”
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A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation by Acchioni, Chiara, Acchioni, Marta, Mancini, Flavia, Amendola, Antonello, Marsili, Giulia, Tirelli, Valentina, Gwee, Chin Piaw, Chan, Kitti Wing-Ki, Sandini, Silvia, Bisbocci, Monica, Mysara, Mohamed, ElHefnawi, Mahmoud, Sanchez, Massimo, Venturi, Giulietta, Barreca, Maria Letizia, Manfroni, Giuseppe, Bresciani, Alberto, Vasudevan, Subhash G., Sgarbanti, Marco

“…Type I interferon (IFN–I) evasion by Dengue virus (DENV) is key in DENV pathogenesis. The non-structural protein 5 (NS5) antagonizes IFN-I response through the…”
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Comparison of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis adhesive properties and pathogenicity by Bertini, Alessia, De Bernardis, Flavia, Hensgens, Lambert A.M., Sandini, Silvia, Senesi, Sonia, Tavanti, Arianna

“…Retrospective studies indicate that Candida metapsilosis and Candida orthopsilosis each represents 1–10% of the infections/colonisations attributed to C…”
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A cell type-specific transcriptomic approach to map B cell and monocyte type I interferon-linked pathogenic signatures in Multiple Sclerosis by Severa, Martina, Rizzo, Fabiana, Srinivasan, Sundararajan, Di Dario, Marco, Giacomini, Elena, Buscarinu, Maria Chiara, Cruciani, Melania, Etna, Marilena P., Sandini, Silvia, Mechelli, Rosella, Farina, Antonella, Trivedi, Pankaj, Hertzog, Paul J., Salvetti, Marco, Farina, Cinthia, Coccia, Eliana M.

“…Alteration in endogenous Interferon (IFN) system may profoundly impact immune cell function in autoimmune diseases. Here, we provide evidence that…”
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Production of a mouse antiserum to Bacteroides fragilis enterotoxin using a recombinant enterotoxin precursor by Sandini, S, Scotto d'Abusco, A, La Valle, R, Pantosti, A

“…The precursor of the Bacteroides fragilis metalloprotease enterotoxin was cloned and expressed in Escherichia coli, which was not able to process the precursor…”
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65 kDa mannoprotein gene of Candida albicans encodes a putative β-glucanase adhesin required for hyphal morphogenesis and experimental pathogenicity by Sandini, Silvia, La Valle, Roberto, De Bernardis, Flavia, Macrì, Caterina, Cassone, Antonio

“…Mannoproteins are fungal cell wall components which play a main role in host-parasite relationship. Camp65p is a putative β-glucanase mannoprotein of 65 kDa…”
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