Search Results - "SANDERSON, David J"

Hippocampal synaptic plasticity, spatial memory and anxiety by Bannerman, David M., Sprengel, Rolf, Sanderson, David J., McHugh, Stephen B., Rawlins, J. Nicholas P., Monyer, Hannah, Seeburg, Peter H.

“…In this Perspective, Seeburg and colleagues re-examine the role of the hippocampus in spatial learning in light of recent findings. They also suggest that the…”
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The role of habituation in hippocampus-dependent spatial working memory tasks: Evidence from GluA1 AMPA receptor subunit knockout mice by Sanderson, David J., Bannerman, David M.

“…Spatial alternation, win‐shift behavior has been claimed to be a test of working memory in rodents that requires active maintenance of relevant, trial‐specific…”
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Systemic inflammation induces acute working memory deficits in the primed brain: relevance for delirium by Murray, Carol, Sanderson, David J, Barkus, Chris, Deacon, Robert M.J, Rawlins, J. Nicholas P, Bannerman, David M, Cunningham, Colm

“…Abstract Delirium is an acute, severe neuropsychiatric syndrome, characterized by cognitive deficits, that is highly prevalent in aging and dementia and is…”
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Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletion by Bannerman, David M, Bus, Thorsten, Taylor, Amy, Sanderson, David J, Schwarz, Inna, Jensen, Vidar, Hvalby, Øivind, Rawlins, J Nicholas P, Seeburg, Peter H, Sprengel, Rolf

“…Using a novel spatial discrimination task, Bannerman and colleagues show that mice lacking hippocampal NMDA receptors in dentate gyrus and CA1 can encode and…”
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Worsening Cognitive Impairment and Neurodegenerative Pathology Progressively Increase Risk for Delirium by Davis, Daniel H.J., M.R.C.P., Ph.D, Skelly, Donal T., Ph.D, Murray, Carol, M.Sc, Hennessy, Edel, B.A, Bowen, Jordan, M.B., B.S, Norton, Samuel, Ph.D, Brayne, Carol, M.D, Rahkonen, Terhi, M.D, Sulkava, Raimo, M.D, Sanderson, David J., Ph.D, Rawlins, J. Nicholas, Ph.D, Bannerman, David M., Ph.D, MacLullich, Alasdair M.J., M.R.C.P., Ph.D, Cunningham, Colm, Ph.D

“…Background Delirium is a profound neuropsychiatric disturbance precipitated by acute illness. Although dementia is the major risk factor this has typically…”
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Contribution of Hippocampal and Extra-Hippocampal NR2B-Containing NMDA Receptors to Performance on Spatial Learning Tasks by von Engelhardt, Jakob, Doganci, Beril, Jensen, Vidar, Hvalby, Øivind, Göngrich, Christina, Taylor, Amy, Barkus, Chris, Sanderson, David J., Rawlins, J. Nicholas P., Seeburg, Peter H., Bannerman, David M., Monyer, Hannah

“…Controversy revolves around the differential contribution of NR2A- and NR2B-containing NMDA receptors, which coexist in principal forebrain neurons, to…”
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Use of Mohr diagrams to predict fracturing in rock masses, with applications for predicting sub-surface behavior by Peacock, D.C.P., Sanderson, David J., Leiss, Bernd

“…Mohr diagrams are a simple and effective method that can help geoscientists consider, model, and predict the ranges of mechanical properties of rock, stresses,…”
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GluA1 AMPAR subunit deletion reduces the hedonic response to sucrose but leaves satiety and conditioned responses intact by Austen, Joseph M., Sprengel, Rolf, Sanderson, David J.

“…The GluA1 subunit of the AMPA receptor has been implicated in schizophrenia. While GluA1 is important for cognition, it is not clear what the role of GluA1 is…”
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Use of Mohr Diagrams to Predict Fracturing in a Potential Geothermal Reservoir by Peacock, D.C.P., Sanderson, David J., Leiss, Bernd

“…Inferences have to be made about likely structures and their effects on fluid flow in a geothermal reservoir at the pre-drilling stage. Simple mechanical…”
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Biomechanical characteristics, patient preference and activity level with different prosthetic feet: A randomized double blind trial with laboratory and community testing by U. Raschke, Silvia, S. Orendurff, Michael, Mattie, Johanne L, Kenyon, David E.A, Jones, O. Yvette, Moe, David, Winder, Lorne, Wong, Angie S, Moreno-Hernández, Ana, Highsmith, M. Jason, J. Sanderson, David, Kobayashi, Toshiki

“…Abstract Providing appropriate prosthetic feet to those with limb loss is a complex and subjective process influenced by professional judgment and payer…”
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Enhanced Long-Term and Impaired Short-Term Spatial Memory in GluA1 AMPA Receptor Subunit Knockout Mice: Evidence for a Dual-Process Memory Model by Sanderson, David J, Good, Mark A, Skelton, Kathryn, Sprengel, Rolf, Seeburg, Peter H, Rawlins, J. Nicholas P, Bannerman, David M

“…The GluA1 AMPA receptor subunit is a key mediator of hippocampal synaptic plasticity and is especially important for a rapidly-induced, short-lasting form of…”
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A bias-free test of human temporal bisection: Evidence against bisection at the arithmetic mean by Sanderson, David J.

“…The temporal bisection procedure has been used to assess theories of time perception. A problem with the procedure for measuring the perceived midpoint of two…”
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Use of Analogue Exposures of Fractured Rock for Enhanced Geothermal Systems by Peacock, D. C. P., Sanderson, David J., Leiss, Bernd

“…Field exposures are often used to provide useful information about sub-surface reservoirs. This paper discusses general lessons learnt about the use of…”
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Altered balance of excitatory and inhibitory learning in a genetically modified mouse model of glutamatergic dysfunction relevant to schizophrenia by Sanderson, David J., Lee, Aletheia, Sprengel, Rolf, Seeburg, Peter H., Harrison, Paul J., Bannerman, David M.

“…The GluA1 AMPAR subunit (encoded by the Gria1 gene) has been implicated in schizophrenia. Gria1 knockout in mice results in recently experienced stimuli…”
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Continual Trials Spontaneous Recognition Tasks in Mice: Reducing Animal Numbers and Improving Our Understanding of the Mechanisms Underlying Memory by Chan, Michele, Eacott, Madeline J, Sanderson, David J, Wang, Jianfei, Sun, Mu, Easton, Alexander

“…Spontaneous recognition tasks are widely used as a laboratory measure of memory in animals but give rise to high levels of behavioral noise leading to a lack…”
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Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder? by Barkus, Chris, Feyder, Michael, Graybeal, Carolyn, Wright, Tara, Wiedholz, Lisa, Izquierdo, Alicia, Kiselycznyk, Carly, Schmitt, Wolfram, Sanderson, David J., Rawlins, J. Nicholas P., Saksida, Lisa M., Bussey, Timothy J., Sprengel, Rolf, Bannerman, David, Holmes, Andrew

“…The glutamate system has been strongly implicated in the pathophysiology of psychotic illnesses, including schizophrenia and schizoaffective disorder. We…”
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Spatial working memory deficits in GluA1 AMPA receptor subunit knockout mice reflect impaired short-term habituation: Evidence for Wagner's dual-process memory model by Sanderson, David J., McHugh, Stephen B., Good, Mark A., Sprengel, Rolf, Seeburg, Peter H., Rawlins, J. Nicholas P., Bannerman, David M.

“…Genetically modified mice, lacking the GluA1 AMPA receptor subunit, are impaired on spatial working memory tasks, but display normal acquisition of spatial…”
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The use of topology in fracture network characterization by Sanderson, David J., Nixon, Casey W.

“…In two-dimensions, a fracture network consist of a system of branches and nodes that can be used to define both geometrical features, such as length and…”
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The influence of seat height on the mechanical function of the triceps surae muscles during steady-rate cycling by Sanderson, David J, Amoroso, Annita T

“…Abstract The purpose of this study was to manipulate bicycle seat height in order to perturbate muscle length, contraction velocity and excitation of soleus…”
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Adaptations to normal human gait on potentially slippery surfaces: The effects of awareness and prior slip experience by Heiden, Tamika L., Sanderson, David J., Inglis, J. Timothy, Siegmund, Gunter P.

“…Prior knowledge of potentially slippery conditions has been shown to alter normal human gait in slip and fall experiments. Here we quantify the effects of two…”
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