Search Results - "SANDERS, Paul W"

Role of Dietary Salt and Potassium Intake in Cardiovascular Health and Disease: A Review of the Evidence by Aaron, Kristal J., BS, MSPH, Sanders, Paul W., MD

“…Abstract The objective of this review was to provide a synthesis of the evidence on the effect of dietary salt and potassium intake on population blood…”
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Mechanisms of Light Chain Injury along the Tubular Nephron by SANDERS, Paul W

“…The tubular nephron is responsible for reabsorption and catabolism of filtered low molecular weight proteins that include Ig free light chains. In the setting…”
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Vascular consequences of dietary salt intake by Sanders, Paul W

“…Animal and human studies support an untoward effect of excess dietary NaCl (salt) intake on cardiovascular and renal function and life span. Recent work has…”
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Novel Paradigms of Salt and Hypertension by Feng, Wenguang, Dell'Italia, Louis J, Sanders, Paul W

“…Salt resistance/sensitivity refers specifically to the effect of dietary sodium chloride (salt) intake on BP. Increased dietary salt intake promotes an early…”
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The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research Group by Leung, Nelson, Bridoux, Frank, Batuman, Vecihi, Chaidos, Aristeidis, Cockwell, Paul, D’Agati, Vivette D., Dispenzieri, Angela, Fervenza, Fernando C., Fermand, Jean-Paul, Gibbs, Simon, Gillmore, Julian D., Herrera, Guillermo A., Jaccard, Arnaud, Jevremovic, Dragan, Kastritis, Efstathios, Kukreti, Vishal, Kyle, Robert A., Lachmann, Helen J., Larsen, Christopher P., Ludwig, Heinz, Markowitz, Glen S., Merlini, Giampaolo, Mollee, Peter, Picken, Maria M., Rajkumar, Vincent S., Royal, Virginie, Sanders, Paul W., Sethi, Sanjeev, Venner, Christopher P., Voorhees, Peter M., Wechalekar, Ashutosh D., Weiss, Brendan M., Nasr, Samih H.

“…The term monoclonal gammopathy of renal significance (MGRS) was introduced by the International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012…”
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KDOQI US Commentary on the 2012 KDIGO Clinical Practice Guideline for Management of Blood Pressure in CKD by Taler, Sandra J., MD, Agarwal, Rajiv, MD, Bakris, George L., MD, Flynn, Joseph T., MD, Nilsson, Peter M., MD, Rahman, Mahboob, MD, Sanders, Paul W., MD, Textor, Stephen C., MD, Weir, Matthew R., MD, Townsend, Raymond R., MD

“…In response to the 2012 KDIGO (Kidney Disease: Improving Global Outcomes) guideline for blood pressure management in patients with chronic kidney disease not…”
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Paraprotein-Related Kidney Disease: Kidney Injury from Paraproteins-What Determines the Site of Injury? by Doshi, Mona, Lahoti, Amit, Danesh, Farhad R, Batuman, Vecihi, Sanders, Paul W

“…Disorders of plasma and B cells leading to paraproteinemias are associated with a variety of renal diseases. Understanding the mechanisms of injury and…”
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Dietary Salt Intake, Salt Sensitivity, and Cardiovascular Health by Sanders, Paul W

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The pathogenesis and diagnosis of acute kidney injury in multiple myeloma by Hutchison, Colin A., Batuman, Vecihi, Behrens, Judith, Bridoux, Frank, Sirac, Christophe, Dispenzieri, Angela, Herrera, Guillermo A., Lachmann, Helen, Sanders, Paul W.

“…Patients with acute kidney injury (AKI) complicating multiple myeloma often have poor outcomes. In this Review, Hutchison et al . discuss the pathogenic role…”
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The Proximal Tubule Toxicity of Immunoglobulin Light Chains by Sirac, Christophe, Batuman, Vecihi, Sanders, Paul W.

“…Plasma and B cells dyscrasias that overproduce monoclonal immunoglobulin free light chains (FLCs) affect the kidney frequently in various ways. The hematologic…”
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Haploinsufficiency of the Transcription Factor Ets-1 Is Renoprotective in Dahl Salt-Sensitive Rats by Feng, Wenguang, Chen, Bo, Xing, Dongqi, Li, Xingsheng, Fatima, Huma, Jaimes, Edgar A, Sanders, Paul W

“…Studies using Dahl salt-sensitive (SS) rats identified specific quantitative trait loci that predispose animals to hypertension-associated albuminuria and…”
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Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1 by Zarjou, Abolfazl, Kim, Junghyun, Traylor, Amie M, Sanders, Paul W, Balla, József, Agarwal, Anupam, Curtis, Lisa M

“…Multipotent mesenchymal stem cells (MSC) have become a popular and promising therapeutic approach in many clinical conditions. MSC are beneficial in animal…”
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Serum free light chain level at diagnosis in myeloma cast nephropathy—a multicentre study by Yadav, Punit, Sathick, Insara Jaffer, Leung, Nelson, Brown, Elizabeth E., Cook, Mark, Sanders, Paul W., Cockwell, Paul

“…Myeloma cast nephropathy (MCN) is a common cause of severe renal impairment in multiple myeloma (MM). The level of free light chain (FLC) that causes MCN…”
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Plasma xanthine oxidase activity is related to increased sodium and left ventricular hypertrophy in resistant hypertension by Butts, Brittany, Calhoun, David A., Denney, Thomas S., Lloyd, Steven G., Gupta, Himanshu, Gaddam, Krishna K., Aban, Inmaculada, Oparil, Suzanne, Sanders, Paul W., Patel, Rakesh, Collawn, James F., Dell’Italia, Louis J.

“…The extra-renal effects of aldosterone on left ventricular (LV) structure and function are exacerbated by increased dietary sodium in persons with…”
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Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model by Ying, Wei-Zhong, Allen, Christopher E, Curtis, Lisa M, Aaron, Kristal J, Sanders, Paul W

“…A common renal complication of multiple myeloma is "myeloma kidney," a condition also known as cast nephropathy. The renal lesions (casts) are directly related…”
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Community Mobility Among Older Adults With Reduced Kidney Function: A Study of Life-Space by Bowling, C. Barrett, MD, MSPH, Muntner, Paul, PhD, Sawyer, Patricia, PhD, Sanders, Paul W., MD, Kutner, Nancy, PhD, Kennedy, Richard, MD, PhD, Allman, Richard M., MD

“…Background Life-Space Assessment captures community mobility and social participation and quantifies the distance, frequency, and independence obtained as an…”
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Sodium and potassium excretion predict increased depression in urban adolescents by Mrug, Sylvie, Orihuela, Catheryn, Mrug, Michal, Sanders, Paul W.

“…This study examined the prospective role of urinary sodium and potassium excretion in depressive symptoms among urban, low‐income adolescents, and whether…”
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Renin-Angiotensin Inhibition in Systolic Heart Failure and Chronic Kidney Disease by Ahmed, Ali, MD, Fonarow, Gregg C., MD, Zhang, Yan, MS, MSPH, Sanders, Paul W., MD, Allman, Richard M., MD, Arnett, Donna K., PhD, Feller, Margaret A., MPH, Love, Thomas E., PhD, Aban, Inmaculada B., PhD, Levesque, Raynald, MS, Ekundayo, O. James, MD, DrPH, Dell'Italia, Louis J., MD, Bakris, George L., MD, Rich, Michael W., MD

“…Abstract Background The role of renin-angiotensin inhibition in older patients with systolic heart failure with chronic kidney disease remains unclear. Methods…”
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Chronic Kidney Disease Associated Mortality in Diastolic Versus Systolic Heart Failure: A Propensity Matched Study by Ahmed, Ali, MD, MPH, Rich, Michael W., MD, Sanders, Paul W., MD, Perry, Gilbert J., MD, Bakris, George L., MD, Zile, Michael R., MD, Love, Thomas E., PhD, Aban, Inmaculada B., PhD, Shlipak, Michael G., MD, MPH

“…Chronic kidney disease (CKD) is common and is associated with increased mortality in heart failure (HF). However, it is unknown whether the effect of CKD on…”
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Dietary salt initiates redox signaling between endothelium and vascular smooth muscle through NADPH oxidase 4 by Ying, Kai er, Feng, Wenguang, Ying, Wei-Zhong, Li, Xingsheng, Xing, Dongqi, Sun, Yong, Chen, Yabing, Sanders, Paul W.

“…Prevention of phenotype switching of vascular smooth muscle cells is an important determinant of normal vascular physiology. Hydrogen peroxide (H2O2) promotes…”
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