Search Results - "SANDERS, P. E."

Pharmacokinetics, Metabolism, and Excretion of Linezolid following an Oral Dose of [14C]Linezolid to Healthy Human Subjects by SLATTER, J. G, STALKER, D. J, STRYD, R. P, PENG, G. W, SHOBE, E. M, FEENSTRA, K. L, WELSHMAN, I. R, BRUSS, J. B, SAMS, J. P, JOHNSON, M. G, SANDERS, P. E, HAUER, M. J, FAGERNESS, P. E

“…Linezolid (Zyvox), the first of a new class of antibiotics, the oxazolidinones, is approved for treatment of Gram-positive bacterial infections, including…”
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Metabolism of Delavirdine, a Human Immunodeficiency Virus Type-1 Reverse Transcriptase Inhibitor, by Microsomal Cytochrome P450 in Humans, Rats, and Other Species: Probable Involvement of CYP2D6 and CYP3A by VOORMAN, R. L, MAIO, S. M, HAUER, M. J, SANDERS, P. E, PAYNE, N. A, ACKLAND, M. J

“…The metabolism of delavirdine was examined using liver microsomes from several species with the aim of comparing metabolite formation among species and…”
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Covenantal Nomism Revisited by Sanders, E. P.

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Biotransformation of tirilazad in human: 1. Cytochrome P450 3A-mediated hydroxylation of tirilazad mesylate in human liver microsomes by Wienkers, L C, Steenwyk, R C, Sanders, P E, Pearson, P G

“…Tirilazad mesylate (Freedox), a potent inhibitor of membrane lipid peroxidation in vitro, is under clinical development for the treatment of subarachnoid…”
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Metabolism of the bisphosphonate ester U-91502 in rats by Slatter, J G, Feenstra, K L, Hauer, M J, Kloosterman, D A, Parton, A H, Sanders, P E, Scott, G, Speed, W

“…The major metabolites of the bisphosphonate ester U-91502 were isolated from the bile and urine of male Sprague-Dawley rats and identified by NMR and MS. Bile…”
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Biotransformation of lifibrol (U-83860) to mixed glyceride metabolites by rat and human hepatocytes in primary culture by Sun, E L, Feenstra, K L, Bell, F P, Sanders, P E, Slatter, J G, Ulrich, R G

“…Lifibrol (U-83860), K12.148) is a lipid-lowering drug that has the potential to accumulate in the liver and induce hepatic peroxisome proliferation. To…”
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In vitro and in vivo biotransformation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-D]pyrimidine (U-89843) in the rat by Zhao, Z, Koeplinger, K A, Bundy, G L, Banitt, L S, Padbury, G E, Hauer, M J, Sanders, P E

“…The biotransformation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) has been studied in rat both in vitro and in vivo. Major…”
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In vitro metabolic transformations of 2,4-dipyrrolidinylpyrimidine: a chemical probe for P450-mediated oxidation of tirilazad mesylate by STREEPER, R. T, PEARSON, P. G, ZHAO, Z, MIZSAK, S. A, SANDERS, P. E, WIENKERS, L. C, VRBANAC, J. J

“…1. We have determined that 2,4-dipyrrolidinylpyrimidine (2,4-DPP), used as a model for studies of the metabolism of therapeutic agents containing this moiety,…”
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Preparation and characterization of the deepoxy trichothecenes: deepoxy HT-2, deepoxy T-2 triol, deepoxy T-2 tetraol, deepoxy 15-monoacetoxyscirpenol, and deepoxy scirpentriol by SWANSON, S. P, ROOD, H. D. JR, BEHRENS, J. C, SANDERS, P. E

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Metabolism of the human immunodeficiency virus type 1 reverse transcriptase inhibitor delavirdine in rats by CHANG, M, SOOD, V. K, WILSON, G. J, KLOOSTERMAN, D. A, SANDERS, P. E, HAUER, M. J, FAGERNESS, P. E

“…Delavirdine mesylate (U-90152T) is a highly specific nonnucleoside reverse transcriptase inhibitor currently under development for the treatment of AIDS. The…”
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Metabolism of a bisphosphonate ester (PNU-91638) in rat by SLATTER, J. G., FEENSTRA, K. L., HAUER, M. J., SANDERS, P. E., VRBANAC, J. J., SCOTT, G., SPEED, W.

“…1. Metabolites of the cyclic bisphosphonate ester, 4-[2,2′-bis-(5,5-dimethyl-1,3,2-dioxaphosphorinan-2-yl)] butanoyl-3-fluoro-benzene (PNU-91638) in bile or…”
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Metabolism of the HIV-1 Reverse Transcriptase Inhibitor Delavirdine In Mice by CHANG, M, SOOD, V. K, WILSON, G. J, KLOOSTERMAN, D. A, SANDERS, P. E, HAUER, M. J, ZHANG, W, BRANSTETTER, D. G

“…Delavirdine mesylate (U-90152T) is a highly specific nonnucleoside HIV-1 reverse transcriptase inhibitor currently under development for the treatment of AIDS…”
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Identification of the Metabolites of the HIV-1 Reverse Transcriptase Inhibitor Delavirdine in Monkeys by CHANG, M, SOOD, V. K, KLOOSTERMAN, D. A, HAUER, M. J, FAGERNESS, P. E, SANDERS, P. E, VRBANAC, J. J

“…Delavirdine mesylate (U-90152T) is a highly specific nonnucleoside HIV-1 reverse transcriptase inhibitor currently under development for the treatment of AIDS…”
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Absorption, Distribution, Metabolism, and Excretion of Atevirdine in the Rat by CHANG, M, SOOD, V. K, WILSON, G. J, KLOOSTERMAN, D. A, SANDERS, P. E, SCHUETTE, M. R, JUDY, R. W, VOORMAN, R. L, MAIO, S. M, SLATTER, J. G

“…Atevirdine mesylate (U-87201E) is a highly specific nonnucleoside inhibitor of human immunodeficiency virus type 1 reverse transcriptase. The absorption,…”
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Polychlorinated biphenyl contamination of domestic turkeys from building materials by Hansen, Larry G, Sullivan, J. M, Neff, C. C, Sanders, P. E, Lambert, R. J, Beasley, V. R, Storr-Hansen, E

“…The source of polychorinated biphenyl contamination in commercially reared turkeys was determined in a field study. Samples of turkey tissue and building…”
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Interaction of Delavirdine with Human Liver Microsomal Cytochrome P450: Inhibition of CYP2C9, CYP2C19, and CYP2D6 by VOORMAN, Richard L, PAYNE, N. Ann, WIENKERS, Larry C, HAUER, Michael J, SANDERS, Phillip E

“…Delavirdine, a non-nucleoside inhibitor of HIV-1 reverse transcriptase, is metabolized primarily through desalkylation catalyzed by CYP3A4 and CYP2D6 and by…”
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Patterns of Religion in Paul and Rabbinic Judaism: A Holistic Method of Comparison by Sanders, E. P.

“…There have been two principal ways of comparing Paul with Judaism, each of which has suffered from characteristic defects. One has been holistic in a certain…”
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Quantitative analysis quantitation of 2- n-nonyl-1,3-dioxolane by stable-isotope dilution gas chromatography-mass spectrometry by Zhong, W.Z, Sanders, P.E, Hauer, M.J, Vrbanac, J.J

“…We report here a quantitative methodology developed for determination of SEPA (2- n-nonyl-1,3-dioxolane) in human serum. The method employed solid-phase…”
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Jerusalem and its temple in the beginnings of the Christian Movement by Sanders, E.P

“…Sanders considers what Paul and Jesus thought of Jerusalem at the beginning of the Christian movement. Jesus held fairly conservative views about Jerusalem and…”
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Mediating Influences of Negative Affect and Risk Perception on the Relationship Between Sensation Seeking and Adolescent Cigarette Smoking by Doran, Neal, Sanders, Patricia E., Bekman, Nicole M., Worley, Matthew J., Monreal, Teresa K., McGee, Elizabeth, Cummins, Kevin, Brown, Sandra A.

“…A substantial number of adolescents are current and regular cigarette smokers, and there is a need to better understand factors that contribute to smoking…”
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