Search Results - "SANDERS, J. Michael"

Disposition of the Emerging Brominated Flame Retardant, 2-Ethylhexyl 2,3,4,5-Tetrabromobenzoate, in Female SD Rats and Male B6C3F1 Mice: Effects of Dose, Route, and Repeated Administration by Knudsen, Gabriel A, Sanders, J Michael, Birnbaum, Linda S

“…2-Ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB; MW 549.92 g/mol; CAS 183658-27-7) is a brominated component of flame retardant mixtures used as substitutes…”
Get full text

Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats by Dunnick, June K., Shockley, Keith R., Morgan, Daniel L., Brix, Amy, Travlos, Gregory S., Gerrish, Kevin, Michael Sanders, J., Ton, T. V., Pandiri, Arun R.

“…N , N -dimethyl- p -toluidine (DMPT), an accelerant for methyl methacrylate monomers in medical devices, was a liver carcinogen in male and female F344/N rats…”
Get full text

Investigating the Potential for Toxicity from Long-Term Use of the Herbal Products, Goldenseal and Milk Thistle by Dunnick, June K., Singh, Bhanu, Nyska, Abraham, Peckham, John, Kissling, Grace E., Sanders, J. Michael

“…Two-year toxicity studies were conducted on the widely used herbal products, goldenseal and milk thistle, in male and female F344/N rats and B6C3F1 mice. With…”
Get full text

Disposition and metabolism of 2′,2′”-Dithiobisbenzanilide in rodents following intravenous and oral administration and dermal application by Garner, C. Edwin, Wegerski, Christopher J., Doyle-Eisele, Melanie, McDonald, Jacob D., Sanders, J. Michael, Moeller, Benjamin C., Waidyanatha, Suramya

“…•2′,2′′′-Dithiobisbenzanilide (DTBBA) is a chemical used as a peptizing agent for rubber.•Humane exposure to DTBBA is possible via oral and dermal…”
Get full text

Shearing Behavior of Tire-Derived Aggregate with Large Particle Size. I: Internal and Concrete Interface Direct Shear by Ghaaowd, Ismaail, McCartney, John S, Thielmann, Stuart S, Sanders, Michael J, Fox, Patrick J

“…AbstractTire-derived aggregate (TDA) has been used widely in civil engineering applications such as highway embankments, light rail foundations, landslide…”
Get full text

METTĀNOIA IN THOMAS PYNCHON’S BUDDHIST TRILOGY by Sanders, Michael J.

“…This article argues for the centrality of Buddhism in Thomas Pynchon’s fiction. The Crying of Lot 49, Vineland, and Bleeding Edge make a Buddhist Trilogy. As…”
Get full text

Disposition of the emerging brominated flame retardant, bis(2-ethylhexyl) tetrabromophthalate, in female Sprague Dawley rats: effects of dose, route and repeated administration by Knudsen, Gabriel A., Sanders, J. Michael, Birnbaum, Linda S.

“…1. Bis(2-ethylhexyl)-tetrabromophthalate (BEH-TEBP; CAS No. 26040-51-7; PubChem CID: 117291; MW 706.15 g/mol, elsewhere: TeBrDEPH, TBPH, or BEHTBP) is used as…”
Get full text

Shearing Behavior of Tire-Derived Aggregate with Large Particle Size. II: Cyclic Simple Shear by McCartney, John S, Ghaaowd, Ismaail, Fox, Patrick J, Sanders, Michael J, Thielmann, Stuart S, Sander, Andrew C

“…AbstractAlthough tire-derived aggregate (TDA) has been used widely as lightweight fill in civil engineering applications, the properties governing its response…”
Get full text

Absorption, Distribution, Metabolism, and Excretion of 2,2-Bis(bromomethyl)-1,3-propanediol in Male Fischer-344 Rats by HOEHLE, Simone I, KNUDSEN, Gabriel A, SANDERS, J. Michael, SIPES, I. Glenn

“…2,2-Bis(bromomethyl)-1,3-propanediol (BMP) is a brominated flame retardant, previously shown to be a multisite carcinogen in experimental animals. Studies were…”
Get full text

Disruption of estrogen homeostasis as a mechanism for uterine toxicity in Wistar Han rats treated with tetrabromobisphenol A by Sanders, J. Michael, Coulter, Sherry J., Knudsen, Gabriel A., Dunnick, June K., Kissling, Grace E., Birnbaum, Linda S.

“…Chronic oral treatment of tetrabromobisphenol A (TBBPA) to female Wistar Han rats resulted in increased incidence of cell proliferation at 250mg/kg and tumor…”
Get full text

Disposition of β-N-methylamino-l-alanine (L-BMAA), a neurotoxin, in rodents following a single or repeated oral exposure by Waidyanatha, Suramya, Ryan, Kristen, Sanders, J. Michael, McDonald, Jacob D., Wegerski, Christopher J., Doyle-Eisle, Melanie, Garner, C. Edwin

“…β-N-methylamino-l-alanine (L-BMAA) is produced by cyanobacteria (blue-green algae). Human exposure to L-BMAA occurs via consumption of L-BMAA-contaminated…”
Get full text

Estimation of human percutaneous bioavailability for two novel brominated flame retardants, 2-ethylhexyl 2,3,4,5-tetrabromobenzoate (EH-TBB) and bis(2-ethylhexyl) tetrabromophthalate (BEH-TEBP) by Knudsen, Gabriel A., Hughes, Michael F., Sanders, J. Michael, Hall, Samantha M., Birnbaum, Linda S.

“…2-Ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB) and bis(2-ethylhexyl)tetrabromophthalate (BEH-TEBP) are novel brominated flame retardants used in consumer…”
Get full text

Estimation of tetrabromobisphenol A (TBBPA) percutaneous uptake in humans using the parallelogram method by Knudsen, Gabriel A., Hughes, Michael F., McIntosh, Katelyn L., Sanders, J. Michael, Birnbaum, Linda S.

“…Tetrabromobisphenol A (TBBPA) is currently the world's highest production volume brominated flame retardant. Humans are frequently exposed to TBBPA by the…”
Get full text

Gene expression changes in immune response pathways following oral administration of tetrabromobisphenol A (TBBPA) in female Wistar Han rats by Hall, Samantha M., Coulter, Sherry J., Knudsen, Gabriel A., Sanders, J. Michael, Birnbaum, Linda S.

“…•Perturbation of biological pathways in TBBPA-exposed female rats was studied.•Gene expression changes were observed with microarray and validated with…”
Get full text

Disposition and metabolism of 2,2′-dimorpholinodiethyl ether in sprague dawley rats and B6C3F1/N mice after oral, intravenous administration, and dermal application by Waidyanatha, Suramya, McDonald, Jacob D., Sanders, J. Michael, Doyle-Eisele, Melanie, Moeller, Benjamin C., Garner, C. Edwin

“…The specialty amine catalyst 2,2′-dimorpholinodiethyl ether (DMDEE) is a high-production volume chemical used in the production of flexible foam,…”
Get full text

The fate of β-hexabromocyclododecane in female C57BL/6 mice by Sanders, J Michael, Knudsen, Gabriel A, Birnbaum, Linda S

“…1,2,5,6,9,10-Hexabromocyclododecane (HBCD) is a high production volume cycloaliphatic used as an additive flame retardant primarily in polystyrene foam…”
Get full text

The biological fate of decabromodiphenyl ethane following oral, dermal or intravenous administration by Knudsen, Gabriel A., Sanders, J. Michael, Hughes, Michael F., Hull, Ethan P., Birnbaum, Linda S.

“…1. It was important to investigate the disposition of decabromodiphenyl ethane (DBDPE) based on concerns over its structural similarities to decabromodiphenyl…”
Get full text

Disposition and kinetics of tetrabromobisphenol A in female Wistar Han rats by Knudsen, Gabriel A., Sanders, J. Michael, Sadik, Abdella M., Birnbaum, Linda S.

“…Tetrabromobisphenol A (TBBPA) is the brominated flame retardant with the largest production volume worldwide. NTP 2-year bioassays found TBBPA dose-dependent…”
Get full text

Proposed mechanistic description of dose-dependent BDE-47 urinary elimination in mice using a physiologically based pharmacokinetic model by Emond, Claude, Sanders, J. Michael, Wikoff, Daniele, Birnbaum, Linda S.

“…Polybrominated diphenyl ethers (PBDEs) have been used in a wide variety of consumer applications as additive flame retardants. In North America, scientists…”
Get full text

Toxicology and Carcinogenesis Study of Senna in C3B6.129F1-Trp53 tm1Brd N12 Haploinsufficient Mice by Surh, Inok, Brix, Amy, French, John E., Collins, Bradley J., Sanders, J. Michael, Vallant, Molly, Dunnick, June K.

“…Senna is a pod or leaf of Senna alexandrina P. Mill and is used as a stimulant laxative. In the large intestine, bacterial enzymes reduce sennosides to…”
Get full text