Search Results - "SANDANAYAKE, Neomal"

Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection by O'Brien, Darragh P, Sandanayake, Neomal S, Jenkinson, Claire, Gentry-Maharaj, Aleksandra, Apostolidou, Sophia, Fourkala, Evangelia-Ourania, Camuzeaux, Stephane, Blyuss, Oleg, Gunu, Richard, Dawnay, Anne, Zaikin, Alexey, Smith, Ross C, Jacobs, Ian J, Menon, Usha, Costello, Eithne, Pereira, Stephen P, Timms, John F

“…Biomarkers for the early detection of pancreatic cancer are urgently needed. The primary objective of this study was to evaluate whether increased levels of…”
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Presentation and Management of Post-treatment Relapse in Autoimmune Pancreatitis/Immunoglobulin G4-Associated Cholangitis by Sandanayake, Neomal S, Church, Nicholas I, Chapman, Michael H, Johnson, Gavin J, Dhar, Dipok K, Amin, Zahir, Deheragoda, Maesha G, Novelli, Marco, Winstanley, Alison, Rodriguez–Justo, Manuel, Hatfield, Adrian R.W, Pereira, Stephen P, Webster, George J.M

“…Background & Aims Autoimmune pancreatitis (AIP) is a multisystem disorder that often has extrapancreatic manifestations such as immunoglobulin G4–associated…”
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Calcineurin inhibitors in steroid and anti‐TNF‐alpha refractory immune checkpoint inhibitor colitis by Zhang, Eva, Kiely, Christopher, Sandanayake, Neomal, Tattersall, Stephen

“…Background and Aim Immune checkpoint inhibitor (ICI) colitis is an increasingly common problem encountered as the use of checkpoint inhibitors (CPIs) grows in…”
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Clinicopathological characteristics and management of colitis with anti-PD1 immunotherapy alone or in combination with ipilimumab by Nahar, Kazi J, Rawson, Robert V, Ahmed, Tasnia, Tattersall, Stephen, Sandanayake, Neomal, Kiely, Christopher J, Lo, Serigne, Carlino, Matteo, Palendira, Umaimainthan, Scolyer, Richard A, Long, Georgina V, Menzies, Alexander M

“…BackgroundColitis is one of the common immune-related adverse events that leads to morbidity and treatment discontinuation of immunotherapy. The clinical…”
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Autoimmune Pancreatitis: Clinical and Radiological Features and Objective Response to Steroid Therapy in a UK Series by CHURCH, Nicholas I, PEREIRA, Stephen P, HATFIELD, Adrian R. W, WEBSTER, George J. M, DEHERAGODA, Maesha G, SANDANAYAKE, Neomal, AMIN, Zahir, LEES, William R, GILLAMS, Alice, RODRIGUEZ-JUSTO, Manuel, NOVELLI, Marco, SEWARD, Edward W

“…Most cases of autoimmune pancreatitis (AIP) have been reported from Japan. We present data on a UK series, including clinical and radiological features at…”
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Pyruvate kinase M2 is a novel diagnostic marker and predicts tumor progression in human biliary tract cancer by Dhar, Dipok Kumar, Olde Damink, Steven W.M., Brindley, James Hal, Godfrey, Andrew, Chapman, Michael H., Sandanayake, Neomal S., Andreola, Fausto, Mazurek, Sybille, Hasan, Tayyaba, Malago, Massimo, Pereira, Stephen P.

“…BACKGROUND: The early diagnosis of biliary tract cancer (BTC) remains challenging, and there are few effective therapies. This study investigated whether the…”
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Endoscopic Retrograde Cholangiography Does Not Reliably Distinguish IgG4-Associated Cholangitis From Primary Sclerosing Cholangitis or Cholangiocarcinoma by Kalaitzakis, Evangelos, Levy, Michael, Kamisawa, Terumi, Johnson, Gavin J, Baron, Todd H, Topazian, Mark D, Takahashi, Naoki, Kanno, Atsushi, Okazaki, Kazuichi, Egawa, Naoto, Uchida, Kazushige, Sheikh, Kashif, Amin, Zahir, Shimosegawa, Tooru, Sandanayake, Neomal S, Church, Nicholas I, Chapman, Michael H, Pereira, Stephen P, Chari, Suresh, Webster, George J.M

“…Background & Aims Distinction of immunoglobulin G4–associated cholangitis (IAC) from primary sclerosing cholangitis (PSC) or cholangiocarcinoma is challenging…”
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Whole genome RNA expression profiling of endoscopic biliary brushings provides data suitable for biomarker discovery in cholangiocarcinoma by Chapman, Michael H, Tidswell, Robert, Dooley, James S, Sandanayake, Neomal S, Cerec, Virginie, Deheragoda, Maesha, Lee, Alvin J.X, Swanton, Charles, Andreola, Fausto, Pereira, Stephen P

“…Background & Aims Molecular analyses of biliary brushings using microarray and qPCR have the potential to provide valuable information on the biology of…”
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Life-threatening diarrhea in neuroendocrine tumors: two case reports by Gordon, Emma, Chan, David L, Arena, Jennifer, Bernard, Elizabeth, Carr-Boyd, Emily, Clarke, Stephen J, Itchins, Malinda, Learoyd, Diana, Sandanayake, Neomal, Pavlakis, Nick

“…Abstract Background Neuroendocrine tumors are rare, heterogeneous neoplasms that produce a wide variety of clinical symptoms. Diarrhea in neuroendocrine tumors…”
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Mo1877 Infliximab for the Treatment of Ipilimumab (anti CTLA-4) and Nivolumab/Pembrolizumab (anti-PD-1) Associated Colitis by Sidhu, Mayenaaz, Mersaides, Antony, Liniker, Elizabeth, Tate, David J, Nagrial, Adnan, Long, Georgina, Sandanayake, Neomal S, Kariyawasam, Viraj C, Carlino, Matteo S, Kwan, Vu

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The Use of Immunoglobulin G4 Immunostaining in Diagnosing Pancreatic and Extrapancreatic Involvement in Autoimmune Pancreatitis by Deheragoda, Maesha G, Church, Nicholas I, Rodriguez–Justo, Manuel, Munson, Philippa, Sandanayake, Neomal, Seward, Edward W, Miller, Keith, Novelli, Marco, Hatfield, Adrian R.W, Pereira, Stephen P, Webster, George J.M

“…Background & Aims: Autoimmune pancreatitis (AIP) is recognized increasingly as a multisystem disorder. We evaluated the use of immunoglobulin (Ig)G4…”
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Circulating CYFRA 21-1 is a Specific Diagnostic and Prognostic Biomarker in Biliary Tract Cancer by Chapman, Michael H, PhD MRCP, Sandanayake, Neomal S, FRACP, Andreola, Fausto, PhD, Dhar, Dipok K, MBBS, Webster, George J, MD FRCP, Dooley, James S, MD FRCP, Pereira, Stephen P, PhD FRCP

“…Abstract Background Biliary tract cancer (BTC) has a poor prognosis, in part related to difficulties in diagnosis. Cytokeratin 19 (CK19) is a constituent of…”
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Distinct pretreatment innate immune landscape and posttreatment T cell responses underlie immunotherapy-induced colitis by Nahar, Kazi J, Marsh-Wakefield, Felix, Rawson, Robert V, Gide, Tuba N, Ferguson, Angela L, Allen, Ruth, Quek, Camelia, da Silva, Ines Pires, Tattersal, Stephen, Kiely, Christopher J, Sandanayake, Neomal, Carlino, Matteo S, McCaughan, Geoff, Wilmott, James S, Scolyer, Richard A, Long, Georgina V, Menzies, Alexander M, Palendira, Umaimainthan

“…Immune-related adverse events represent a major hurdle to the success of immunotherapy. The immunological mechanisms underlying their development and relation…”
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Identification of potential serum peptide biomarkers of biliary tract cancer using MALDI MS profiling by Sandanayake, Neomal S, Camuzeaux, Stephane, Sinclair, John, Blyuss, Oleg, Andreola, Fausto, Chapman, Michael H, Webster, George J, Smith, Ross C, Timms, John F, Pereira, Stephen P

“…The aim of this discovery study was the identification of peptide serum biomarkers for detecting biliary tract cancer (BTC) using samples from healthy…”
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R0 but not R1/R2 resection is associated with better survival than palliative photodynamic therapy in biliary tract cancer by Matull, Wolf-Rudiger, Dhar, Dipok K., Ayaru, Lakshmana, Sandanayake, Neomal S., Chapman, Michael H., Dias, Aruna, Bridgewater, John, Webster, George J. M., Bong, Jin J., Davidson, Brian R., Pereira, Stephen P.

“…Background: There is a need for better management strategies to improve the survival and quality of life in patients with biliary tract cancer (BTC). Aim: To…”
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T1394 Serum CEACAM1 in the Preclinical Diagnosis of Pancreatic Adenocarcinoma by Sandanayake, Neomal S, Andreola, Fausto, Camuzeaux, Stephane, Sinclair, John, Chapman, Michael H, Webster, George, Gentry-Maharaj, Aleksandra, Menon, Usha, Jacobs, Ian, Pereira, Stephen P, Timms, John F

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S1890 Characterisation of Serum Proteins in Biliary Tract Cancer, PSC and Iac Using 2-Dimensional Difference Gel Electrophoresis and Tandem Mass Spectrometry by Sandanayake, Neomal S, Sinclair, John, Andreola, Fausto, Chapman, Michael H, Camuzeaux, Stephane, Webster, George, Norton, Ian D, Smith, Ross, Timms, John F, Pereira, Stephen P

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M1384 Longterm Outcome in Autoimmune Pancreatitis - Do Steroids Preserve Pancreatic Structure and Function? by Sandanayake, Neomal S, Chapman, Michael H, Kalaitzakis, Evangelos, Amin, Zahir, Novelli, Marco, Winstanley, Alison, Rodriguez-Justo, Manuel, Hatfield, Adrian R, Pereira, Stephen P, Webster, George

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S1891 Biliary Tract Cancer Serum Profiling Using Magnetic C18 Bead-Based Peptide Extraction and MALDI-TOF Mass Spectrometry by Sandanayake, Neomal S, Camuzeaux, Stephane, Sinclair, John, Chapman, Michael H, Bell, Cameron J, Norton, Ian D, Webster, George, Smith, Ross, Timms, John F, Pereira, Stephen P

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72 Azathioprine in the Management of Relapsing Autoimmune Pancreatitis/IgG4 Sclerosing Cholangitis by Sandanayake, Neomal S, Hatfield, Adrian R, Pereira, Stephen P, Webster, George J

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