Search Results - "SAMUEL, Melanie A"

Microglia in the developing retina by Li, Fenge, Jiang, Danye, Samuel, Melanie A

“…Microglia are increasingly shown to be key players in neuron development and synapse connectivity. However, the underlying mechanisms by which microglia…”
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Age-related alterations in neurons of the mouse retina by Samuel, Melanie A, Zhang, Yifeng, Meister, Markus, Sanes, Joshua R

“…The behavioral consequences of age-related alterations in neural function are well documented, but less is known about their cellular bases. To characterize…”
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Pathogenesis of west nile virus infection : a balance between virulence, innate and adaptive immunity, and viral evasion by SAMUEL, Melanie A, DIAMOND, Michael S

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Toll-Like Receptor 3 Has a Protective Role against West Nile Virus Infection by DAFFIS, Stephane, SAMUEL, Melanie A, SUTHAR, Mehul S, GALE, Michael, DIAMOND, Michael S

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Agrin and synaptic laminin are required to maintain adult neuromuscular junctions by Samuel, Melanie A, Valdez, Gregorio, Tapia, Juan C, Lichtman, Jeff W, Sanes, Joshua R

“…As synapses form and mature the synaptic partners produce organizing molecules that regulate each other's differentiation and ensure precise apposition of pre-…”
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Alpha/Beta Interferon Protects against Lethal West Nile Virus Infection by Restricting Cellular Tropism and Enhancing Neuronal Survival by SAMUEL, Melanie A, DIAMOND, Michael S

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Post-developmental plasticity of the primary rod pathway allows restoration of visually guided behaviors by Cao, Yan, Fajardo, Diego, Guerrero-Given, Debbie, Samuel, Melanie A, Ohtsuka, Toshihisa, Boye, Shannon E, Kamasawa, Naomi, Martemyanov, Kirill A

“…The formation of neural circuits occurs in a programmed fashion, but proper activity in the circuit is essential for refining the organization necessary for…”
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LKB1 and AMPK regulate synaptic remodeling in old age by Samuel, Melanie A, Voinescu, P Emanuela, Lilley, Brendan N, de Cabo, Rafa, Foretz, Marc, Viollet, Benoit, Pawlyk, Basil, Sandberg, Michael A, Vavvas, Demetrios G, Sanes, Joshua R

“…In this study, the authors show that age-related aberrant synaptic remodeling in the retinal outer plexiform layer is mediated by LBK1-AMPK signaling. They…”
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The Immune Adaptor Molecule SARM Modulates Tumor Necrosis Factor Alpha Production and Microglia Activation in the Brainstem and Restricts West Nile Virus Pathogenesis by SZRETTER, Kristy J, SAMUEL, Melanie A, GILFILLAN, Susan, FUCHS, Anja, COLONNA, Marco, DIAMOND, Michael S

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Axonal transport mediates West Nile virus entry into the central nervous system and induces acute flaccid paralysis by Samuel, Melanie A, Wang, Hong, Siddharthan, Venkatraman, Morrey, John D, Diamond, Michael S

“…West Nile virus (WNV) has emerged as a significant cause of epidemic viral encephalitis and flaccid limb paralysis, yet the mechanism by which it enters the…”
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Caspase 3-Dependent Cell Death of Neurons Contributes to the Pathogenesis of West Nile Virus Encephalitis by SAMUEL, Melanie A, MORREY, John D, DIAMOND, Michael S

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C1q Regulates Horizontal Cell Neurite Confinement in the Outer Retina by Burger, Courtney A., Jiang, Danye, Li, Fenge, Samuel, Melanie A.

“…During development, neurons generate excess processes which are then eliminated in concert with circuit maturation. C1q is the initiating protein in the…”
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Progressive myoclonic epilepsy-associated gene Kctd7 regulates retinal neurovascular patterning and function by Alevy, Jonathan, Burger, Courtney A., Albrecht, Nicholas E., Jiang, Danye, Samuel, Melanie A.

“…Neuron function relies on and instructs the development and precise organization of neurovascular units that in turn support circuit activity. However, our…”
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Six RNA viruses and forty-one hosts: viral small RNAs and modulation of small RNA repertoires in vertebrate and invertebrate systems by Parameswaran, Poornima, Sklan, Ella, Wilkins, Courtney, Burgon, Trever, Samuel, Melanie A, Lu, Rui, Ansel, K Mark, Heissmeyer, Vigo, Einav, Shirit, Jackson, William, Doukas, Tammy, Paranjape, Suman, Polacek, Charlotta, dos Santos, Flavia Barreto, Jalili, Roxana, Babrzadeh, Farbod, Gharizadeh, Baback, Grimm, Dirk, Kay, Mark, Koike, Satoshi, Sarnow, Peter, Ronaghi, Mostafa, Ding, Shou-Wei, Harris, Eva, Chow, Marie, Diamond, Michael S, Kirkegaard, Karla, Glenn, Jeffrey S, Fire, Andrew Z

“…We have used multiplexed high-throughput sequencing to characterize changes in small RNA populations that occur during viral infection in animal cells. Small…”
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Neuronal CXCL10 Directs CD8+ T-Cell Recruitment and Control of West Nile Virus Encephalitis by KLEIN, Robyn S, LIN, Eugene, BO ZHANG, LUSTER, Andrew D, TOLLETT, Judy, SAMUEL, Melanie A, ENGLE, Michael, DIAMOND, Michael S

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Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects by Liang, Justine H, Alevy, Jonathan, Akhanov, Viktor, Seo, Ryan, Massey, Cory A, Jiang, Danye, Zhou, Joy, Sillitoe, Roy V, Noebels, Jeffrey L, Samuel, Melanie A

“…Mutations in the potassium channel tetramerization domain-containing 7 (KCTD7) gene are associated with a severe neurodegenerative phenotype characterized by…”
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Gamma Interferon Plays a Crucial Early Antiviral Role in Protection against West Nile Virus Infection by SHRESTHA, Bimmi, TIAN WANG, SAMUEL, Melanie A, WHITBY, Kevin, CRAFT, Joe, FIKRIG, Erol, DIAMOND, Michael S

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Interferon Regulatory Factor IRF-7 Induces the Antiviral Alpha Interferon Response and Protects against Lethal West Nile Virus Infection by DAFFIS, Stephane, SAMUEL, Melanie A, SUTHAR, Mehul S, KELLER, Brian C, GALE, Michael, DIAMOND, Michael S

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CD8+ T Cells Require Perforin To Clear West Nile Virus from Infected Neurons by SHRESTHA, Bimmi, SAMUEL, Melanie A, DIAMOND, Michael S

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Differential Replication of Pathogenic and Nonpathogenic Strains of West Nile Virus within Astrocytes by Hussmann, Katherine L, Samuel, Melanie A, Kim, Kwang S, Diamond, Michael S, Fredericksen, Brenda L

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