Search Results - "SAMPATH, K"

Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling by Loganathan, Sampath K, Schleicher, Krista, Malik, Ahmad, Quevedo, Rene, Langille, Ellen, Teng, Katie, Oh, Robin H, Rathod, Bhavisha, Tsai, Ricky, Samavarchi-Tehrani, Payman, Pugh, Trevor J, Gingras, Anne-Claude, Schramek, Daniel

“…In most human cancers, only a few genes are mutated at high frequencies; most are mutated at low frequencies. The functional consequences of these recurrent…”
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Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems by Gollapudi, Sampath K., Yu, Ming, Gan, Qing-Fen, Nag, Suman

“…A hallmark feature of myosin-II is that it can spontaneously self-assemble into bipolar synthetic thick filaments (STFs) in low-ionic-strength buffers, thereby…”
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An efficacious method for detecting phishing webpages through target domain identification by Ramesh, Gowtham, Krishnamurthi, Ilango, Kumar, K. Sampath Sree

“…Phishing is a fraudulent act to acquire sensitive information from unsuspecting users by masking as a trustworthy entity in an electronic commerce. Several…”
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Lack of redundancy between electrophysiological measures of long-range neuronal communication by Strahnen, Daniel, Kapanaiah, Sampath K T, Bygrave, Alexei M, Kätzel, Dennis

“…Communication between brain areas has been implicated in a wide range of cognitive and emotive functions and is impaired in numerous mental disorders. In…”
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Delayed-matching-to-position working memory in mice relies on NMDA-receptors in prefrontal pyramidal cells by Kilonzo, Kasyoka, van der Veen, Bastiaan, Teutsch, Jasper, Schulz, Stefanie, Kapanaiah, Sampath K. T., Liss, Birgit, Kätzel, Dennis

“…A hypofunction of N-methyl-D-aspartate glutamate receptors (NMDARs) has been implicated in the pathogenesis of schizophrenia by clinical and rodent studies…”
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Optimizing time prediction and error classification in early melanoma detection using a hybrid RCNN‐LSTM model by Arjun, K. P., Kumar, K. Sampath, Dhanaraj, Rajesh Kumar, Ravi, Vinayakumar, Kumar, T. Ganesh

“…Skin cancer is a terrifying disorder that affects all individuals. Due to the significant increase in the rate of melanoma skin cancer, early detection of skin…”
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A low-cost open-source 5-choice operant box system optimized for electrophysiology and optophysiology in mice by Kapanaiah, Sampath K. T., van der Veen, Bastiaan, Strahnen, Daniel, Akam, Thomas, Kätzel, Dennis

“…Operant boxes enable the application of complex behavioural paradigms to support circuit neuroscience and drug discovery research. However, commercial operant…”
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Enhanced Cortical Metabolic Activity in Females and Males of a Slow Progressing Mouse Model of Amyotrophic Lateral Sclerosis by Roy, Dipak, Puvvada, Madhuri, Kapanaiah, Sampath K. T., Patel, Anant Bahadur

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with selective degeneration of motor neurons in the central nervous system. The…”
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High strength steel weld metal properties: metallurgical criteria and computational tools by Sampath, K., Varadarajan, R.

“…High-strength steel (HSS) welding electrode specifications based on Fe–C–Mn alloy system offer two sets of tables for compliance, one on specified electrode…”
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Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States by Gollapudi, Sampath K., Ma, Weikang, Chakravarthy, Srinivas, Combs, Ariana C., Sa, Na, Langer, Stephen, Irving, Thomas C., Nag, Suman

“…[Display omitted] •In relaxed cardiac muscle, some myosins exist in energy-sparing off states.•This reserve pool of myosins can be recruited under increased…”
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Acute optogenetic induction of the prodromal endophenotype of CA1 hyperactivity causes schizophrenia-related deficits in cognition and salience attribution by Kapanaiah, Sampath K. T., Grimm, Christina, Kätzel, Dennis

“…Hyperactivity of the human anterior hippocampus has been reported to spread from its CA1 subfield to the subiculum around the onset of first-episode psychosis…”
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Neural effects of dopaminergic compounds revealed by multi-site electrophysiology and interpretable machine-learning by Kapanaiah, Sampath K T, Rosenbrock, Holger, Hengerer, Bastian, Kätzel, Dennis

“…Neuropsychopharmacological compounds may exert complex brain-wide effects due to an anatomically and genetically broad expression of their molecular targets…”
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Mechanistic Study on Thymoquinone Conjugated ZnO Nanoparticles Mediated Cytotoxicity and Anticancer Activity in Triple-Negative Breast Cancer Cells by Banupriya, Sampath K, Kavithaa, Krishnamoorthy, Poornima, Arumugam, Sumathi, Sundaravadivelu

“…In the current era, the development of molecular techniques involves nano techniques, and the synthesis of nanoparticles is considered the preferred field in…”
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Human Corneal Expression of SLC4A11, a Gene Mutated in Endothelial Corneal Dystrophies by Malhotra, Darpan, Loganathan, Sampath K., Chiu, Anthony M., Lukowski, Chris M., Casey, Joseph R.

“…Two blinding corneal dystrophies, pediatric-onset congenital hereditary endothelial dystrophy (CHED) and some cases of late-onset Fuchs endothelial corneal…”
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Omecamtiv Mecarbil Abolishes Length-Mediated Increase in Guinea Pig Cardiac Myofiber Ca2+ Sensitivity by Gollapudi, Sampath K., Reda, Sherif M., Chandra, Murali

“…Omecamtiv mecarbil (OM) is a pharmacological agent that augments cardiac contractile function by enhancing myofilament Ca2+ sensitivity. Given that…”
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Correction to: High strength steel weld metal properties: metallurgical criteria and computational tools by Sampath, K., Varadarajan, R.

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Corneal Dystrophy-Causing SLC4A11 Mutants: Suitability for Folding-Correction Therapy by Loganathan, Sampath K., Casey, Joseph R.

“…ABSTRACT SLC4A11 mutations cause some cases of the corneal endothelial dystrophies, congenital hereditary endothelial corneal dystrophy type 2 (CHED2),…”
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Transmembrane water-flux through SLC4A11: a route defective in genetic corneal diseases by Vilas, Gonzalo L, Loganathan, Sampath K, Liu, Jun, Riau, Andri K, Young, James D, Mehta, Jodhbir S, Vithana, Eranga N, Casey, Joseph R

“…Three genetic corneal dystrophies [congenital hereditary endothelial dystrophy type 2 (CHED2), Harboyan syndrome and Fuchs endothelial corneal dystrophy] arise…”
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LWDS: lightweight DeepSeagrass technique for classifying seagrass from underwater images by Paul, M. Asha, Kumar, K. Sampath, Sagar, Shrddha, Sreeji, S

“…In many coastal areas around the world, the seagrasses provide an essential source of livelihood for many civilizations and support high levels of…”
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The N-Terminal Extension of Cardiac Troponin T Stabilizes the Blocked State of Cardiac Thin Filament by Gollapudi, Sampath K., Mamidi, Ranganath, Mallampalli, Sri Lakshmi, Chandra, Murali

“…Cardiac troponin T (cTnT) is a key component of contractile regulatory proteins. cTnT is characterized by a ∼32 amino acid N-terminal extension (NTE), the…”
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