Search Results - "SALVATORI, Alison"

Neuronostatin acts via GPR107 to increase cAMP-independent PKA phosphorylation and proglucagon mRNA accumulation in pancreatic α-cells by Elrick, Mollisa M, Samson, Willis K, Corbett, John A, Salvatori, Alison S, Stein, Lauren M, Kolar, Grant R, Naatz, Aaron, Yosten, Gina L C

“…Neuronostatin (NST) is a recently described peptide that is produced from the somatostatin preprohormone in pancreatic δ-cells. NST has been shown to increase…”
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Reduction in ATP levels triggers immunoproteasome activation by the 11S (PA28) regulator during early antiviral response mediated by IFNβ in mouse pancreatic β-cells by Freudenburg, Wieke, Gautam, Madhav, Chakraborty, Pradipta, James, Jared, Richards, Jennifer, Salvatori, Alison S, Baldwin, Aaron, Schriewer, Jill, Buller, R Mark L, Corbett, John A, Skowyra, Dorota

“…Autoimmune destruction of insulin producing pancreatic β-cells is the hallmark of type I diabetes. One of the key molecules implicated in the disease onset is…”
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Neuronostatin inhibits glucose-stimulated insulin secretion via direct action on the pancreatic α-cell by Salvatori, Alison S, Elrick, Mollisa M, Samson, Willis K, Corbett, John A, Yosten, Gina L C

“…Neuronostatin is a recently described peptide hormone encoded by the somatostatin gene. We previously showed that intraperitoneal injection of neuronostatin…”
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Homogeneous Insulin and C-Peptide Sensors for Rapid Assessment of Insulin and C-Peptide Secretion by the Islets by HEYDUK, Ewa, MOXLEY, Michael M, SALVATORI, Alison, CORBETT, John A, HEYDUK, Tomasz

“…Glucose-stimulated islet insulin or C-peptide secretion experiments are a fundamental tool for studying and assessing islet function. The goal of this work was…”
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AMP-activated Protein Kinase Attenuates Nitric Oxide-induced β-Cell Death by Meares, Gordon P., Hughes, Katherine J., Jaimes, Kimberly F., Salvatori, Alison S., Rhodes, Christopher J., Corbett, John A.

“…During the initial autoimmune response in type 1 diabetes, islets are exposed to a damaging mix of pro-inflammatory molecules that stimulate the production of…”
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Sustained NF-κB activation and inhibition in β-cells have minimal effects on function and islet transplant outcomes by King, Aileen J F, Guo, Yongjing, Cai, Dongsheng, Hollister-Lock, Jennifer, Morris, Brooke, Salvatori, Alison, Corbett, John A, Bonner-Weir, Susan, Shoelson, Steven E, Weir, Gordon C

“…The activation of the transcription factor NF-κB leads to changes in expression of many genes in pancreatic β-cells. However, the role of NF-κB activation in…”
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Probing the intra‐islet control of beta cell function (1108.3) by Elrick, Mollisa, Yosten, Gina, Salvatori, Alison, Samson, W.K.

“…Neuronostatin (NST) is produced in pancreatic delta cells from the somatostatin preprohormone, and has been shown to inhibit glucose‐stimulated insulin…”
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Hypoglycemia unawareness prevention: Targeting glucagon production by Samson, Willis K, Stein, Lauren M, Elrick, Mollisa, Salvatori, Alison, Kolar, Grant, Corbett, John A, Yosten, Gina L.C

“…Abstract Insulin-dependent individuals with diabetes are at risk for a severe hypoglycemic event that may predispose them to several repeat episodes during…”
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Understanding peptide biology: The discovery and characterization of the novel hormone, neuronostatin by Yosten, Gina L.C., Elrick, Mollisa M., Salvatori, Alison, Stein, Lauren M., Kolar, Grant R., Ren, Jun, Corbett, John A., Samson, Willis K.

“…•Bioinformatic analyses revealed the novel hormone, neuronostatin.•Neuronostatin is encoded in the preprosomatostatin prohormone.•Neuronostatin has biologic…”
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Sustained NF-[kappa]B Activation and Inhibition in [beta]-Cells Have Minimal Effects on Function and Islet Transplant Outcomes by King, Aileen J. F, Guo, Yongjing, Cai, Dongsheng, Hollister-Lock, Jennifer, Morris, Brooke, Salvatori, Alison, Corbett, John A, Bonner-Weir, Susan, Shoelson, Steven E, Weir, Gordon C

“…The activation of the transcription factor NF-[kappa]B leads to changes in expression of many genes in pancreatic [beta]-cells. However, the role of…”
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Reduction in ATP Levels Triggers Immunoproteasome Activation by the 11S by Freudenburg, Wieke, Gautam, Madhav, Chakraborty, Pradipta, James, Jared, Richards, Jennifer, Salvatori, Alison S, Baldwin, Aaron, Schriewer, Jill, Buller, R. Mark L, Corbett, John A, Skowyra, Dorota

“…Autoimmune destruction of insulin producing pancreatic [beta]-cells is the hallmark of type I diabetes. One of the key molecules implicated in the disease…”
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Reduction in ATP Levels Triggers Immunoproteasome Activation by the 11S Regulator during Early Antiviral Response Mediated by IFN[beta] in Mouse Pancreatic [beta]-Cells by Freudenburg, Wieke, Gautam, Madhav, Chakraborty, Pradipta, James, Jared, Richards, Jennifer, Salvatori, Alison S, Baldwin, Aaron, Schriewer, Jill, Buller, R. Mark L, Corbett, John A, Skowyra, Dorota

“…Autoimmune destruction of insulin producing pancreatic [beta]-cells is the hallmark of type I diabetes. One of the key molecules implicated in the disease…”
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Linking a Newly Discovered Hormone with Orphan Receptor Candidates: The Search for a Cognate Ligand by Miller, Geoff, Salvatori, Alison S, Yosten, Gina LC, Samson, Willis K

“…Neuronostatin is a newly identified peptide hormone cleaved from the somatostatin pre‐prohormone. Since neuronostatin is encoded in the somatostatin gene,…”
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New insights into the control of pancreatic islet cell function by Salvatori, Alison Sexton

“…Diabetes is a disease, characterized by the failure of the body to make or use insulin, resulting in improper glucose homeostasis. Insulin, a hormone that…”
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AMP-activated Protein Kinase Attenuates Nitric Oxide-induced β-Cell Death by Gordon P. Meares, Katherine J. Hughes, Kimberly F. Jaimes, Alison S. Salvatori, Christopher J. Rhodes, John A. Corbett

“…During the initial autoimmune response in type 1 diabetes, islets are exposed to a damaging mix of pro-inflammatory molecules that stimulate the production of…”
Get full text