Search Results - "SALOTRA, Poonam"
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Elucidation of Cellular Mechanisms Involved in Experimental Paromomycin Resistance in Leishmania donovani
Published in Antimicrobial agents and chemotherapy (01-05-2014)“…Leishmania donovani is the causative agent of the potentially fatal disease visceral leishmaniasis (VL). Chemotherapeutic options available to treat VL are…”
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Diagnosis of visceral leishmaniasis: developments over the last decade
Published in Parasitology research (1987) (01-03-2012)“…Diagnostic parameters for visceral leishmaniasis (VL), a potentially fatal parasitic disease caused by Leishmania donovani, have been redefined in the last…”
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Clinico-epidemiological analysis of Post kala-azar dermal leishmaniasis (PKDL) cases in India over last two decades: a hospital based retrospective study
Published in BMC public health (26-10-2015)“…Patients with Post kala-azar dermal leishmaniasis (PKDL) are considered a reservoir of Leishmania donovani. It is imperative to identify and treat them early…”
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Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress
Published in PLoS neglected tropical diseases (02-06-2017)“…Miltefosine (MIL) is an oral antileishmanial drug used for treatment of visceral leishmaniasis (VL) in the Indian subcontinent. Recent reports indicate a…”
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Validation of SYBR green I based closed tube loop mediated isothermal amplification (LAMP) assay and simplified direct-blood-lysis (DBL)-LAMP assay for diagnosis of visceral leishmaniasis (VL)
Published in PLoS neglected tropical diseases (01-11-2018)“…The World Health Organization has targeted elimination of visceral leishmaniasis (VL) in the Indian subcontinent (ISC) by 2020. Despite distinctive decline…”
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Quantification of parasite load in clinical samples of leishmaniasis patients: IL-10 level correlates with parasite load in visceral leishmaniasis
Published in PloS one (09-04-2010)“…A rapid and accurate method to detect and quantify Leishmania parasite is urgently needed to facilitate early diagnosis of leishmaniasis and monitoring of…”
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Development of a rapid loop-mediated isothermal amplification assay for diagnosis and assessment of cure of Leishmania infection
Published in BMC infectious diseases (23-03-2017)“…Leishmaniasis is a spectrum of diseases with great relevance to public health. Conventional diagnostic methods are time consuming, needing trained personnel. A…”
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In Vitro Susceptibility of Field Isolates of Leishmania donovani to Miltefosine and Amphotericin B: Correlation with Sodium Antimony Gluconate Susceptibility and Implications for Treatment in Areas of Endemicity
Published in Antimicrobial Agents and Chemotherapy (01-02-2009)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Decline in Clinical Efficacy of Oral Miltefosine in Treatment of Post Kala-azar Dermal Leishmaniasis (PKDL) in India
Published in PLoS neglected tropical diseases (01-10-2015)“…Recent studies have shown significant decline in the final cure rate after miltefosine treatment in visceral leishmaniasis. This study evaluates the efficacy…”
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Manufacturing and preclinical toxicity of GLP grade gene deleted attenuated Leishmania donovani parasite vaccine
Published in Scientific reports (25-06-2024)“…Centrin1 gene deleted Leishmania donovani parasite ( LdCen1 −/− ) was developed and extensively tested experimentally as an intracellular stage-specific…”
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Application of loop-mediated isothermal amplification assay for the sensitive and rapid diagnosis of visceral leishmaniasis and post-kala-azar dermal leishmaniasis
Published in Diagnostic microbiology and infectious disease (01-04-2013)“…Abstract Loop-mediated isothermal amplification (LAMP) is at the forefront in the search for innovative diagnostics for rapid and specific amplification of…”
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Advancement in molecular diagnosis of post kala-azar dermal leishmaniasis
Published in Indian journal of dermatology (01-11-2020)“…Post kala-azar dermal leishmaniasis (PKDL), a clinical sequela of visceral leishmaniasis (VL), plays a critical role in the anthroponotic transmission of VL,…”
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Antimony susceptible Leishmania donovani : evidence from in vitro drug susceptibility of parasites isolated from patients of post-kala-azar dermal leishmaniasis in pre- and post-miltefosine era
Published in Microbiology spectrum (07-05-2024)“…Post-kala-azar dermal leishmaniasis (PKDL) patients are a key source of parasites, hindering the goal of eliminating visceral leishmaniasis (VL). Monitoring…”
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Drug susceptibility in Leishmania isolates following miltefosine treatment in cases of visceral leishmaniasis and post kala-azar dermal leishmaniasis
Published in PLoS neglected tropical diseases (01-05-2012)“…With widespread resistance to antimonials in Visceral Leishmaniasis (VL) in the Indian subcontinent, Miltefosine (MIL) has been introduced as the first line…”
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Reliable diagnosis of post‐kala‐azar dermal leishmaniasis (PKDL) using slit aspirate specimen to avoid invasive sampling procedures
Published in Tropical medicine & international health (01-03-2013)“…Objective Confirmatory diagnosis of post‐kala‐azar dermal leishmaniasis (PKDL) is primarily based on invasive skin biopsy procedure. We evaluated the utility…”
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Foxp3 and IL-10 expression correlates with parasite burden in lesional tissues of post kala azar dermal leishmaniasis (PKDL) patients
Published in PLoS neglected tropical diseases (01-05-2011)“…Post kala-azar dermal leishmaniasis (PKDL), a sequel to visceral leishamaniasis (VL) in 5-15% cases, constitutes a parasite reservoir important in disease…”
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Evidence for involvement of Th17 type responses in post kala azar dermal leishmaniasis (PKDL)
Published in PLoS neglected tropical diseases (01-06-2012)“…Post kala-azar dermal leishmaniasis (PKDL), a dermal sequel of visceral leishmaniasis, caused by Leishmania donovani, constitutes an important reservoir for…”
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Proteomic Analysis of Leishmania donovani Membrane Components Reveals the Role of Activated Protein C Kinase in Host-Parasite Interaction
Published in Pathogens (Basel) (15-09-2021)“…Visceral leishmaniasis (VL), mainly caused by the Leishmania donovani parasitic infection, constitutes a potentially fatal disease, for which treatment is…”
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Antimony-Resistant Clinical Isolates of Leishmania donovani Are Susceptible to Paromomycin and Sitamaquine
Published in Antimicrobial Agents and Chemotherapy (01-06-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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20
In vitro evaluation of a soluble Leishmania promastigote surface antigen as a potential vaccine candidate against human leishmaniasis
Published in PloS one (02-05-2014)“…PSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and secreted proteins present in several Leishmania (L.) species. PSA is recognized by…”
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