Search Results - "SALMOND, GEORGE"

A century of the phage: past, present and future by Salmond, George P. C., Fineran, Peter C.

“…Phages were discovered 100 years ago, and since then phage research has transformed fundamental and translational biosciences. In this Timeline, Salmond and…”
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Combating Multidrug-Resistant Bacteria: Current Strategies for the Discovery of Novel Antibacterials by O'Connell, Kieron M. G., Hodgkinson, James T., Sore, Hannah F., Welch, Martin, Salmond, George P. C., Spring, David R.

“…The introduction of effective antibacterial therapies for infectious diseases in the mid‐20th century completely revolutionized clinical practices and helped…”
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phage abortive infection system, ToxIN, functions as a protein-RNA toxin-antitoxin pair by Fineran, Peter C, Blower, Tim R, Foulds, Ian J, Humphreys, David P, Lilley, Kathryn S, Salmond, George P.C

“…Various mechanisms exist that enable bacteria to resist bacteriophage infection. Resistance strategies include the abortive infection (Abi) systems, which…”
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A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism by Dy, Ron L, Przybilski, Rita, Semeijn, Koen, Salmond, George P C, Fineran, Peter C

“…Bacterial abortive infection (Abi) systems are 'altruistic' cell death systems that are activated by phage infection and limit viral replication, thereby…”
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Viral evasion of a bacterial suicide system by RNA-based molecular mimicry enables infectious altruism by Blower, Tim R, Evans, Terry J, Przybilski, Rita, Fineran, Peter C, Salmond, George P C

“…Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal…”
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The biosynthesis and regulation of bacterial prodiginines by Salmond, George P. C, Williamson, Neil R, Fineran, Peter C, Leeper, Finian J

“…The red-pigmented prodiginines are bioactive secondary metabolites produced by both Gram-negative and Gram-positive bacteria. Recently, these tripyrrole…”
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Sense codon reassignment enables viral resistance and encoded polymer synthesis by Robertson, Wesley E., Funke, Louise F. H., de la Torre, Daniel, Fredens, Julius, Elliott, Thomas S., Spinck, Martin, Christova, Yonka, Cervettini, Daniele, Böge, Franz L., Liu, Kim C., Buse, Salvador, Maslen, Sarah, Salmond, George P. C., Chin, Jason W.

“…Designing bacterial superpowers Biological systems read all 64 triplet codons in DNA to encode the synthesis of proteins composed of 20 canonical amino acids…”
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Quorum sensing coordinates brute force and stealth modes of infection in the plant pathogen Pectobacterium atrosepticum by Liu, Hui, Coulthurst, Sarah J, Pritchard, Leighton, Hedley, Peter E, Ravensdale, Michael, Humphris, Sonia, Burr, Tom, Takle, Gunnhild, Brurberg, May-Bente, Birch, Paul R J, Salmond, George P C, Toth, Ian K

“…Quorum sensing (QS) in vitro controls production of plant cell wall degrading enzymes (PCWDEs) and other virulence factors in the soft rotting enterobacterial…”
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Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems by Patterson, Adrian G., Jackson, Simon A., Taylor, Corinda, Evans, Gary B., Salmond, George P.C., Przybilski, Rita, Staals, Raymond H.J., Fineran, Peter C.

“…Bacteria commonly exist in high cell density populations, making them prone to viral predation and horizontal gene transfer (HGT) through transformation and…”
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Molecular genetic and physical analysis of gas vesicles in buoyant enterobacteria by Tashiro, Yosuke, Monson, Rita E, Ramsay, Joshua P, Salmond, George P. C

“…Different modes of bacterial taxis play important roles in environmental adaptation, survival, colonization and dissemination of disease. One mode of taxis is…”
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The bacterial Type III toxin-antitoxin system, ToxIN, is a dynamic protein-RNA complex with stability-dependent antiviral abortive infection activity by Short, Francesca L., Akusobi, Chidiebere, Broadhurst, William R., Salmond, George P. C.

“…Bacteria have evolved numerous defense systems to protect themselves from viral (bacteriophage) infection. The ToxIN system of Pectobacterium atrosepticum is a…”
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Bacteriophage host range evolution through engineered enrichment bias, exploiting heterologous surface receptor expression by Zeng, Ziyue, Salmond, George P. C.

“…Summary Research on the initial phage–host interaction has been conducted on a limited repertoire of phages and their cognate receptors, such as phage λ and…”
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Microbial gas vesicles as nanotechnology tools: exploiting intracellular organelles for translational utility in biotechnology, medicine and the environment by Hill, Amy M, Salmond, George P C

“…A range of bacteria and archaea produce gas vesicles as a means to facilitate flotation. These gas vesicles have been purified from a number of species and…”
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Dickeya solani by Matilla, Miguel A., Monson, Rita E., Salmond, George P.C.

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Refactored genetic codes enable bidirectional genetic isolation by Zürcher, Jérôme F, Robertson, Wesley E, Kappes, Tomás, Petris, Gianluca, Elliott, Thomas S, Salmond, George P C, Chin, Jason W

“…The near-universal genetic code defines the correspondence between codons in genes and amino acids in proteins. We refactored the structure of the genetic code…”
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Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity by Watson, Bridget N. J., Vercoe, Reuben B., Salmond, George P. C., Westra, Edze R., Staals, Raymond H. J, Fineran, Peter C.

“…Type I CRISPR-Cas systems are abundant and widespread adaptive immune systems in bacteria and can greatly enhance bacterial survival in the face of phage…”
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PigS and PigP Regulate Prodigiosin Biosynthesis in Serratia via Differential Control of Divergent Operons, Which Include Predicted Transporters of Sulfur-Containing Molecules by GRISTWOOD, Tamzin, MCNEIL, Matthew B, CLULOW, James S, SALMOND, George P. C, FINERAN, Peter C

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Remarkable Mechanisms in Microbes to Resist Phage Infections by Dy, Ron L, Richter, Corinna, Salmond, George P C, Fineran, Peter C

“…Bacteriophages (phages) specifically infect bacteria and are the most abundant biological entities on Earth. The constant exposure to phage infection imposes a…”
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Evolution of Pectobacterium Bacteriophage ΦM1 To Escape Two Bifunctional Type III Toxin-Antitoxin and Abortive Infection Systems through Mutations in a Single Viral Gene by Blower, Tim R, Chai, Ray, Przybilski, Rita, Chindhy, Shahzad, Fang, Xinzhe, Kidman, Samuel E, Tan, Hui, Luisi, Ben F, Fineran, Peter C, Salmond, George P C

“…Some bacteria, when infected by their viral parasites (bacteriophages), undergo a suicidal response that also terminates productive viral replication (abortive…”
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Biotechnological exploitation of bacteriophage research by Petty, Nicola K, Evans, Terry J, Fineran, Peter C, Salmond, George P.C

“…The experimentally amenable nature of phage and their use in testing fundamental biological questions have meant that phage research has had a profound effect…”
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