Search Results - "SALERNO, Alessandro G"

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1 by Ramirez, Cristina M, Dávalos, Alberto, Goedeke, Leigh, Salerno, Alessandro G, Warrier, Nikhil, Cirera-Salinas, Daniel, Suárez, Yajaira, Fernández-Hernando, Carlos

“…OBJECTIVE—The ATP-binding cassette transporter A1 (ABCA1) is a major regulator of macrophage cholesterol efflux and protects cells from excess intracellular…”
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Mir-33 regulates cell proliferation and cell cycle progression by Cirera-Salinas, Daniel, Pauta, Montse, Allen, Ryan M., Salerno, Alessandro G., Ramírez, Cristina M., Chamorro-Jorganes, Aranzazu, Wanschel, Amarylis C., Lasuncion, Miguel A., Morales-Ruiz, Manuel, Suarez, Yajaira, Baldan, Angel, Esplugues, Enric, Fernández-Hernando, Carlos

“…Cholesterol metabolism is tightly regulated at the cellular level and is essential for cellular growth. microRNAs (miRNAs), a class of noncoding RNAs, have…”
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Generation of SARS-CoV-2 Spike Pseudotyped Virus for Viral Entry and Neutralization Assays: A 1-Week Protocol by Condor Capcha, Jose Manuel, Lambert, Guerline, Dykxhoorn, Derek M, Salerno, Alessandro G, Hare, Joshua M, Whitt, Michael A, Pahwa, Savita, Jayaweera, Dushyantha T, Shehadeh, Lina A

“…The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus requires reliable assays for studying viral entry mechanisms which remains poorly understood. This…”
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Hematopoietic Akt2 deficiency attenuates the progression of atherosclerosis by Rodlan, Noemi, Chamorro‐Jorganes, Aránzazu, Araldi, Elisa, Wanschel, Amarylis C., Aryal, Binod, Aranda, Juan F., Goedeke, Leigh, Salerno, Alessandro G., Ramírez, Cristina M., Sessa, William C., Suárez, Yajaira, Fernández‐Hernando, Carlos

“…ABSTRACT Atherosclerosis is the major cause of death and disability in diabetic and obese subjects with insulin resistance. Akt2, a phosphoinositide‐dependent…”
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The Presence of Cholesteryl Ester Transfer Protein (CETP) in Endothelial Cells Generates Vascular Oxidative Stress and Endothelial Dysfunction by Wanschel, Amarylis C B A, Guizoni, Daniele M, Lorza-Gil, Estela, Salerno, Alessandro G, Paiva, Adriene A, Dorighello, Gabriel G, Davel, Ana Paula, Balkan, Wayne, Hare, Joshua M, Oliveira, Helena C F

“…Endothelial dysfunction precedes atherosclerosis and is an independent predictor of cardiovascular events. Cholesterol levels and oxidative stress are key…”
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LDL Receptor Pathway Regulation by miR-224 and miR-520d by Salerno, Alessandro G., van Solingen, Coen, Scotti, Elena, Wanschel, Amarylis C. B. A., Afonso, Milessa S., Oldebeken, Scott R., Spiro, Westley, Tontonoz, Peter, Rayner, Katey J., Moore, Kathryn J.

“…MicroRNAs (miRNA) have emerged as important post-transcriptional regulators of metabolic pathways that contribute to cellular and systemic lipoprotein…”
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High-Throughput Screening Identifies MicroRNAs Regulating Human PCSK9 and Hepatic Low-Density Lipoprotein Receptor Expression by van Solingen, Coen, Oldebeken, Scott R., Salerno, Alessandro G., Wanschel, Amarylis C. B. A., Moore, Kathryn J.

“…Investigations into the regulatory mechanisms controlling cholesterol homeostasis have proven fruitful in identifying low-density lipoprotein (LDL)-lowering…”
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Oxidative stress in atherosclerosis‐prone mouse is due to low antioxidant capacity of mitochondria by Oliveira, C. F. Helena, Cosso, G. Ricardo, Alberici, C. Luciane, Maciel, N. Evelise, Salerno, G. Alessandro, Dorighello, G. Gabriel, Velho, A. Jesus, De Faria, Eliana C., Vercesi, Anibal E.

“…ABSTRACT Atherosclerotic disease remains a leading cause of death in westernized societies, and reactive oxygen species (ROS) play a pivotal role in…”
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Cholesteryl ester transfer protein (CETP) increases postprandial triglyceridaemia and delays triacylglycerol plasma clearance in transgenic mice by Salerno, Alessandro G, Patrício, Patrícia R, Berti, Jairo A, Oliveira, Helena C F

“…The CETP (cholesteryl ester transfer protein) is a plasma protein synthesized in several tissues, mainly in the liver; CETP reduces plasma HDL (high-density…”
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Mechanism of Action of Mesenchymal Stem Cells (MSCs): impact of delivery method by Bagno, Luiza L, Salerno, Alessandro G, Balkan, Wayne, Hare, Joshua M

“…Mesenchymal stromal cells (MSCs; AKA mesenchymal stem cells) stimulate healing and reduce inflammation. Promising therapeutic responses are seen in many…”
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Macrophage-restricted overexpression of glutaredoxin 1 protects against atherosclerosis by preventing nutrient stress-induced macrophage dysfunction and reprogramming by Ahn, Yong Joo, Wang, Luxi, Kim, Seonwook, Eber, Matthew R, Salerno, Alessandro G, Asmis, Reto

“…Deficiency in the thiol transferase glutaredoxin 1 (Grx1) in aging mice promotes, in a sexually dimorphic manner, dysregulation of macrophages and…”
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Synthetic growth hormone-releasing hormone agonist ameliorates the myocardial pathophysiology characteristic of heart failure with preserved ejection fraction by Dulce, Raul A, Kanashiro-Takeuchi, Rosemeire M, Takeuchi, Lauro M, Salerno, Alessandro G, Wanschel, Amarylis C B A, Kulandavelu, Shathiyah, Balkan, Wayne, Zuttion, Marilia S S R, Cai, Renzhi, Schally, Andrew V, Hare, Joshua M

“…To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signalling pathway within the myocardium both prevents and…”
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Genetic Evidence Supports a Major Role for Akt1 in VSMCs During Atherogenesis by Rotllan, Noemi, Wanschel, Amarylis C, Fernández-Hernando, Ana, Salerno, Alessandro G, Offermanns, Stefan, Sessa, William C, Fernández-Hernando, Carlos

“…RATIONALE:Coronary artery disease, the direct result of atherosclerosis, is the most common cause of death in Western societies. Vascular smooth muscle cell…”
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Coenzyme Q 10 protects against β-cell toxicity induced by pravastatin treatment of hypercholesterolemia by Lorza-Gil, Estela, de Souza, Jane C, García-Arévalo, Marta, Vettorazzi, Jean F, Marques, Ana Carolina, Salerno, Alessandro G, Trigo, Jose Roberto, Oliveira, Helena C F

“…New onset of diabetes is associated with the use of statins. We have recently demonstrated that pravastatin-treated hypercholesterolemic LDL receptor knockout…”
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Coenzyme Q10 protects against β‐cell toxicity induced by pravastatin treatment of hypercholesterolemia by Lorza‐Gil, Estela, de Souza, Jane C., García‐Arévalo, Marta, Vettorazzi, Jean F., Marques, Ana Carolina, Salerno, Alessandro G., Trigo, Jose Roberto, Oliveira, Helena C. F.

“…New onset of diabetes is associated with the use of statins. We have recently demonstrated that pravastatin‐treated hypercholesterolemic LDL receptor knockout…”
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Chronic use of pravastatin reduces insulin exocytosis and increases β-cell death in hypercholesterolemic mice by Lorza-Gil, Estela, Salerno, Alessandro G, Wanschel, Amarylis C.B.A, Vettorazzi, Jean F, Ferreira, Mônica S, Rentz, Thiago, Catharino, Rodrigo R, Oliveira, Helena C.F

“…Highlights • Hypercholesterolemic mice have reduced insulin secretion. • We hypothesized that pravastatin treatment improves insulin secretion. • Pravastatin…”
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Determination of streptomycin residues in honey by liquid chromatography–tandem mass spectrometry by Granja, Rodrigo H.M.M., Niño, Alfredo M. Montes, Zucchetti, Roberto A.M., Niño, Rosario E. Montes, Patel, Raj, Salerno, Alessandro G.

“…Streptomycin is an aminoglycoside antibiotic used in apiculture to protect bees against a variety of brood diseases. Brazilian authorities have included it in…”
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Determination and confirmation of metronidazole, dimetridazole, ronidazole and their metabolites in bovine muscle by LC-MS/MS by Granja, Rodrigo H.M.M, Nino, Alfredo M.M, Reche, Karine V.G, Giannotti, Fabio M, de Lima, Andreia C, Wanschel, Amarylis C.B.A, Salerno, Alessandro G

“…Nitroimidazoles are a class of veterinary drugs used for the treatment and prevention of certain bacterial and protozoal diseases in poultry, swine dysentery…”
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Laboratory validation of an LC-MS/MS method for the detection of ractopamine, clenbuterol and salbutamol in bovine and swine muscle at sub-μg kg-1 regulatory limits by Montes Nino, Alfredo M., Granja, Rodrigo H. M. M., Reche, Karine V. G., Giannotti, Fabio M., de Souza, João K. G., Ferrari, Sarita P. G., dos Santos, André D., Wanschel, Amarylis C. B. A., Salerno, Alessandro G.

“…Ractopamine (RAC), is a β-adrenergic agonist increasingly used in the swine and cattle industry. This compound redirects nutrients to favour leanness rather…”
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Liquid chromatography/tandem mass spectrometry method to determine boldenone in bovine liver tissues by Granja, Rodrigo H M M, Salerno, Alessandro G, de Lima, Andreia C, Montalvo, Cynthia, Reche, Karine V G, Giannotti, Fabio M, Wanschel, Amarylis C B A

“…Boldenone, an androgenic steroid, is forbidden for use in meat production in most countries worldwide. Residues of this drug in food present a potential risk…”
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