Search Results - "SALBAUM, J. Michael"

Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging by Youm, Yun-Hee, Grant, Ryan W., McCabe, Laura R., Albarado, Diana C., Nguyen, Kim Yen, Ravussin, Anthony, Pistell, Paul, Newman, Susan, Carter, Renee, Laque, Amanda, Münzberg, Heike, Rosen, Clifford J., Ingram, Donald K., Salbaum, J. Michael, Dixit, Vishwa Deep

“…Despite a wealth of clinical data showing an association between inflammation and degenerative disorders in the elderly, the immune sensors that causally link…”
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A map of the PGC-1α- and NT-PGC-1α-regulated transcriptional network in brown adipose tissue by Chang, Ji Suk, Ghosh, Sujoy, Newman, Susan, Salbaum, J. Michael

“…Transcriptional coactivator PGC-1α and its splice variant NT-PGC-1α play crucial roles in regulating cold-induced thermogenesis in brown adipose tissue (BAT)…”
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Maternal obese-type gut microbiota differentially impact cognition, anxiety and compulsive behavior in male and female offspring in mice by Bruce-Keller, Annadora J, Fernandez-Kim, Sun-Ok, Townsend, R Leigh, Kruger, Claudia, Carmouche, Richard, Newman, Susan, Salbaum, J Michael, Berthoud, Hans-Rudolf

“…Maternal obesity is known to predispose offspring to metabolic and neurodevelopmental abnormalities. While the mechanisms underlying these phenomena are…”
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Maternal diet modulates placental nutrient transporter gene expression in a mouse model of diabetic pregnancy by Kappen, Claudia, Kruger, Claudia, Jones, Sydney, Herion, Nils J, Salbaum, J Michael

“…Diabetes in the mother during pregnancy is a risk factor for birth defects and perinatal complications and can affect long-term health of the offspring through…”
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Author Correction: Novel mode of defective neural tube closure in the non-obese diabetic (NOD) mouse strain by Salbaum, J. Michael, Kruger, Claudia, MacGowan, Jacalyn, Herion, Nils J., Burk, David, Kappen, Claudia

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Broad spectrum of CRISPR-induced edits in an embryonic lethal gene by Fuselier, Kayla T. B., Salbaum, J. Michael, Kappen, Claudia

“…Mendelian genetics poses practical limitations on the number of mutant genes that can be investigated simultaneously for their roles in embryonic development…”
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Effects of Maternal Diabetes and Diet on Gene Expression in the Murine Placenta by Kappen, Claudia, Kruger, Claudia, Salbaum, J Michael

“…Adverse exposures during pregnancy have been shown to contribute to susceptibility for chronic diseases in offspring. Maternal diabetes during pregnancy is…”
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Impaired Mitochondrial Fat Oxidation Induces FGF21 in Muscle by Vandanmagsar, Bolormaa, Warfel, Jaycob D., Wicks, Shawna E., Ghosh, Sujoy, Salbaum, J. Michael, Burk, David, Dubuisson, Olga S., Mendoza, Tamra M., Zhang, Jingying, Noland, Robert C., Mynatt, Randall L.

“…Fatty acids are the primary fuel source for skeletal muscle during most of our daily activities, and impaired fatty acid oxidation (FAO) is associated with…”
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Shortened sleep duration impairs adipose tissue adrenergic stimulation of lipolysis in postmenopausal women by Singh, Prachi, Beyl, Robbie A, Stephens, Jacqueline M, Richard, Allison J, Boudreau, Anik, Caitlin Hebert, R, Noland, Robert C, Burk, David H, Ghosh, Sujoy, Staszkiewicz, Jaroslaw, Michael Salbaum, J, Broussard, Josiane L, St-Onge, Marie-Pierre, Ravussin, Eric, Marlatt, Kara L

“…The objective of this study was to examine the changes in adipose tissue lipolytic capacity and insulin signaling in response to shortened sleep duration (SSD)…”
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A dietary isothiocyanate-enriched moringa (Moringa oleifera) seed extract improves glucose tolerance in a high-fat-diet mouse model and modulates the gut microbiome by Jaja-Chimedza, Asha, Zhang, Li, Wolff, Khea, Graf, Brittany L., Kuhn, Peter, Moskal, Kristin, Carmouche, Richard, Newman, Susan, Salbaum, J. Michael, Raskin, Ilya

“…[Display omitted] •Isothiocyanate-rich moringa seed extract improves metabolic health in obese mice.•Moringa seed extract modulates antioxidant and…”
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Neural tube defect genes and maternal diabetes during pregnancy by Salbaum, J. Michael, Kappen, Claudia

“…BACKGROUND: Maternal diabetes during pregnancy is a well‐known teratogen that increases the risk for birth defects, such as neural tube defects (NTDs). We have…”
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Maternal diabetes alters transcriptional programs in the developing embryo by Pavlinkova, Gabriela, Salbaum, J Michael, Kappen, Claudia

“…Maternal diabetes is a well-known risk factor for birth defects, such as heart defects and neural tube defects. The causative molecular mechanisms in the…”
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Fenugreek Counters the Effects of High Fat Diet on Gut Microbiota in Mice: Links to Metabolic Benefit by Bruce-Keller, Annadora J., Richard, Allison J., Fernandez-Kim, Sun-Ok, Ribnicky, David M., Salbaum, J. Michael, Newman, Susan, Carmouche, Richard, Stephens, Jacqueline M.

“…Fenugreek ( Trigonella foenum-graecum ) is an annual herbaceous plant and a staple of traditional health remedies for metabolic conditions including high…”
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Cross-Omics Analysis of Fenugreek Supplementation Reveals Beneficial Effects Are Caused by Gut Microbiome Changes Not Mammalian Host Physiology by Jones, Katarina A, Richard, Allison J, Salbaum, J Michael, Newman, Susan, Carmouche, Richard, Webb, Sara, Bruce-Keller, Annadora J, Stephens, Jacqueline M, Campagna, Shawn R

“…Herbal remedies are increasing in popularity as treatments for metabolic conditions such as obesity and Type 2 Diabetes. One potential therapeutic option is…”
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Aberrant lipid accumulation in the mouse visceral yolk sac resulting from maternal diabetes and obesity by Zhang, Man, Salbaum, J Michael, Jones, Sydney, Burk, David, Kappen, Claudia

“…Maternal diabetes and obesity in pregnancy are well-known risk factors for structural birth defects, including neural tube defects and congenital heart…”
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Differential responses to maternal diabetes in embryo and visceral yolk sac by Salbaum, J Michael, Stone, Kirsten P, Kruger, Claudia, Kappen, Claudia

“…Maternal diabetes during pregnancy is well known to be associated with a higher risk for structural birth defects in the offspring. Recent searches for…”
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Novel Mode of Defective Neural Tube Closure in the Non-Obese Diabetic (NOD) Mouse Strain by Salbaum, J. Michael, Kruger, Claudia, MacGowan, Jacalyn, Herion, Nils J., Burk, David, Kappen, Claudia

“…Failure to close the neural tube results in birth defects, with severity ranging from spina bifida to lethal anencephaly. Few genetic risk factors for neural…”
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Maternal diet modulates placenta growth and gene expression in a mouse model of diabetic pregnancy by Kappen, Claudia, Kruger, Claudia, MacGowan, Jacalyn, Salbaum, J Michael

“…Unfavorable maternal diet during pregnancy can predispose the offspring to diseases later in life, such as hypertension, metabolic syndrome, and obesity…”
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Nutrient Transporter Gene Expression in the Early Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy by Kappen, Claudia, Kruger, Claudia, Jones, Sydney, Salbaum, J Michael

“…Maternal diabetes in early pregnancy increases the risk for birth defects in the offspring, particularly heart, and neural tube defects. While elevated glucose…”
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A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice by Harmacek, Laura, Watkins‐Chow, Dawn E., Chen, Jianfu, Jones, Kenneth L., Pavan, William J., Salbaum, J. Michael, Niswander, Lee

“…ABSTRACT Failure of embryonic neural tube closure results in the second most common class of birth defects known as neural tube defects (NTDs). While NTDs are…”
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