Search Results - "SALAZAR, Anna M"
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Broad activation of the ubiquitin―proteasome system by Parkin is critical for mitophagy
Published in Human molecular genetics (01-05-2011)“…Parkin, an E3 ubiquitin ligase implicated in Parkinson's disease, promotes degradation of dysfunctional mitochondria by autophagy. Using proteomic and cellular…”
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Intestinal barrier dysfunction: an evolutionarily conserved hallmark of aging
Published in Disease models & mechanisms (01-04-2023)“…A major challenge in the biology of aging is to understand how specific age-onset pathologies relate to the overall health of the organism. The integrity of…”
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Journal Article -
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Intestinal Snakeskin Limits Microbial Dysbiosis during Aging and Promotes Longevity
Published in iScience (30-11-2018)“…Intestinal barrier dysfunction is an evolutionarily conserved hallmark of aging, which has been linked to microbial dysbiosis, altered expression of occluding…”
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Regulation of Synaptic Pumilio Function by an Aggregation-Prone Domain
Published in The Journal of neuroscience (13-01-2010)“…We identified Pumilio (Pum), a Drosophila translational repressor, in a computational search for metazoan proteins whose activities might be regulated by…”
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