Search Results - "SAKODA, Tsuyoshi"
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Adaptive response of the heart to long-term anemia induced by iron deficiency
Published in American journal of physiology. Heart and circulatory physiology (01-03-2009)“…Anemia is common in patients with chronic heart failure and an independent predictor of poor prognosis. Chronic anemia leads to left ventricular (LV)…”
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OCT Assessment of Thin-Cap Fibroatheroma Distribution in Native Coronary Arteries
Published in JACC. Cardiovascular imaging (01-02-2010)“…Objectives We evaluated the geographic distribution of thin-cap fibroatheromas (TCFAs) in the coronary arteries using optical coherence tomography (OCT), a…”
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Iron Regulatory Hormone Hepcidin Decreases in Chronic Heart Failure Patients With Anemia
Published in Circulation Journal (01-02-2010)“…Background: The etiology of anemia is still unclear in patients with chronic heart failure (CHF). Hepcidin is an iron regulatory peptide that is synthesized in…”
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Aldosterone induces interleukin-18 through endothelin-1, angiotensin II, Rho/Rho-kinase, and PPARs in cardiomyocytes
Published in American journal of physiology. Heart and circulatory physiology (01-09-2008)“…Aldosterone (Aldo) is recognized as an important risk factor for cardiovascular diseases. IL-18 induces myocardial hypertrophy, loss of contractility of…”
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Deficiency of Nectin-2 Leads to Cardiac Fibrosis and Dysfunction Under Chronic Pressure Overload
Published in Hypertension (Dallas, Tex. 1979) (01-10-2009)“…The intercalated disc, a cell-cell contact site between neighboring cardiac myocytes, plays an important role in maintaining the homeostasis of the heart by…”
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A High-Titer Lentiviral Production System Mediates Efficient Transduction of Differentiated Cells Including Beating Cardiac Myocytes
Published in Journal of molecular and cellular cardiology (01-11-1999)“…Human immunodeficiency virus (HIV, lentivirus) type-1 based vectors have a number of attractive features for gene therapy, including the ability to transduce…”
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The Mechanism of Distinct Diurnal Variations of Renin-Angiotensin System in Aorta and Heart of Spontaneously Hypertensive Rats
Published in Clinical and experimental hypertension (1993) (01-12-2009)“…Diurnal variations in plasminogen activator inhibitor-1 mRNA expression are different between the spontaneously hypertensive rats (SHRs) and the Wistar-Kyoto…”
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Intramuscular gene transfer of interleukin-10 cDNA reduces atherosclerosis in apolipoprotein E-knockout mice
Published in Atherosclerosis (2004)“…Atherosclerosis has a close relationship to inflammation, particularly T helper type 1 lymphocyte (Th1) response. Interleukin-10 (IL-10), is thought to…”
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Requirement of Activation of the Extracellular Signal-regulated Kinase Cascade in Myocardial Cell Hypertrophy
Published in Journal of molecular and cellular cardiology (01-06-2000)“…T. Ueyama, S. Kawashima, T. Sakoda, Y. Rikitake, T. Ishida, M. Kawai, T. Yamashita, S. Ishida, H. Hotta and M. Yokoyama. Requirement of Activation of the…”
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Decrease in Serum Adiponectin Levels in Response to Treatment Predicts Good Prognosis in Acute Decompensated Heart Failure
Published in The journal of clinical hypertension (Greenwich, Conn.) (01-11-2010)“…J Clin Hypertens (Greenwich). Adiponectin is a cardioprotective adipocytokine. Serum adiponectin concentration decreases in patients who are obese but…”
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Circadian gene expression of clock genes and plasminogen activator inhibitor-1 in heart and aorta of spontaneously hypertensive and Wistar–Kyoto rats
Published in Journal of hypertension (01-06-2003)“…OBJECTIVEHeart and aorta possess biologic clocks, but their involvement in genetic hypertension has been unknown. Plasminogen activator inhibitor-1 (PAI-1)…”
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Transplantation of cardiotrophin-1–expressing myoblasts to the left ventricular wall alleviates the transition from compensatory hypertrophy to congestive heart failure in Dahl salt-sensitive hypertensive rats
Published in Journal of the American College of Cardiology (16-06-2004)“…We investigated whether autologous transplantation of skeletal myoblasts (MB) transferred with cardiotrophin-1 (CT-1) gene could retard the transition to heart…”
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Chylomicron Remnants Stimulate Release of Interleukin-1β by THP-1 Cells
Published in Journal of Atherosclerosis and Thrombosis (2006)“…Recent findings suggest that the oxidative modification of low-density lipoproteins (LDL) and an increase in triglyceride-rich lipoprotein particles including…”
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Loop diuretic precipitated beriberi in a patient after pancreaticoduodenectomy: a case report
Published in The American journal of the medical sciences (01-11-2007)“…Upper gastrointestinal tract surgery and diuretic use are 2 unrecognized causes of thiamine (vitamin B1) deficiency. Upper gastrointestinal tract surgery…”
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Low Concentration of Oxidized Low-Density Lipoprotein and Lysophosphatidylcholine Upregulate Constitutive Nitric Oxide Synthase mRNA Expression in Bovine Aortic Endothelial Cells
Published in Circulation research (01-06-1995)“…Endothelium-dependent relaxation is markedly reduced in atherosclerotic arteries. Recently, the endothelium-dependent relaxing factor has been identified as…”
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Serotonin-induced hypercontraction through 5-hydroxytryptamine 1B receptors in atherosclerotic rabbit coronary arteries
Published in Circulation (New York, N.Y.) (06-03-2001)“…Augmented vasoconstriction to serotonin (5-hydroxytryptamine [5-HT]) in atherosclerotic vessels plays a crucial role in the development of myocardial ischemia…”
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The Renin-Angiotensin System Is Involved in the Production of Plasminogen Activator Inhibitor Type 1 by Cultured Endothelial Cells in Response to Chylomicron Remnants
Published in Hypertension Research (01-04-2003)“…Triglyceride-rich lipoproteins have been suggested to promote atherosclerosis. Plasminogen activator inhibitor type 1 (PAI-1) plays an important role in the…”
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Glycogen Synthase Kinase-3β is Involved in the Process of Myocardial Hypertrophy Stimulated by Insulin-Like Growth Factor-1
Published in Circulation Journal (01-03-2004)“…Background Glycogen synthase kinase-3 β (GSK-3β) is involved in many cellular processes, such as metabolism, apoptosis, differentiation and proliferation…”
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