Search Results - "SAKANASHI, Matao"
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Effect of caffeine contained in a cup of coffee on microvascular function in healthy subjects
Published in Journal of pharmacological sciences (01-02-2015)“…Recent epidemiological studies have demonstrated that coffee drinking is associated with reduced mortality of cardiovascular disease. However, its precise…”
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2
Vascular Lipotoxicity: Endothelial Dysfunction via Fatty-Acid-Induced Reactive Oxygen Species Overproduction in Obese Zucker Diabetic Fatty Rats
Published in Endocrinology (Philadelphia) (01-01-2007)“…Vascular endothelial dysfunction has been demonstrated in obesity, but the molecular basis for this link has not been clarified. We examined the role of free…”
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3
Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo
Published in American journal of physiology. Heart and circulatory physiology (01-09-2011)“…An elevation of oxidized forms of tetrahydrobiopterin (BH(4)), especially dihydrobiopterin (BH(2)), has been reported in the setting of oxidative stress, such…”
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Acute effects of intravenous nicorandil on hemodynamics in patients hospitalized with acute decompensated heart failure
Published in Journal of cardiology (01-11-2010)“…Summary Background Nicorandil injection, a potent vasodilator with KATP channel opening action and nitrate-like action, has been used for treatment of unstable…”
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Long-Term Treatment With San’o-Shashin-To, a Kampo Medicine, Markedly Ameliorates Cardiac Ischemia-Reperfusion Injury in Ovariectomized Rats via the Redox-Dependent Mechanism
Published in Circulation Journal (2013)“…Background: Hormone replacement therapy has failed to reduce ischemic cardiovascular events in climacteric women. To explore alternative therapy, we examined…”
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Improvement of impaired endothelial function by tetrahydrobiopterin in stroke-prone spontaneously hypertensive rats
Published in European journal of pharmacology (10-04-2010)“…To investigate the role of tetrahydrobiopterin (BH4), an essential cofactor of nitric oxide synthase, in endothelial function in a model of genetic…”
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Effect of Decreased Levels of Intrinsic Tetrahydrobiopterin on Endothelial Function in Anesthetized Rats
Published in Journal of Pharmacological Sciences (2008)“…Tetrahydrobiopterin (BH4) deficiency has been suggested to be an important factor in vascular endothelial dysfunction. In this study, we investigated the…”
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Increased Bioavailability of Tacrolimus after Rectal Administration in Rats
Published in Biological & Pharmaceutical Bulletin (01-09-2004)“…The oral bioavailability of tacrolimus is low and varies considerably in humans due to first-pass metabolism by cytochrome P450 (CYP) 3A4 and the active efflux…”
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Beneficial effect of tetrahydrobiopterin on ischemia-reperfusion injury in isolated perfused rat hearts
Published in The Journal of thoracic and cardiovascular surgery (01-10-2002)“…Objective: It has recently been proposed that nitric oxide synthase, in the presence of suboptimal levels of tetrahydrobiopterin, an essential cofactor of this…”
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Investigation of low levels of plasma valproic acid concentration following simultaneous administration of sodium valproate and rizatriptan benzoate
Published in Journal of pharmacy and pharmacology (01-03-2007)“…Drug interaction between rizatriptan benzoate, an anti‐migraine agent, and sodium valproate (VPA‐Na), an anticonvulsant, was studied in rats. When rizatriptan…”
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Cardioprotective effects of extracts from Psidium guajava L and Limonium wrightii, Okinawan medicinal plants, against ischemia-reperfusion injury in perfused rat hearts
Published in Pharmacology (01-03-2003)“…The aim of this study was to determine whether the medicinal herbs growing in Okinawa and possessing a radical-scavenging activity would exert cardioprotective…”
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12
EFFECTS OF LANDIOLOL ON MECHANICAL AND METABOLIC CHANGES IN RAT REPERFUSED ISCHAEMIC HEARTS
Published in Clinical and experimental pharmacology & physiology (01-01-2007)Get full text
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COMPARISON OF HAEMODYNAMIC RESPONSES TO CILNIDIPINE AND NICARDIPINE IN AN EXPERIMENTAL MODEL OF ACUTE CONGESTIVE HEART FAILURE
Published in Clinical and experimental pharmacology & physiology (01-08-1998)“…SUMMARY 1. The haemodynamic effects of cilnidipine, a new calcium channel blocker, were examined in a canine model of acute congestive heart failure and were…”
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14
Haemodynamic and haematologic effects of Acanthaster planci venom in dogs
Published in Toxicon (Oxford) (01-10-1994)“…This study was designed to examine haemodynamic and haematologic effects of the crown-of-thorns starfish venom (Acanthaster planci venom: APV) in dogs. Severe…”
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15
Recent advances in cardiac protection
Published in Nihon yakurigaku zasshi (2003)“…In order to protect the heart from unfavorable conditions such as myocardial ischemia or heart failure, it seems necessarily to investigate what components are…”
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Effects of nipradilol on myocardial ischaemia produced by coronary stenosis in dogs
Published in British journal of pharmacology (01-06-1987)“…1 Effects of nipradilol which is a new β‐adrenoceptor blocking agent endowed with nitroglycerin‐like vasodilator actions, its denitrated derivative (denitro…”
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EFFECTS OF LANDIOLOL ON MECHANICAL AND METABOLIC CHANGES IN RAT REPERFUSED ISCHAEMIC HEARTS
Published in Clinical and experimental pharmacology & physiology (01-01-2007)“…SUMMARY 1 The aim of the present study was to clarify the effects of landiolol, a short‐acting selective β1‐adrenoceptor blocking agent, on mechanical and…”
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18
Rapid and simple micro-determination of carvedilol in rat plasma by high-performance liquid chromatography
Published in Journal of chromatography. B, Biomedical sciences and applications (10-09-1999)“…We studied the use of high-performance liquid chromatography (HPLC) with spectrofluorometric detection, using a solid-phase extraction for a simple, rapid and…”
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Relaxation of isolated dog coronary artery induced by propranolol
Published in European journal of pharmacology (05-03-1981)“…The effects of propranolol and atenolol on isolated dog coronary arteries contracted with potassium were investigated in vitro. Propranolol at high…”
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Cardiovascular effects and lethality of venom from nematocysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rats
Published in Toxicon (Oxford) (15-03-2005)“…Haemodynamic effects of saline-extracted venom from nematocysts isolated from Chiropsalmus quadrigatus (Habu-kurage) were studied in anaesthetized rats…”
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