Search Results - "SAKANASHI, Matao"

Refine Results
  1. 1
  2. 2

    Vascular Lipotoxicity: Endothelial Dysfunction via Fatty-Acid-Induced Reactive Oxygen Species Overproduction in Obese Zucker Diabetic Fatty Rats by Chinen, Ichiro, Shimabukuro, Michio, Yamakawa, Ken, Higa, Namio, Matsuzaki, Toshihiro, Noguchi, Katsuhiko, Ueda, Shinichiro, Sakanashi, Matao, Takasu, Nobuyuki

    Published in Endocrinology (Philadelphia) (01-01-2007)
    “…Vascular endothelial dysfunction has been demonstrated in obesity, but the molecular basis for this link has not been clarified. We examined the role of free…”
    Get full text
    Journal Article
  3. 3
  4. 4
  5. 5
  6. 6

    Improvement of impaired endothelial function by tetrahydrobiopterin in stroke-prone spontaneously hypertensive rats by Noguchi, Katsuhiko, Hamadate, Naobumi, Matsuzaki, Toshihiro, Sakanashi, Mayuko, Nakasone, Junko, Sakanashi, Makiko, Tsutsui, Masato, Sakanashi, Matao

    Published in European journal of pharmacology (10-04-2010)
    “…To investigate the role of tetrahydrobiopterin (BH4), an essential cofactor of nitric oxide synthase, in endothelial function in a model of genetic…”
    Get full text
    Journal Article
  7. 7

    Effect of Decreased Levels of Intrinsic Tetrahydrobiopterin on Endothelial Function in Anesthetized Rats by Hamadate, Naobumi, Noguchi, Katsuhiko, Sakanashi, Mayuko, Matsuzaki, Toshihiro, Nakasone, Junko, Sakanashi, Matao

    “…Tetrahydrobiopterin (BH4) deficiency has been suggested to be an important factor in vascular endothelial dysfunction. In this study, we investigated the…”
    Get full text
    Journal Article
  8. 8

    Increased Bioavailability of Tacrolimus after Rectal Administration in Rats by Sakai, Masayuki, Hobara, Norio, Hokama, Nobuo, Kameya, Hiromasa, Ohshiro, Susumu, Sakanashi, Matao, Saitoh, Hiroshi

    Published in Biological & Pharmaceutical Bulletin (01-09-2004)
    “…The oral bioavailability of tacrolimus is low and varies considerably in humans due to first-pass metabolism by cytochrome P450 (CYP) 3A4 and the active efflux…”
    Get full text
    Journal Article
  9. 9

    Beneficial effect of tetrahydrobiopterin on ischemia-reperfusion injury in isolated perfused rat hearts by Yamashiro, Satoshi, Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Miyagi, Kanako, Nakasone, Junko, Sakanashi, Mayuko, Koja, Kageharu, Sakanashi, Matao

    “…Objective: It has recently been proposed that nitric oxide synthase, in the presence of suboptimal levels of tetrahydrobiopterin, an essential cofactor of this…”
    Get full text
    Journal Article
  10. 10

    Investigation of low levels of plasma valproic acid concentration following simultaneous administration of sodium valproate and rizatriptan benzoate by Hokama, Nobuo, Hobara, Norio, Kameya, Hiromasa, Ohshiro, Susumu, Hobara, Narumi, Sakanashi, Matao

    Published in Journal of pharmacy and pharmacology (01-03-2007)
    “…Drug interaction between rizatriptan benzoate, an anti‐migraine agent, and sodium valproate (VPA‐Na), an anticonvulsant, was studied in rats. When rizatriptan…”
    Get full text
    Journal Article
  11. 11
  12. 12
  13. 13

    COMPARISON OF HAEMODYNAMIC RESPONSES TO CILNIDIPINE AND NICARDIPINE IN AN EXPERIMENTAL MODEL OF ACUTE CONGESTIVE HEART FAILURE by Noguchi, Katsuhiko, Matsuzaki, Toshihiro, Koyama, Tomoyuki, Itomine, Tatsushi, Sakanashi, Matao

    “…SUMMARY 1. The haemodynamic effects of cilnidipine, a new calcium channel blocker, were examined in a canine model of acute congestive heart failure and were…”
    Get full text
    Journal Article
  14. 14

    Haemodynamic and haematologic effects of Acanthaster planci venom in dogs by Shiroma, N, Noguchi, K, Matsuzaki, T, Ojiri, Y, Hirayama, K, Sakanashi, M

    Published in Toxicon (Oxford) (01-10-1994)
    “…This study was designed to examine haemodynamic and haematologic effects of the crown-of-thorns starfish venom (Acanthaster planci venom: APV) in dogs. Severe…”
    Get more information
    Journal Article
  15. 15

    Recent advances in cardiac protection by Sakanashi, Matao, Ichihara, Kazuo, Yoshida, Hiroyuki, Kubota, Toru, Tominaga, Ryuji, Noguchi, Katsuhiko, Obata, Toshio

    Published in Nihon yakurigaku zasshi (2003)
    “…In order to protect the heart from unfavorable conditions such as myocardial ischemia or heart failure, it seems necessarily to investigate what components are…”
    Get more information
    Journal Article
  16. 16

    Effects of nipradilol on myocardial ischaemia produced by coronary stenosis in dogs by Noguchi, Katsuhiko, Sakanashi, Matao

    Published in British journal of pharmacology (01-06-1987)
    “…1 Effects of nipradilol which is a new β‐adrenoceptor blocking agent endowed with nitroglycerin‐like vasodilator actions, its denitrated derivative (denitro…”
    Get full text
    Journal Article
  17. 17

    EFFECTS OF LANDIOLOL ON MECHANICAL AND METABOLIC CHANGES IN RAT REPERFUSED ISCHAEMIC HEARTS by Sakanashi, Makiko, Sakanashi, Mayuko, Sugahara, Kazuhiro, Sakanashi, Matao

    “…SUMMARY 1 The aim of the present study was to clarify the effects of landiolol, a short‐acting selective β1‐adrenoceptor blocking agent, on mechanical and…”
    Get full text
    Journal Article
  18. 18

    Rapid and simple micro-determination of carvedilol in rat plasma by high-performance liquid chromatography by Hokama, Nobuo, Hobara, Norio, Kameya, Hiromasa, Ohshiro, Susumu, Sakanashi, Matao

    “…We studied the use of high-performance liquid chromatography (HPLC) with spectrofluorometric detection, using a solid-phase extraction for a simple, rapid and…”
    Get full text
    Journal Article
  19. 19

    Relaxation of isolated dog coronary artery induced by propranolol by Sakanashi, M, Nishi, K

    Published in European journal of pharmacology (05-03-1981)
    “…The effects of propranolol and atenolol on isolated dog coronary arteries contracted with potassium were investigated in vitro. Propranolol at high…”
    Get more information
    Journal Article
  20. 20

    Cardiovascular effects and lethality of venom from nematocysts of the box-jellyfish Chiropsalmus quadrigatus (Habu-kurage) in anaesthetized rats by Noguchi, Katsuhiko, Sakanashi, Mayuko, Matsuzaki, Toshihiro, Nakasone, Junko, Sakanashi, Makiko, Koyama, Tomoyuki, Hamadate, Naobumi, Sakanashi, Matao

    Published in Toxicon (Oxford) (15-03-2005)
    “…Haemodynamic effects of saline-extracted venom from nematocysts isolated from Chiropsalmus quadrigatus (Habu-kurage) were studied in anaesthetized rats…”
    Get full text
    Journal Article