Search Results - "SAKAI Takahiro"

Different DNA methylome, transcriptome and histological features in uterine fibroids with and without MED12 mutations by Maekawa, Ryo, Sato, Shun, Tamehisa, Tetsuro, Sakai, Takahiro, Kajimura, Takuya, Sueoka, Kotaro, Sugino, Norihiro

“…Somatic mutations in Mediator complex subunit 12 (MED12m) have been reported as a biomarker of uterine fibroids (UFs). However, the role of MED12m is still…”
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Distinct Subcellular Compartments of Dendritic Cells Used for Cross-Presentation by Imai, Jun, Otani, Mayu, Sakai, Takahiro

“…Dendritic cells (DCs) present exogenous protein-derived peptides on major histocompatibility complex class I molecules to prime naïve CD8 T cells. This DC…”
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Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping by Sakai, Takahiro, Mashima, Tsuyoshi, Kobayashi, Naoya, Ogata, Hideaki, Duan, Lian, Fujiki, Ryo, Hengphasatporn, Kowit, Uda, Taizo, Shigeta, Yasuteru, Hifumi, Emi, Hirota, Shun

“…Overexpression of antibody light chains in small plasma cell clones can lead to misfolding and aggregation. On the other hand, the formation of amyloid fibrils…”
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A Case of Cardiac Arrest Caused by Vasovagal Reflex during Blepharoplasty under Local Anesthesia by Fujita, Kengo, Kondoh, Shoji, Sakai, Takahiro, Kitabayashi, Hiroshi, Nishioka, Hiroshi, Yuzuriha, Shunsuke

“…Vasovagal reflex may cause benign self-limiting syncope triggered by factors such as pain and emotional stress. However, rarely, it may cause cardiac arrest…”
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Hydrogen Indirectly Suppresses Increases in Hydrogen Peroxide in Cytoplasmic Hydroxyl Radical-Induced Cells and Suppresses Cellular Senescence by Sakai, Takahiro, Kurokawa, Ryosuke, Hirano, Shin-Ichi, Imai, Jun

“…Bacteria inhabiting the human gut metabolize microbiota-accessible carbohydrates (MAC) contained in plant fibers and subsequently release metabolic products…”
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Prognostic ability of mid-term worsening renal function after percutaneous coronary intervention: findings from the SHINANO registry by Okina, Yoshiteru, Miura, Takashi, Senda, Keisuke, Taki, Minami, Kobayashi, Masanori, Kanai, Masafumi, Okuma, Yukari, Yanagisawa, Takashi, Hashizume, Naoto, Otagiri, Kyuhachi, Shoin, Kyoko, Watanabe, Noboru, Ebisawa, Soichiro, Karube, Kenichi, Nakajima, Hiroyuki, Saigusa, Tatsuya, Miyashita, Yusuke, Kashiwagi, Daisuke, Machida, Keisuke, Abe, Naoyuki, Tachibana, Takahiro, Kanzaki, Yusuke, Maruyama, Takuya, Nomi, Hidetomo, Sakai, Takahiro, Yui, Hisanori, Mochidome, Tomoaki, Kobayashi, Takahiro, Kasai, Toshio, Ikeda, Uichi, Kuwahara, Koichiro

“…Chronic kidney disease is a prognostic factor for cardiovascular disease. Worsening renal function (WRF), specifically, is an important predictor of mortality…”
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The novel antioxidant TA293 reveals the role of cytoplasmic hydroxyl radicals in oxidative stress-induced senescence and inflammation by Sakai, Takahiro, Imai, Jun, Ito, Tomohiro, Takagaki, Hidetsugu, Ui, Michio, Hatta, Shinichi

“…The hydroxyl radical (OH) possesses the strongest oxidation potential among reactive oxygen species (ROS). Hydroxyl radicals react nonpreferentially with…”
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Epicardial Stone　― Unfamiliar Calcified Mass at the Site of Left Ventricular Old Myocardial Infarction by Tabata, Hiroaki, Motoki, Hirohiko, Sakai, Takahiro, Okada, Ayako, Kuwahara, Koichiro

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An optical and non‐invasive method to detect the accumulation of ubiquitin chains by Imai, Jun, Koganezawa, Yuuta, Tuzuki, Haruka, Ishikawa, Ikumi, Sakai, Takahiro

“…The accumulations of excess amounts of polyubiquitinated proteins are cytotoxic and frequently observed in pathologic tissue from patients of neurodegenerative…”
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Prognostic usefulness of residual SYNTAX score combined with clinical factors for patients with acute coronary syndrome who underwent percutaneous coronary intervention from the SHINANO Registry by Kashiwagi, Daisuke, Ebisawa, Soichiro, Yui, Hisanori, Maruyama, Shusaku, Nagae, Ayumu, Sakai, Takahiro, Kato, Tamon, Saigusa, Tatsuya, Okada, Ayako, Motoki, Hirohiko, Kuwahara, Koichiro

“…The optimal strategy for percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) with multi-vessel disease (MVD) is still controversial…”
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Gender difference in heart failure with preserved ejection fraction: clinical profiles, examinations, and prognosis by Sakai, Takahiro, Motoki, Hirohiko, Suzuki, Sho, Fuchida, Aya, Takeuchi, Takahiro, Otagiri, Kyuhachi, Kanai, Masafumi, Kimura, Kazuhiro, Minamisawa, Masatoshi, Yoshie, Koji, Saigusa, Tatsuya, Ebisawa, Soichiro, Okada, Ayako, Kitabayashi, Hiroshi, Kuwahara, Koichiro

“…Heart failure with preserved ejection fraction (HFpEF) has currently become a major concern in the aging society owing to its substantial and growing…”
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Predictive Value of Abdominal Fat Distribution on Coronary Artery Disease Severity Stratified by Computed Tomography-Derived SYNTAX Score by Otagiri, Kyuhachi, Machida, Keisuke, Itagaki, Tadashi, Takeuchi, Takahiro, Tsujinaka, Yusuke, Yui, Hisanori, Nakamura, Chie, Sakai, Takahiro, Kato, Tamon, Saigusa, Tatsuya, Ebisawa, Soichiro, Motoki, Hirohiko, Kuwahara, Koichiro, Kitabayashi, Hiroshi

“…This study aimed to evaluate the association between abdominal fat distribution (AFD) and coronary artery disease (CAD) complexities using the computed…”
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Endoplasmic Reticulum-Associated Degradation-Dependent Processing in Cross-Presentation and Its Potential for Dendritic Cell Vaccinations: A Review by Imai, Jun, Ohashi, Sayaka, Sakai, Takahiro

“…While the success of dendritic cell (DC) vaccination largely depends on cross-presentation (CP) efficiency, the precise molecular mechanism of CP is not yet…”
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Structural Characterization of a Cyclodextrin/l-menthol Inclusion Complex in the Solid-state by Solid-state NMR and Vibrational Circular Dichroism by SAKAI, Takahiro, AKAGI, Yumiko, SUZUKI, Hisashi, IRIE, Mitsuki, NAKAMURA, Tetsuya, SATO, Hisako, KAWAMURA, Izuru

“…Hydrophobic and volatile flavor molecules can be encapsulated inside cyclodextrins (CyDs). Inclusion complexes are frequently used in solid or dispersed states…”
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Enhancing emulsion stability and adsorption of Pickering emulsions using alkylated cellulose nanofibers by Tanzawa, Miyu, Kanai, Noriko, Sakai, Takahiro, Yamada, Kohei, Kumagai, Sari, Mijiddorj, Batsaikhan, Kawamura, Izuru

“…Cellulose nanofibers (CNFs) extracted from plant cell walls form a three-dimensional network in water and stabilize the dispersion of droplets, which are used…”
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Comparison of prognostic impact of anticoagulants in heart failure patients with atrial fibrillation and renal dysfunction: direct oral anticoagulants versus vitamin K antagonists by Sakai, Takahiro, Motoki, Hirohiko, Fuchida, Aya, Takeuchi, Takahiro, Otagiri, Kyuhachi, Kanai, Masafumi, Kimura, Kazuhiro, Minamisawa, Masatoshi, Yoshie, Koji, Saigusa, Tatsuya, Ebisawa, Soichiro, Okada, Ayako, Kitabayashi, Hiroshi, Kuwahara, Koichiro

“…Although high thromboembolic risk was assumed in elderly patients with heart failure (HF) and atrial fibrillation (AF), inadequate control of prothrombin…”
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Impact of changes in body mass index after percutaneous coronary intervention on long-term outcomes in patients with coronary artery disease by Yui, Hisanori, Ebisawa, Soichiro, Miura, Takashi, Nakamura, Chie, Maruyama, Shusaku, Kashiwagi, Daisuke, Nagae, Ayumu, Sakai, Takahiro, Kato, Tamon, Saigusa, Tatsuya, Okada, Ayako, Motoki, Hirohiko, Kuwahara, Koichiro

“…Little is known about the impact of changes in body mass index (BMI) after the percutaneous coronary intervention (PCI) on long-term outcomes in patients with…”
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Impact of nutritional index on long-term outcomes of elderly patients with coronary artery disease: sub-analysis of the SHINANO 5 year registry by Maruyama, Shusaku, Ebisawa, Souichiro, Miura, Takashi, Yui, Hisanori, Kashiwagi, Daisuke, Nagae, Ayumu, Sakai, Takahiro, Kato, Tamon, Saigusa, Tatsuya, Okada, Ayako, Motoki, Hirohiko, Kuwahara, Koichiro

“…Nutritional status is a novel approach to prognostic assessment in patients with cardiovascular disease. However, assessment of nutritional status in elderly…”
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Association between complete revascularization of the coronary artery and clinical outcomes in peripheral artery disease: a sub-analysis of the I-PAD Nagano registry by Kato, Tamon, Ueki, Yasushi, Minamisawa, Masatoshi, Miura, Takashi, Oyama, Yushi, Hashizume, Naoto, Yokota, Daisuke, Taki, Minami, Senda, Keisuke, Okina, Yoshiteru, Wakabayashi, Tadamasa, Fujimori, Koki, Karube, Kenichi, Sakai, Takahiro, Nomi, Hidetomo, Yui, Hisanori, Kanzaki, Yusuke, Machida, Keisuke, Maruyama, Shusaku, Nagae, Ayumu, Saigusa, Tatsuya, Ebisawa, Soichiro, Okada, Ayako, Motoki, Hirohiko, Kuwahara, Koichiro

“…Peripheral artery disease (PAD) is commonly caused by atherosclerosis and has an unfavorable prognosis. Complete revascularization (CR) of the coronary artery…”
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Intensive exercise therapy for restenosis after superficial femoral artery stenting: the REASON randomized clinical trial by Kato, Tamon, Miura, Takashi, Yamamoto, Shuhei, Miyashita, Yusuke, Hashizume, Naoto, Shoin, Kyoko, Sasaki, Shinya, Kanzaki, Yusuke, Yui, Hisanori, Maruyama, Shusaku, Nagae, Ayumu, Sakai, Takahiro, Saigusa, Tatsuya, Ebisawa, Soichiro, Okada, Ayako, Motoki, Hirohiko, Ikeda, Uichi, Kuwahara, Koichiro

“…Endovascular treatment (EVT) is the main treatment for peripheral artery disease (PAD). Despite advances in device development, the restenosis rate remains…”
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