Search Results - "SAITO, ATSUSHI"
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ER Stress and Disease: Toward Prevention and Treatment
Published in Biological & pharmaceutical bulletin (2017)“…Secretory and membrane proteins are synthesized in ribosomes, then mature in the endoplasmic reticulum (ER), but if ER function is impaired, immature defective…”
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2
CREB3L1/OASIS: cell cycle regulator and tumor suppressor
Published in The FEBS journal (01-11-2024)“…Cell cycle checkpoints detect DNA errors, eventually arresting the cell cycle to promote DNA repair. Failure of such cell cycle arrest causes aberrant cell…”
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3
Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue
Published in Scientific reports (12-11-2012)“…Adipose tissue plays a central role in maintaining metabolic homeostasis under normal conditions. Metabolic diseases such as obesity and type 2 diabetes are…”
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4
Ultrasensitive detection of SARS-CoV-2 nucleocapsid protein using large gold nanoparticle-enhanced surface plasmon resonance
Published in Scientific reports (20-01-2022)“…The COVID-19 pandemic has created urgent demand for rapid detection of the SARS-CoV-2 coronavirus. Herein, we report highly sensitive detection of SARS-CoV-2…”
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5
Therapeutic effect of long-acting muscarinic antagonist for treating uncontrolled asthma assessed using impulse oscillometry
Published in Respiratory research (07-08-2024)“…In recent years, the incorporation of LAMAs into asthma therapy has been expected to enhance symptom control. However, a significant number of patients with…”
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6
Unfolded Protein Response-Dependent Communication and Contact among Endoplasmic Reticulum, Mitochondria, and Plasma Membrane
Published in International journal of molecular sciences (18-10-2018)“…The function of the endoplasmic reticulum (ER) can be impaired by changes to the extra- and intracellular environment, such as disruption of calcium…”
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7
Multivesicular body formation enhancement and exosome release during endoplasmic reticulum stress
Published in Biochemical and biophysical research communications (11-11-2016)“…The endoplasmic reticulum (ER) plays a pivotal role in maintaining cellular homeostasis. However, numerous environmental and genetic factors give rise to ER…”
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Impact of Nuclear Envelope Stress on Physiological and Pathological Processes in Central Nervous System
Published in Neurochemical research (01-09-2022)“…The nuclear envelope (NE) separates genomic DNA from the cytoplasm and provides the molecular platforms for nucleocytoplasmic transport, higher-order chromatin…”
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Diverse functions of protein tyrosine phosphatase σ in the nervous and immune systems
Published in Experimental neurology (01-04-2018)“…Tyrosine phosphorylation is a common means of regulating protein functions and signal transduction in multiple cells. Protein tyrosine phosphatases (PTPs) are…”
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10
Auditory interaction between runners: Does footstep sound affect step frequency of neighboring runners?
Published in PloS one (06-01-2023)“…This study aimed to investigate the effect of footsteps of a neighboring runner (NR) on the main runner's step frequency (SF), heart rate (HR), and rating of…”
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The response of the neuronal activity in the somatosensory cortex after high-intensity intermediate-frequency magnetic field exposure to the spinal cord in rats under anesthesia and waking states
Published in Brain research (15-11-2020)“…•High-intensity burst-type IF-MF exposure platform for rat was developed.•Stimulus responses were detected in cortex after IF-MF exposure to spinal cord.•The…”
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12
AIbZIP/CREB3L4 Promotes Cell Proliferation via the SKP2-p27 Axis in Luminal Androgen Receptor Subtype Triple-Negative Breast Cancer
Published in Molecular cancer research (02-04-2024)“…Breast cancer ranks first in incidence and fifth in cancer-related deaths among all types of cancer globally. Among breast cancer, triple-negative breast…”
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13
Joint optimization of segmentation and shape prior from level-set-based statistical shape model, and its application to the automated segmentation of abdominal organs
Published in Medical image analysis (01-02-2016)“…•Joint optimization of segmentation labeling and a shape prior defined by an SSM.•An optimal shape prior is found from the eigenshape space by branch-and-bound…”
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14
N‐glycosylation regulates MET processing and signaling
Published in Cancer science (01-04-2022)“…MET, the receptor for the hepatocyte growth factor (HGF), is strongly associated with resistance to tyrosine kinase inhibitors, key drugs that are used in the…”
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15
The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology
Published in Journal of biochemistry (Tokyo) (01-05-2011)“…Eukaryotic cells can adapt to endoplasmic reticulum (ER) dysfunction by producing diverse signals from the ER to the cytosol or nucleus. These signalling…”
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16
Analysis of the Mild strain of tomato yellow leaf curl virus, which overcomes Ty-2 gene–mediated resistance in tomato line H24
Published in Archives of virology (01-08-2016)“…In tomato line H24, an isolate of the Mild (Mld) strain of tomato yellow leaf curl virus (TYLCV-Mld [JR:Kis]) overcomes Ty-2 gene–mediated resistance and…”
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17
Signaling Over Distances
Published in Molecular & cellular proteomics (01-02-2016)“…Neurons are extremely polarized cells. Axon lengths often exceed the dimension of the neuronal cell body by several orders of magnitude. These extreme axonal…”
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Functional Outcome in Patients with Chronic Subdural Hematoma: Postoperative Delirium and Operative Procedure
Published in Neurologia Medico-Chirurgica (15-04-2022)“…Chronic subdural hematoma (CSDH) is a common neurosurgical condition and neurological condition improves after treatment in most patients. Recently more…”
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19
Automated measurement of bone scan index from a whole-body bone scintigram
Published in International journal for computer assisted radiology and surgery (01-03-2020)“…Purpose We propose a deep learning-based image interpretation system for skeleton segmentation and extraction of hot spots of bone metastatic lesion from a…”
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A 3D analysis of growth trajectory and integration during early human prenatal facial growth
Published in Scientific reports (25-03-2021)“…Significant shape changes in the human facial skeleton occur in the early prenatal period, and understanding this process is critical for studying a myriad of…”
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