Search Results - "SAIT, Sheila"

Myelodysplastic syndromes and autoimmune diseases—Case series and review of literature by Ustwani, Omar Al, Ford, Laurie A, Sait, Sheila J.N, Block, Anne Marie W, Barcos, Maurice, Vigil, Carlos E, Griffiths, Elizabeth A, Thompson, James E, Wang, Eunice S, Ambrus, Julian, Wetzler, Meir

“…Abstract Our objective was to recognize the association of autoimmune diseases (AD) in patients with myelodysplastic syndromes (MDS) and understand how this…”
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Ofatumumab plus HyperCVAD/HD‐MA induction leads to high rates of minimal residual disease negativity in patients with newly diagnosed mantle cell lymphoma: Results of a phase 2 study by Torka, Pallawi, Akhtar, Othman S., Reddy, Nishitha M., Baysal, Bora E., Kader, Angela, Groman, Adrienne, Nichols, Jenna, Mavis, Cory, Tario, Joseph D., Block, AnneMarie W., Sait, Sheila N. J., Ghione, Paola, Sundaram, Suchitra, Przespolewski, Eugene R., Mohr, Alice, Lund, Ian, Kostrewa, Jessica, McWhite, Kenneth, DeMarco, Joseph, Johnson, Michael, Darrall, Andrea, Thomas‐Talley, Rosh‐Neke, Wallace, Paul K., Neppalli, Vishala, Hutson, Alan, Hernandez‐Ilizaliturri, Francisco J.

“…Background Ofatumumab is a humanized type 1 anti‐CD20 monoclonal antibody. Preclinical studies show improved complement‐mediated cytotoxicity (CMC) compared to…”
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Low 25(OH) vitamin D3 levels are associated with adverse outcome in newly diagnosed, intensively treated adult acute myeloid leukemia by Lee, Hun Ju, Muindi, Josephia R., Tan, Wei, Hu, Qiang, Wang, Dan, Liu, Song, Wilding, Gregory E., Ford, Laurie A., Sait, Sheila N. J., Block, Annemarie W., Adjei, Araba A., Barcos, Maurice, Griffiths, Elizabeth A., Thompson, James E, Wang, Eunice S., Johnson, Candace S., Trump, Donald L., Wetzler, Meir

“…BACKGROUND Several studies have suggested that low 25(OH) vitamin D3 levels may be prognostic in some malignancies, but no studies have evaluated their impact…”
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Concomitant Venetoclax and Imatinib for Comanaging Chronic Lymphocytic Leukemia and Chronic Myeloid Leukemia: A Case Report by Przespolewski, Eugene R, Baron, Jeffrey, Kashef, Farshid, Fu, Kai, Jani Sait, Sheila N, Hernandez-Ilizaliturri, Francisco, Thompson, James

“…Patients with synchronous malignancies can be problematic to diagnose and manage because workup and therapeutic targeting for each individual malignancy must…”
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Inhibition of LSD1 in MDS progenitors restores differentiation of CD141Hi conventional dendritic cells by Srivastava, Pragya, Tzetzo, Stephanie L., Gomez, Eduardo Cortes, Eng, Kevin H., Jani Sait, Sheila N., Kuechle, Joseph B., Singh, Prashant K., De Jong, Kitty, Wiatrowski, Kyle R., Peresie, Jennifer, Dimitroff, Ava, Lynch, Miranda L., Wang, Jianmin, Abrams, Scott I., Griffiths, Elizabeth A., Nemeth, Michael J.

“…The use of immunotherapy to treat patients with myelodysplastic syndromes (MDS) shows promise but is limited by our incomplete understanding of the immunologic…”
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Hypoxia-inducible factor-1α protein expression is associated with poor survival in normal karyotype adult acute myeloid leukemia by Deeb, George, Vaughan, Mary M, McInnis, Ian, Ford, Laurie Ann, Sait, Sheila N.J, Starostik, Petr, Wetzler, Meir, Mashtare, Terry, Wang, Eunice S

“…Abstract We examined the predictive impact of HIF-1α protein expression on clinical outcome of 84 normal karyotype acute myeloid leukemia (NK-AML) patients…”
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Smoking adversely affects survival in acute myeloid leukemia patients by Varadarajan, Ramya, Licht, Andrea S., Hyland, Andrew J., Ford, Laurie A., Sait, Sheila N.J., Block, Annemarie W., Barcos, Maurice, Baer, Maria R., Wang, Eunice S., Wetzler, Meir

“…Smoking adversely affects hematopoietic stem cell transplantation outcome. We asked whether smoking affected outcome of newly diagnosed acute myeloid leukemia…”
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Is obesity a prognostic factor for acute myeloid leukemia outcome? by Lee, Hun Ju, Licht, Andrea S., Hyland, Andrew J., Ford, Laurie A., Sait, Sheila N. J., Block, AnneMarie W., Barcos, Maurice, Baer, Maria R., Wang, Eunice S., Wetzler, Meir

“…Obesity adversely affects outcome in pediatric acute lymphocytic leukemia and acute myeloid leukemia (AML). We asked if obesity, measured by body mass index…”
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Inhibition of LSD1 in Myelodysplastic Syndrome Progenitors Restores Differentiation of CD141Hi Conventional Dendritic Cells by Srivastava, Pragya, Tzetzo, Stephanie, Cortes Gomez, Eduardo, Eng, Kevin, Singh, Prashant K, De Jong, Kitty, Sait, Sheila N.J., Wiatrowski, Kyle, Lynch, Miranda L, Peresie, Jennifer, Wang, Jianmin, Griffiths, Elizabeth A., Nemeth, Michael J.

“…Background: Immunotherapeutic approaches for myelodysplastic syndrome (MDS) show promise, but progress is limited by our incomplete understanding of the…”
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Image cytometry‐based detection of aneuploidy by fluorescence in situ hybridization in suspension by Minderman, Hans, Humphrey, Kristen, Arcadi, Jane K., Wierzbicki, Andrzej, Maguire, Orla, Wang, Eunice S., Block, AnneMarie W., Sait, Sheila N. J., George, Thaddeus C., Wallace, Paul K.

“…Cytogenetic abnormalities are important diagnostic and prognostic criteria for hematologic malignancies. Karyotyping and fluorescence in situ hybridization…”
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Myeloid blastic transformation of myeloproliferative neoplasms—A review of 112 cases by Noor, Syed J, Tan, Wei, Wilding, Gregory E, Ford, Laurie A, Barcos, Maurice, Sait, Sheila N.J, Block, AnneMarie W, Thompson, James E, Wang, Eunice S, Wetzler, Meir

“…Abstract Blastic transformation of myeloproliferative neoplasms (MPN) is still poorly understood. We describe a cohort of 23 Roswell Park Cancer Institute…”
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Ofatumumab Plus Hypercvad/MA Induction Leads to High Rates of Minimal Residual Disease (MRD) Negativity in Patients with Newly Diagnosed Mantle Cell Lymphoma, Results of a Phase 2 Study by Torka, Pallawi, Reddy, Nishitha, Groman, Adrienne, Kader, Angela, Nichols, Jenna, Hutson, Alan, Mavis, Cory, Tario, Joseph Dennis, Wallace, Paul K., Block, AnneMarie W., Sait, Sheila N.J., Baysal, Bora E, Neppalli, Vishala T., Sundaram, Suchitra, Hernandez-Ilizaliturri, Francisco J.

“…Background: Minimal residual disease (MRD) status is an independent prognostic marker for response duration in patients with mantle cell lymphoma (MCL)…”
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Unusual B-Lymphoid Blastic Crisis as Initial Presentation of Chronic Myeloid Leukemia Imposes Diagnostic Challenges by Momen, Nouran, Baysal, Bora, Jani Sait, Sheila, Tario, Joseph, Qian, You-Wen

“…Chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disorder, characterized by reciprocal translocation t(9,22) (q34; q11), leading to increased…”
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Phase 1 study of arsenic trioxide, high‐dose cytarabine, and idarubicin to down‐regulate constitutive signal transducer and activator of transcription 3 activity in patients aged <60 years with acute myeloid leukemia by Wetzler, Meir, Andrews, Chris, Ford, Laurie A., Tighe, Sheila, Barcos, Maurice, Sait, Sheila N. J., Block, AnneMarie W., Nowak, Norma J., Baer, Maria R., Wang, Eunice S., Baumann, Heinz

“…BACKGROUND: Constitutive activation of signal transducer and activator of transcription‐3 (STAT3) was detected in blasts from approximately 50% of patients…”
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Treating octogenarian and nonagenarian acute myeloid leukemia patients—Predictive prognostic models by Harb, Antoine J., Tan, Wei, Wilding, Gregory E., Ford, LaurieAnn, Sait, Sheila N. J., Block, AnneMarie W., Barcos, Maurice, Wallace, Paul K., Wang, Eunice S., Wetzler, Meir

“…BACKGROUND: Treating the octogenarian and nonagenarian patients who have acute myeloid leukemia (AML) with intensive chemotherapy is controversial. Several…”
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CD19 expression in acute leukemia is not restricted to the cytogenetically aberrant populations by Francis, Jawad, Dharmadhikari, Avinash V., Sait, Sheila N. J., Deeb, George, Wallace, Paul K., Thompson, James E., Wang, Eunice S., Wetzler, Meir

“…Abstract Aberrant expression of the B lymphoid marker, CD19, in acute myeloid leukemia (AML) has frequently been associated with t(8;21)(q22;q22). However, AML…”
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Targeting 11q23 positive acute leukemia cells with high molecular weight-melanoma associated antigen-specific monoclonal antibodies by Drake, Allison S, Brady, Michael T, Wang, Xin Hui, Sait, Sheila J. N, Earp, Justin C, Ghoshal (Gupta), Sampa, Ferrone, Soldano, Wang, Eunice S, Wetzler, Meir

“…Background Acute leukemia with 11q23 aberrations is associated with a poor outcome with therapy. The lack of efficacy of conventional therapy has stimulated…”
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Abstract 3038: Investigating novel targeted therapies for double hit diffuse large B-cell lymphoma (DH-DLBCL) by Patel, Priyank P., Zeccola, Alison, Gu, Juan, Mavis, Cory, Sait, Sheila N. J., Neppalli, Vishala, Hernandez-Ilizaliturri, Francisco J.

“…Abstract Background: Molecular studies divide DLBCL into three subtypes with distinct pathogenesis and clinical outcomes: activated B-cell (ABC), germinal…”
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Down-regulation of signal transducer and activator of transcription 3 improves human acute myeloid leukemia-derived dendritic cell function by Brady, Michael T, Miller, Austin, Sait, Sheila N, Ford, Laurie A, Minderman, Hans, Wang, Eunice S, Lee, Kelvin P, Baumann, Heinz, Wetzler, Meir

“…Abstract Signal transducer and activator of transcription (STAT) 3 inhibits dendritic cell (DC) differentiation and is constitutively activated in blasts of…”
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Acute Myeloid Leukemia Secondary to Oxaliplatin Treatment for Esophageal Cancer by Damodaran, Senthilkumar, Bellavia, Tanya, Sait, Sheila N.J, Wang, Eunice S, Wetzler, Meir, Khushalani, Nikhil I

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