Search Results - "SAHARA, Naohi"

Phase II clinical trial of personalized VCD-VTD sequential therapy using the Vulnerable Elders Survey-13 (VES-13) for transplant-ineligible patients with newly diagnosed multiple myeloma by Nakazato, Tomonori, Hagihara, Masao, Sahara, Naohi, Tamai, Yotaro, Ishii, Ryuji, Tamaki, Shigehisa, Wake, Atsushi, Tajika, Kenji, Sakai, Rika, Kobayashi, Takeshi, Hua, Jian, Inoue, Morihiro, Aisa, Yoshinobu, Fujisawa, Shin, Miyazaki, Koji, Irie, Seiji, Tanaka, Eri, Higashihara, Masaaki

“…The Vulnerable Elders Survey-13 (VES-13) is a well-studied simplified frailty screening tool for elderly patients in the oncology setting. We conducted a…”
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Anti-inflammatory effects of ruxolitinib on chronic neutrophilic leukemia harboring CSF3R-T618I mutation with bilateral renal abscesses by Sahara, Naohi, Yokoyama, Kazuaki, Matsunaga, Takashi, Kitahara, Shinsuke, Fujii, Tomoki, Kobayashi, Seiichiro, Yusa, Nozomi, Shimizu, Eigo, Imoto, Seiya, Tojo, Arinobu, Ohno, Nobuhiro

“…Chronic neutrophilic leukemia (CNL) is a rare myeloproliferative neoplasm (MPN) characterized by sustained mature neutrophilic leukocytosis. Recently, presence…”
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Listeria meningitis during daratumumab/bortezomib/dexamethasone therapy in a patient with multiple myeloma by Fujii, Tomoki, Ohno, Nobuhiro, Kitahara, Shinsuke, Kobayashi, Seiichiro, Sahara, Naohi, Matsunaga, Takashi

“…An 88-year-old woman was diagnosed with multiple myeloma received third-line chemotherapy, including DBd (daratumumab [DARA], bortezomib, and dexamethasone…”
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Extranodal NK/T cell lymphoma, nasal type with local recurrence in the contralateral nasal cavity 15 years after initial sequential chemoradiotherapy by Fujii, Tomoki, Ohno, Nobuhiro, Kitahara, Shinsuke, Kobayashi, Seiichiro, Sahara, Naohi, Sakamoto, Nami, Arahira, Satoko, Matsunaga, Takashi

“…A 72-year-old woman was diagnosed with extranodal NK/T cell lymphoma of the right nasal cavity and received sequential radiochemotherapy comprising focal…”
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Collision tumor of primary malignant lymphoma and adenocarcinoma in the colon: Report of a case by Sasaki, Shin, Hatanaka, Kazuhito, Sahara, Naohi, Uekusa, Toshimasa, Hirayama, Kaho, Shirahata, Atsushi, Ishimaru, Masahiro

“…This report presents the case of a 62-year-old man with a collision tumor of primary malignant lymphoma and adenocarcinoma in the cecum. All regional…”
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Clinicopathological and prognostic characteristics of CD56‐negative multiple myeloma by Sahara, Naohi, Takeshita, Akihiro, Shigeno, Kazuyuki, Fujisawa, Shinya, Takeshita, Kaori, Naito, Kensuke, Ihara, Michio, Ono, Takaaki, Tamashima, Sadahiro, Nara, Kenji, Ohnishi, Kazunori, Ohno, Ryuzo

“…We analysed CD56 expression in 70 patients with multiple myeloma (MM) to determine its clinicopathological and prognostic significance. Fifty‐five (79%)…”
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A Patient Surviving More Than Five Years Due to the Effect of Sequential Alternating Chemotherapy Administered to Metachronous Overlapping Cancer of Multiple Myeloma and StageⅣ EGFR Positive Non-Small Cell Lung Cancer by Fujii, Tomoki, Ohno, Nobuhiro, Matsui, Tomoharu, Kitahara, Shinsuke, Matsunaga, Takashi, Sahara, Naohi, Doi, Ayako, Kurosaki, Yuicihiro, Inoue, Hisako, Kobayash, Seiichiro

“…A woman in her late 50s visited our department because an abnormal shadow of her right lung was seen on her chest radiographs. She was diagnosed with Stage ⅠA…”
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Arsenic trioxide therapy in relapsed or refractory Japanese patients with acute promyelocytic leukemia : Updated outcomes of the phase II study and postremission therapies by SHIGENO, Kazuyuki, NAITO, Kensuke, SAHARA, Naohi, KOBAYASHI, Miki, NAKAMURA, Satoki, FUJISAWA, Sinya, SHINJO, Kaori, TAKESHITA, Akihiro, OHNO, Ryuzo, OHNISHI, Kazunori

“…Recently, arsenic trioxide (ATO) has been proved to induce complete remission (CR) at a high rate in patients with acute promyelocytic leukemia (APL). We…”
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Prognostic Significance of Surface Markers Expressed in Multiple Myeloma: CD56 and Other Antigens by SAHARA, NAOHI, TAKESHITA, AKIHIRO

“…Multiple myeloma (MM) is characterized by increased numbers of malignant plasma cells. Plasma cells, that represent the terminal differentiation of B…”
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Two cases of acute promyelocytic leukemia complicated by torsade de pointes during arsenic trioxide therapy by NAITO, Kensuke, KOBAYASHI, Miki, SAHARA, Naohi, SHIGENO, Kazuyuki, NAKAMURA, Satoki, SHINJO, Kaori, TOBITA, Tadasu, TAKESHITA, Akihiro, OHNO, Ryuzo, OHNISHI, Kazunori

“…We describe 2 patients with acute promyelocytic leukemia (APL) in whom torsade de pointes (TdP) developed during treatment with arsenic trioxide. Patient 1 was…”
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Etodolac induces apoptosis and inhibits cell adhesion to bone marrow stromal cells in human myeloma cells by Nakamura, Satoki, Kobayashi, Miki, Shibata, Kiyoshi, Sahara, Naohi, Shigeno, Kazuyuki, Shinjo, Kaori, Naito, Kensuke, Hayashi, Hideharu, Ohnishi, Kazunori

“…Cyclooxygenase-2 (COX-2) is reported to regulate apoptosis and to be an important cellular target for therapy. We examined whether etodolac, meloxicam, and…”
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Delayed Recovery of Normal Hematopoiesis in Arsenic Trioxide Treatment of Acute Promyelocytic Leukemia: A Comparison to All-trans Retinoic Acid Treatment by SHINJO, Kaori, TAKESHITA, Akihiro, SAHARA, Naohi, KOBAYASHI, Miki, NAKAMURA, Satoki, SHIGENO, Kazuyuki, NAITO, Kensuke, MAEKAWA, Masato, OHNISHI, Kazunori, OHNO, Ryuzo

“…Objective To examine laboratory data including total blood cell count, leukocyte morphology and coagulation parameters during treatment for acute promyelocytic…”
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Two patients with all-trans retinoic acid-resistant acute promyelocytic leukemia treated successfully with gemtuzumab ozogamicin as a single agent by TAKESHITA, Akihiro, SHINJO, Kaori, YADA, Yoshihiro, TESHIMA, Hirofumi, TAKEUCHI, Jin, OHNISHI, Kazunori, OHNO, Ryuzo, NAITO, Kensuke, MATSUI, Hirotaka, SAHARA, Naohi, SHIGENO, Kazuyuki, SUZUMURA, Taeko, HORII, Toshinobu, SHIRAI, Naohito, MAEKAWA, Masato

“…Acute promyelocytic leukemia (APL) cells express a considerable level of CD33, which is the target of gemtuzumab ozogamicin (GO), and a significantly lower…”
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Daratumumab-resistant multiple myeloma with extramedullar disease successfully treated with combination elotuzumab, pomalidomide and dexamethasone: A case report by Sakashita, Masataka, Sahara, Naohi, Aoki, Jun, Matsunaga, Takashi, Kobayashi, Seiichiro, Kitahara, Shinsuke, Fujii, Tomoki, Ohno, Nobuhiro

“…Despite the emergence of monoclonal antibodies, the prognosis of patients with multiple myeloma (MM) with extramedullary disease remains poor. The present…”
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Daratumumab‑resistant multiple myeloma with extramedullary disease successfully treated with combination elotuzumab, pomalidomide and dexamethasone: A case report by Sakashita, Masataka, Sahara, Naohi, Aoki, Jun, Matsunaga, Takashi, Kobayashi, Seiichiro, Kitahara, Shinsuke, Fujii, Tomoki, Ohno, Nobuhiro

“…Despite the emergence of monoclonal antibodies, the prognosis of patients with multiple myeloma (MM) with extramedullary disease remains poor. The present…”
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Phase II Clinical Trial of Personalized-VCD-VTD Sequential Therapy Using VES-13 for Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma by Nakazato, Tomonori, Hagihara, Masao, Irie, Seiji, Sahara, Naohi, Tanaka, Eri, Tamai, Yotaro, Ishii, Ryuji, Tamaki, Shigehisa, Wake, Atsushi, Tajika, Kenji, Sakai, Rika, Kobayashi, Takeshi, Sano, Fumiya, Abe, Takayuki, Roberts, Rachel, Fujisawa, Shin, Miyazaki, Koji, Higashihara, Masaaki

“…Background Most patients with newly diagnosed multiple myeloma (MM) are aged > 65 years with 30% aged > 75 years. Many elderly patients are frail because of…”
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Pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia treated with arsenic trioxide by FUJISAWA, Shinya, OHNO, Ryuzo, HASHIMOTO, Hisakuni, KINOSHITA, Kenji, SHIMOYA, Masahito, KAISE, Toshikazu, OHNISHI, Kazunori, SHIGENO, Kazuyuki, SAHARA, Naohi, NAKAMURA, Satoki, NAITO, Kensuke, KOBAYASHI, Miki, SHINJO, Kaori, TAKESHITA, Akihiro, SUZUKI, Yoshinari

“…To investigate the pharmacokinetics of arsenic species in Japanese patients with relapsed or refractory acute promyelocytic leukemia (APL) treated with arsenic…”
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Bcr-Abl Inhibitors Induce Expression of HoxA10, Playing a Role as an Inhibitor of the Proliferation through PI3K/PKB Pathway in Chronic Myelogenous Leukemia Cells by Sugimoto, Yuya, Nakamura, Satoki, Ono, Takaaki, Kobayashi, Miki, Sahara, Naohi, Shinjo, Kaori, Shigeno, Kazuyuki, Ohnishi, Kazunori

“…[Background] Homeobox (Hox) genes are grouped together in 4 clusters, A to D. Recent studies has shown that the Hox proteins are important in the control of…”
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Analysis of Aurora Kinase Expressions and Cell Cycle Regulation by Aurora-C in Leukemia Cells by Kobayashi, Miki, Nakamura, Satoki, Ono, Takaaki, Sugimoto, Yuya, Sahara, Naohi, Shinjo, Kaori, Shigeno, Kazuyuki, Ohnishi, Kazunori

“…Background: The conserved Aurora family kinases, a family of mitotic serine/threonine kinases, have three members (Aurora-A, -B and -C) in mammalian cells. The…”
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Hereditary spherocytosis associated with severe hypophosphatemia in patients recovering from aplastic crisis by Sahara, N, Tamashima, S, Ihara, M

“…This is a report about two cases of hereditary spherocytosis complicated by severe hypophosphatemia, while recovering from aplastic crisis. Case #1: A…”
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