Search Results - "SAHAKIAN, B. J"

Knowing me, knowing you: theory of mind in AI by Cuzzolin, F, Morelli, A, Cîrstea, B, Sahakian, B J

“…Artificial intelligence has dramatically changed the world as we know it, but is yet to fully embrace 'hot' cognition, i.e., the way an intelligent being's…”
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Disorders of compulsivity: a common bias towards learning habits by Voon, V, Derbyshire, K, Rück, C, Irvine, M A, Worbe, Y, Enander, J, Schreiber, L R N, Gillan, C, Fineberg, N A, Sahakian, B J, Robbins, T W, Harrison, N A, Wood, J, Daw, N D, Dayan, P, Grant, J E, Bullmore, E T

“…Why do we repeat choices that we know are bad for us? Decision making is characterized by the parallel engagement of two distinct systems, goal-directed and…”
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Cognition as a treatment target in depression by Kaser, M, Zaman, R, Sahakian, B J

“…Cognitive dysfunction in depression is associated with poorer clinical outcomes and impaired psychosocial functioning. However, most treatments for depression…”
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Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making by Clark, L., Bechara, A., Damasio, H., Aitken, M. R. F., Sahakian, B. J., Robbins, T. W.

“…The ventromedial prefrontal cortex (vmPFC) and insular cortex are implicated in distributed neural circuitry that supports emotional decision-making. Previous…”
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Temporal discounting in major depressive disorder by Pulcu, E, Trotter, P D, Thomas, E J, McFarquhar, M, Juhasz, G, Sahakian, B J, Deakin, J F W, Zahn, R, Anderson, I M, Elliott, R

“…Major depressive disorder (MDD) is associated with abnormalities in financial reward processing. Previous research suggests that patients with MDD show reduced…”
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Emotion modulates cognitive flexibility in patients with major depression by Murphy, F C, Michael, A, Sahakian, B J

“…Depression is associated with alterations of emotional and cognitive processing, and executive control in particular. Previous research has shown that…”
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Cognitive reserve in neuropsychiatry by Barnett, J H, Salmond, C H, Jones, P B, Sahakian, B J

“…The idea that superior cognitive function acts as a protective factor against dementia and the consequences of head injury is well established. Here we suggest…”
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Default mode network connectivity during task execution by Vatansever, D., Menon, D.K., Manktelow, A.E., Sahakian, B.J., Stamatakis, E.A.

“…Initially described as task-induced deactivations during goal-directed paradigms of high attentional load, the unresolved functionality of default mode regions…”
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Angular default mode network connectivity across working memory load by Vatansever, D, Manktelow, A E, Sahakian, B J, Menon, D K, Stamatakis, E A

“…Initially identified during no-task, baseline conditions, it has now been suggested that the default mode network (DMN) engages during a variety of working…”
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The neuropsychology of obsessive compulsive disorder: the importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers by Chamberlain, S.R., Blackwell, A.D., Fineberg, N.A., Robbins, T.W., Sahakian, B.J.

“…Obsessive compulsive disorder (OCD) is a highly debilitating neuropsychiatric condition with estimated lifetime prevalence of 2–3%, more than twice that of…”
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Recurrence in major depressive disorder: a neurocognitive perspective by Robinson, O J, Sahakian, B J

“…Depressive disorders are amongst the leading causes of disability and mortality worldwide and, as such, it is predicted that by 2010 only cardio-ischaemic…”
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Approach and avoidance learning in patients with major depression and healthy controls: relation to anhedonia by Chase, H W, Frank, M J, Michael, A, Bullmore, E T, Sahakian, B J, Robbins, T W

“…Central to understanding of the behavioural consequences of depression has been the theory that the disorder is accompanied by an increased sensitivity to…”
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Social-economical decision making in current and remitted major depression by Pulcu, E, Thomas, E J, Trotter, P D, McFarquhar, M, Juhasz, G, Sahakian, B J, Deakin, J F W, Anderson, I M, Zahn, R, Elliott, R

“…Prosocial emotions related to self-blame are important in guiding human altruistic decisions. These emotions are elevated in major depressive disorder (MDD),…”
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Stop signal response inhibition is not modulated by tryptophan depletion or the serotonin transporter polymorphism in healthy volunteers : implications for the 5-HT theory of impulsivity by CLARK, L, ROISER, J. P, COOLS, R, RUBINSZTEIN, D. C, SAHAKIAN, B. J, ROBBINS, T. W

“…Reduced serotonin neurotransmission is implicated in disorders of impulse control, but the involvement of serotonin in inhibitory processes in healthy human…”
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Inhibition of thoughts and actions in obsessive-compulsive disorder: extending the endophenotype? by Morein-Zamir, S, Fineberg, N A, Robbins, T W, Sahakian, B J

“…Obsessive-compulsive disorder (OCD) has been associated with impairments in stop-signal inhibition, a measure of motor response suppression. The study used a…”
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Altered functional connectivity in the motor network after traumatic brain injury by KASAHARA, M, MENON, D. K, SALMOND, C. H, OUTTRIM, J. G, TAYLOR TAVARES, J. V, CARPENTER, T. A, PICKARD, J. D, SAHAKIAN, B. J, STAMATAKIS, E. A

“…A large proportion of survivors of traumatic brain injury (TBI) have persistent cognitive impairments, the profile of which does not always correspond to the…”
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Differing patterns of temporal atrophy in Alzheimer's disease and semantic dementia by GALTON, C. J, PATTERSON, K, GRAHAM, K, LAMBON-RALPH, M. A, WILLIAMS, G, ANTOUN, N, SAHAKIAN, B. J, HODGES, J. R

“…To characterize and quantify the patterns of temporal lobe atrophy in AD vs semantic dementia and to relate the findings to the cognitive profiles. Medial…”
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Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals by Ersche, K D, Fletcher, P C, Lewis, S J G, Clark, L, Stocks-Gee, G, London, M, Deakin, J B, Robbins, T W, Sahakian, B J

“…There is converging evidence for impairments in decision-making in chronic substance users. In the light of findings that substance abuse is associated with…”
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Paroxetine does not improve symptoms and impairs cognition in frontotemporal dementia: a double-blind randomized controlled trial by DEAKIN, J. B, RAHMAN, S, NESTOR, P. J, HODGES, J. R, SAHAKIAN, B. J

“…Patients with frontal variant frontotemporal dementia (fvFTD) present with disinhibition, impulsiveness, apathy, altered appetite and stereotypic behaviors. A…”
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Neuropsychological impairment in patients with major depressive disorder: the effects of feedback on task performance by Murphy, F C, Michael, A, Robbins, T W, Sahakian, B J

“…Recent evidence suggests that an abnormal response to performance feedback may contribute to the wide-ranging neuropsychological deficits typically associated…”
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