Search Results - "SAGEBIEL, Richard W"
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Discordance in the histopathologic diagnosis of melanoma at a melanoma referral center
Published in Journal of the American Academy of Dermatology (01-05-2010)“…Background Histopathologic analysis remains the gold standard for the pathologic diagnosis of melanoma. Numerous histologic criteria are used to diagnose…”
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Analysis of sentinel lymph node positivity in patients with thin primary melanoma
Published in Journal of the American Academy of Dermatology (01-04-2013)“…Background A minority of patients with T1 melanoma will have a positive sentinel lymph node (SLN) biopsy (SLNB) finding. Identifying who will develop…”
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The Gene Expression Signatures of Melanoma Progression
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2005)“…Because of the paucity of available tissue, little information has previously been available regarding the gene expression profiles of primary melanomas. To…”
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multi-marker assay to distinguish malignant melanomas from benign nevi
Published in Proceedings of the National Academy of Sciences - PNAS (14-04-2009)“…The histopathological diagnosis of melanoma can be challenging. No currently used molecular markers accurately distinguish between nevus and melanoma. Recent…”
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A Multimarker Prognostic Assay for Primary Cutaneous Melanoma
Published in Clinical cancer research (15-11-2009)“…Purpose: To determine the prognostic significance of a multimarker assay incorporating expression levels of three molecular markers in primary cutaneous…”
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Identifying Individuals at High Risk of Melanoma: A Practical Predictor of Absolute Risk
Published in Journal of clinical oncology (01-08-2006)“…We developed a model to estimate the 5-year absolute risk of melanoma to efficiently identify individuals at increased risk of melanoma for potential…”
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Genes and Pathways Downstream of Telomerase in Melanoma metastasis
Published in Proceedings of the National Academy of Sciences - PNAS (25-07-2006)“…Recent studies have demonstrated a role for telomerase in driving tumor progression, but its mechanism of action remains unclear. Here we show that stable,…”
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Pleckstrin homology domain-interacting protein (PHIP) as a marker and mediator of melanoma metastasis
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-2012)“…Although melanomas with mutant v-Raf murine sarcoma viral oncogene homolog B1 (BRAF) can now be effectively targeted, there is no molecular target for most…”
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Diet and Melanoma in a Case-Control Study
Published in Cancer epidemiology, biomarkers & prevention (01-06-2004)“…Background: Malignant melanoma has been one of the most rapidly increasing cancers within the United States with few modifiable risk factors. This study…”
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A patient-centered methodology that improves the accuracy of prognostic predictions in cancer
Published in PloS one (27-02-2013)“…Individualized approaches to prognosis are crucial to effective management of cancer patients. We developed a methodology to assign individualized 5-year…”
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Correction: A Patient-Centered Methodology That Improves the Accuracy of Prognostic Predictions in Cancer
Published in PloS one (21-10-2013)Get full text
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Tumor Vascularity in the Prognostic Assessment of Primary Cutaneous Melanoma
Published in Journal of clinical oncology (01-04-2002)“…The vascular supply of the primary tumor is recognized to play an important role in the progression of a number of solid tumors. However, the role of tumor…”
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Prognostic Significance of Nuclear Receptor Coactivator-3 Overexpression in Primary Cutaneous Melanoma
Published in Journal of clinical oncology (01-10-2006)“…To assess the prognostic significance of nuclear receptor coactivator-3 (NCOA3) overexpression in primary cutaneous melanoma. NCOA3 expression was assessed…”
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14
NF-κB in the Vascular Progression of Melanoma
Published in Journal of clinical oncology (15-02-2004)“…To examine a model of melanoma progression based on vascular factors and the role of NF-kappa B in the vascular progression of melanoma. A data set of 526…”
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The role of BPTF in melanoma progression and in response to BRAF-targeted therapy
Published in JNCI : Journal of the National Cancer Institute (01-05-2015)“…Bromodomain PHD finger transcription factor (BPTF) plays an important role in chromatin remodeling, but its functional role in tumor progression is…”
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Prospective Validation of Molecular Prognostic Markers in Cutaneous Melanoma: A Correlative Analysis of E1690
Published in Clinical cancer research (15-11-2017)“…To validate the prognostic impact of combined expression levels of three markers (SPP1, RGS1, and NCOA3) in melanoma specimens from patients enrolled in the…”
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BPTF transduces MITF-driven prosurvival signals in melanoma cells
Published in Proceedings of the National Academy of Sciences - PNAS (31-05-2016)“…Microphthalmia-associated transcription factor (MITF) plays a critical and complex role in melanocyte transformation. Although several downstream targets of…”
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Osteopontin as a molecular prognostic marker for melanoma
Published in Cancer (01-01-2008)“…BACKGROUND. Osteopontin has been suggested as a marker of disease progression in patients with melanoma because of its overexpression in recent microarray…”
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Novel Role for RGS1 in Melanoma Progression
Published in The American journal of surgical pathology (01-08-2008)“…RGS1 (regulator of G protein signaling 1) encodes a member of the regulator of G protein family. Recently, RGS1 was found to be overexpressed in gene…”
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Prognostic Impact of PHIP Copy Number in Melanoma: Linkage to Ulceration
Published in Journal of investigative dermatology (01-03-2014)“…Ulceration is an important prognostic factor in melanoma whose biologic basis is poorly understood. Here we assessed the prognostic impact of pleckstrin…”
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