Search Results - "SAFAK, Mahmut"

A Comprehensive Proteomics Analysis of the JC Virus (JCV) Large and Small Tumor Antigen Interacting Proteins: Large T Primarily Targets the Host Protein Complexes with V-ATPase and Ubiquitin Ligase Activities While Small t Mostly Associates with Those Having Phosphatase and Chromatin-Remodeling Functions by Saribas, Sami, Safak, Mahmut

“…The oncogenic potential of both the polyomavirus large (LT-Ag) and small (Sm t-Ag) tumor antigens has been previously demonstrated in both tissue culture and…”
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Regulation of Gene Expression in Primate Polyomaviruses by WHITE, Martyn K, SAFAK, Mahmut, KHALILI, Kamel

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Discovery and characterization of novel trans‐spliced products of human polyoma JC virus late transcripts from PML patients by Saribas, A. Sami, DeVoto, Julia, Golla, Akhil, Wollebo, Hassen S., White, Martyn K., Safak, Mahmut

“…Although the human neurotropic polyomavirus, JC virus (JCV), was isolated almost a half century ago, understanding the molecular mechanisms governing its…”
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Small tumor antigen of polyomaviruses: Role in viral life cycle and cell transformation by Khalili, Kamel, Sariyer, Ilker Kudret, Safak, Mahmut

“…The regulatory proteins of polyomaviruses, including small and large T antigens, play important roles, not only in the viral life cycle but also in…”
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Role for tumor necrosis factor-alpha in JC virus reactivation and progressive multifocal leukoencephalopathy by Wollebo, Hassen S, Safak, Mahmut, Del Valle, Luis, Khalili, Kamel, White, Martyn K

“…Abstract JCV causes the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML). After primary infection, JCV persists in a latent state,…”
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Integrin α9β1 is a receptor for nerve growth factor and other neurotrophins by Staniszewska, Izabela, Sariyer, Ilker K., Lecht, Shimon, Brown, Meghan C., Walsh, Erin M., Tuszynski, George P., Safak, Mahmut, Lazarovici, Philip, Marcinkiewicz, Cezary

“…The integrin α9β1 is a multifunctional receptor that interacts with a variety of ligands including vascular cell adhesion molecule 1, tenascin C and…”
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Infection by agnoprotein-negative mutants of polyomavirus JC and SV40 results in the release of virions that are mostly deficient in DNA content by Sariyer, Ilker K, Saribas, Abdullah S, White, Martyn K, Safak, Mahmut

“…Human polyomavirus JC (JCV) is the etiologic agent of a brain disease, known as progressive multifocal leukoencephalopathy (PML). The JCV genome encodes a…”
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The agnoprotein of polyomaviruses: A multifunctional auxiliary protein by Khalili, Kamel, White, Martyn K., Sawa, Hirofumi, Nagashima, Kazuo, Safak, Mahmut

“…The late region of the three primate polyomaviruses (JCV, BKV, and SV40) encodes a small, highly basic protein known as agnoprotein. While much attention…”
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Evidence for dysregulation of cell cycle by human polyomavirus, JCV, late auxiliary protein by DARBINYAN, Armine, DARBINIAN, Nune, SAFAK, Mahmut, RADHAKRISHNAN, Sujatha, GIORDANO, Antonio, KHALILI, Kamel

“…The late region of the human neurotropic JC virus encodes a 71 amino acid protein, named Agnoprotein, whose biological function remains elusive. Here we…”
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Phosphorylation Mutants of JC Virus Agnoprotein Are Unable To Sustain the Viral Infection Cycle by SARIYER, Ilker K, AKAN, Ilhan, PALERMO, Victoria, GORDON, Jennifer, KHALILI, Kamel, SAFAK, Mahmut

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Cdk9 phosphorylates p53 on serine 392 independently of CKII by Claudio, Pier Paolo, Cui, Jianqi, Ghafouri, Mohammad, Mariano, Chiara, White, Martyn K., Safak, Mahmut, Sheffield, Joel B., Giordano, Antonio, Khalili, Kamel, Amini, Shohreh, Sawaya, Bassel E.

“…The tumor suppressor p53 is an important cellular protein, which controls cell cycle progression. Phosphorylation is one of the mechanisms by which p53 is…”
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Functional Interaction between JC Virus Late Regulatory Agnoprotein and Cellular Y-Box Binding Transcription Factor, YB-1 by Safak, Mahmut, Sadowska, Beata, Barrucco, Robert, Khalili, Kamel

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Interaction of JC Virus Agno Protein with T Antigen Modulates Transcription and Replication of the Viral Genome in Glial Cells by Safak, M, Barrucco, R, Darbinyan, A, Okada, Y, Nagashima, K, Khalili, K

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Regulation of Human Polyomavirus JC Virus Gene Transcription by AP-1 in Glial Cells by Sadowska, Beata, Barrucco, Robert, Khalili, Kamel, Safak, Mahmut

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Generation and characterization of JCV permissive hybrid cell lines by Sariyer, Ilker K., Safak, Mahmut, Gordon, Jennifer, Khalili, Kamel

“…JC virus (JCV) is a human neurotropic polyomavirus whose replication in the central nervous system induces the fatal demyelinating disease, progressive…”
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Members of the AP-1 Family, c-Jun and c-Fos, Functionally Interact with JC Virus Early Regulatory Protein Large T Antigen by Kim, Joanne, Woolridge, Stefanie, Biffi, Renato, Borghi, Elisa, Lassak, Adam, Ferrante, Pasquale, Amini, Shohreh, Khalili, Kamel, Safak, Mahmut

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Physical and Functional Interaction between the Y-Box Binding Protein YB-1 and Human Polyomavirus JC Virus Large T Antigen by Safak, M, Gallia, G L, Ansari, S A, Khalili, K

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Expression of novel proteins by polyomaviruses and recent advances in the structural and functional features of agnoprotein of JC virus, BK virus, and simian virus 40 by Saribas, A. Sami, Coric, Pascale, Bouaziz, Serge, Safak, Mahmut

“…Polyomavirus family consists of a highly diverse group of small DNA viruses. The founding family member (MPyV) was first discovered in the newborn mouse in the…”
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A comprehensive proteomics analysis of JC virus Agnoprotein-interacting proteins: Agnoprotein primarily targets the host proteins with coiled-coil motifs by Saribas, A. Sami, Datta, Prasun K., Safak, Mahmut

“…JC virus (JCV) Agnoprotein (Agno) plays critical roles in successful completion of the viral replication cycle. Understanding its regulatory roles requires a…”
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Human neurotropic polyomavirus, JC virus, agnoprotein targets mitochondrion and modulates its functions by Saxena, Reshu, Saribas, Sami, Jadiya, Pooja, Tomar, Dhanendra, Kaminski, Rafal, Elrod, John W., Safak, Mahmut

“…JC virus encodes an important regulatory protein, known as Agnoprotein (Agno). We have recently reported Agno's first protein-interactome with its cellular…”
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