Search Results - "SADEGHIZADEH, Majid"
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Design and fabrication of dual responsive lignin-based nanogel via “grafting from” atom transfer radical polymerization for curcumin loading and release
Published in Scientific reports (21-01-2021)“…The story of human dreams about curing all diseases, disorders and lesions is as old as human history. In the frontier of medical science, nanomedicine is…”
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Mir-183 functions as an oncogene via decreasing PTEN in breast cancer cells
Published in Scientific reports (19-05-2023)“…Regarding the important role of microRNAs in breast cancer, investigating the molecular mechanisms of miRs and their impacts on breast cancer progression is…”
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Polymerized nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative processes and enhancing neuroprotection and myelin repair
Published in Neuropharmacology (01-12-2015)“…Multiple Sclerosis (MS) is an inflammatory demyelinating disorder of central nervous system (CNS). Polyphenol curcumin has been used in traditional medicine as…”
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microRNA-141-3p-containing small extracellular vesicles derived from epithelial ovarian cancer cells promote endothelial cell angiogenesis through activating the JAK/STAT3 and NF-κB signaling pathways
Published in Journal of cell communication and signaling (01-06-2020)“…Paracrine signaling between tumor and surrounding stromal cells is critical for the maintenance of tumor microenvironment during ovarian cancer progression…”
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Dendrosomal curcumin increases expression of the long non-coding RNA gene MEG3 via up-regulation of epi-miRs in hepatocellular cancer
Published in Phytomedicine (Stuttgart) (15-09-2015)“…Hepatocellular carcinoma is the fifth most common cancer worldwide, with poor prognosis and resistance to chemotherapy. This gives novel cancer treatment…”
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6
Combination treatment of dendrosomal nanocurcumin and low-level laser therapy develops proliferation and migration of mouse embryonic fibroblasts and alter TGF-β, VEGF, TNF-α and IL-6 expressions involved in wound healing process
Published in PloS one (06-05-2021)“…Pressure ulcer (PU) is known as the third most costly disorder usually caused by prolonged pressure and stagnation in various parts of the body. Although…”
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Down-regulation of lncRNA, GAS5 decreases chemotherapeutic effect of dendrosomal curcumin (DNC) in breast cancer cells
Published in Phytomedicine (Stuttgart) (15-03-2018)“…Despite positive results obtained from anticancer activities of curcumin, there are some obstacles that limit its use as an anticancer agent. Different methods…”
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MicroRNA-203a inhibits breast cancer progression through the PI3K/Akt and Wnt pathways
Published in Scientific reports (27-02-2024)“…MicroRNA expression in breast cancer (BC) is explored both as a potential biomarker and for therapeutic purposes. Recent studies have revealed that miR-203a-3p…”
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Up-regulation of HOTAIR long non-coding RNA in human gastric adenocarcinoma tissues
Published in Medical oncology (Northwood, London, England) (01-09-2013)“…HOTAIR is a known long non-coding RNA which has recently been associated with the progression of some cancer types. It has been reported that HOTAIR expression…”
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Cancer-associated fibroblasts enhance cell proliferation and metastasis of colorectal cancer SW480 cells by provoking long noncoding RNA UCA1
Published in Journal of cell communication and signaling (01-03-2019)“…Cancer-associated fibroblasts (CAFs) have been considered as major players in tumor growth and malignancy. In colorectal cancer (CRC), CAFs are attendance in…”
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Bacteriophages and their applications in the diagnosis and treatment of hepatitis B virus infection
Published in World journal of gastroenterology : WJG (07-09-2014)“…Hepatitis B virus(HBV) infection is a major global health challenge leading to serious disorders such as cirrhosis and hepatocellular carcinoma. Currently,…”
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Intra-abdominal transplantation of PLGA/PCL/M13 phage electrospun scaffold induces self-assembly of lymphoid tissue-like structure
Published in Biomedicine & pharmacotherapy (01-04-2024)“…Lymphoid organs are the main structural components of the immune system. In the current research, the mixture of poly lactic-co-glycolic acid (PLGA),…”
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CML derived exosomes promote tumor favorable functional performance in T cells
Published in BMC cancer (07-09-2021)“…Background Leukemic cells facilitate the creation of the tumor-favorable microenvironment in the bone marrow niche using their secreted factors. There are not…”
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Mild hyperthermia induced by gold nanorods acts as a dual-edge blade in the fate of SH-SY5Y cells via autophagy
Published in Scientific reports (14-12-2021)“…Unraveling unwanted side effects of nanotechnology-based therapies like photothermal therapy (PTT) is vital in translational nanomedicine. Herein, we monitored…”
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Monocytes educated by cancer-associated fibroblasts secrete exosomal miR-181a to activate AKT signaling in breast cancer cells
Published in Journal of translational medicine (03-12-2022)“…Cancer-associated fibroblasts (CAFs), one of the major components of the tumor stroma, contribute to an immunosuppressive tumor microenvironment (TME) through…”
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Development of an ostrich-derived single-chain variable fragment (scFv) against PTPRN extracellular domain
Published in Scientific reports (14-02-2024)“…In type 1 diabetes, the immune system destroys pancreatic beta cells in an autoimmune condition. To overcome this disease, a specific monoclonal antibody that…”
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Synthesis and Characterization of a Nano-Polyplex system of GNRs-PDMAEA-pDNA: An Inert Self-Catalyzed Degradable Carrier for Facile Gene Delivery
Published in Scientific reports (25-05-2018)“…Engineering molecules at nano-scale is a promising approach in targeting and curing diseases. In this research, fabricated new hybrid system called…”
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A biosynthetic nerve guide conduit based on silk/SWNT/fibronectin nanocomposite for peripheral nerve regeneration
Published in PloS one (30-09-2013)“…As a contribution to the functionality of nerve guide conduits (NGCs) in nerve tissue engineering, here we report a conduit processing technique through…”
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Stimuli-Responsive, Plasmonic Nanogel for Dual Delivery of Curcumin and Photothermal Therapy for Cancer Treatment
Published in Frontiers in chemistry (20-01-2021)“…Nanogels (Ng) are crosslinked polymer-based hydrogel nanoparticles considered to be next-generation drug delivery systems due to their superior properties,…”
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Attempts to Overcome Remyelination Failure: Toward Opening New Therapeutic Avenues for Multiple Sclerosis
Published in Cellular and molecular neurobiology (01-11-2017)“…Multiple sclerosis (MS) is a chronic immune-mediated disorder of the central nervous system that results in destruction of the myelin sheath wrapped around the…”
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