Search Results - "SADEGHI, Kambis"

Vitamin D3 down‐regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen‐associated molecular patterns by Sadeghi, Kambis, Wessner, Barbara, Laggner, Ute, Ploder, Martin, Tamandl, Dietmar, Friedl, Josef, Zügel, Ullrich, Steinmeyer, Andreas, Pollak, Arnold, Roth, Erich, Boltz‐Nitulescu, George, Spittler, Andreas

“…Toll‐like receptors (TLR) represent an ancient front‐line defence system that enables the host organism to sense the presence of microbial components within…”
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The novel polyclonal Ab preparation trimodulin attenuates ex vivo endotoxin-induced immune reactions in early hyperinflammation by Duerr, Celia, Bacher, Annica, de Martin, Angelika, Sachet, Monika, Sadeghi, Kambis, Baumann, Suzann, Heinz, Corina, Spittler, Andreas

“…Sepsis is a syndrome associated with excessive inflammation. Since mortality from sepsis remains high, more laboratory research is needed to provide insight…”
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GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes by Sadeghi, Kambis, Wisgrill, Lukas, Wessely, Isabelle, Diesner, Susanne C, Schüller, Simone, Dürr, Celia, Heinle, Armando, Sachet, Monika, Pollak, Arnold, Förster-Waldl, Elisabeth, Spittler, Andreas

“…Toll-like receptors (TLR) are crucial sensors of microbial agents such as bacterial or viral compounds. These receptors constitute key players in the induction…”
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Necessity of early and continuous monitoring for possible infectious complications in children undergoing therapeutic hypothermia by Brandt, Jennifer B., Steiner, Sabine, Schlager, Gerald, Sadeghi, Kambis, Vargha, Regina, Golej, Johann, Hermon, Michael

“…Aim Since therapeutic hypothermia (TH) is known for its inhibitory effects on leucocyte migration and cytokine synthesis, our aim was to underline the…”
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Hemadsorption as rescue therapy for patients with multisystem organ failure in pediatric intensive care—Report of two cases reports and review of the literature by Steurer, Lisa‐Maria, Schlager, Gerald, Sadeghi, Kambis, Golej, Johann, Wiedemann, Dominik, Hermon, Michael

“…Hemadsorption via the cytokine‐adsorber CytoSorb (CytoSorbents Europe, Berlin, Germany) has successfully been used as an adjunctive method in adults, mainly…”
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Reduced TNF‐α response in preterm neonates is associated with impaired nonclassic monocyte function by Wisgrill, Lukas, Groschopf, Alina, Herndl, Elisabeth, Sadeghi, Kambis, Spittler, Andreas, Berger, Angelika, Förster‐Waldl, Elisabeth

“…Reduced functional response of nMO in low birth weight infants contributes to reduced TNF‐α response against bacterial cell wall components. Premature infants…”
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Diminished secretion and function of IL‐29 is associated with impaired IFN‐α response of neonatal plasmacytoid dendritic cells by Wisgrill, Lukas, Wessely, Isabelle, Netzl, Antonia, Pummer, Linda, Sadeghi, Kambis, Spittler, Andreas, Berger, Angelika, Förster‐Waldl, Elisabeth

“…Plasmacytoid dendritic cells (pDCs) are key players in the antiviral immune response and type III IFNs such as IL‐29 appear to play a pivotal role in pDC…”
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Pentoxifylline modulates LPS-induced hyperinflammation in monocytes of preterm infants in vitro by Schüller, Simone S, Wisgrill, Lukas, Herndl, Elisabeth, Spittler, Andreas, Förster-Waldl, Elisabeth, Sadeghi, Kambis, Kramer, Boris W, Berger, Angelika

“…Background Pentoxifylline (PTX), a methylxanthine derivate with immunomodulating properties, has been used as adjunctive treatment in severe neonatal sepsis…”
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Immaturity of Infection Control in Preterm and Term Newborns Is Associated with Impaired Toll-Like Receptor Signaling by Sadeghi, Kambis, Berger, Angelika, Langgartner, Michaela, Prusa, Andrea-Romana, Hayde, Michael, Herkner, Kurt, Pollak, Arnold, Spittler, Andreas, Förster-Waldl, Elisabeth

“…The impaired infection control related to the functional immaturity of the neonatal immune system is an important cause of infection in preterm newborns. We…”
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Endothelial cells of extremely premature infants display impaired immune response after proinflammatory stimulation by Wisgrill, Lukas, Muck, Martina, Wessely, Isabelle, Berger, Angelika, Spittler, Andreas, Förster-Waldl, Elisabeth, Sadeghi, Kambis

“…Background Endothelial cells (ECs) exert immunological functions such as production of proinflammatory cytokines/chemokines as well as facilitation of…”
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Pediatric infection and sepsis in five age subgroups: single-center registry by Hermon, Michael M., Etmayr, Theresa, Brandt, Jennifer Bettina, Sadeghi, Kambis, Burda, Gudrun, Golej, Johann

“…Summary Background Sepsis is, worldwide, one of the leading causes of death among infants and children. Over the past two decades, mortality rates have…”
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The TLR-specific adjuvants R-848 and CpG-B endorse the immunological reaction of neonatal antigen-presenting cells by Schüller, Simone, Wisgrill, Lukas, Sadeghi, Kambis, Gindl, Erich, Helmer, Hanns, Husslein, Peter, Berger, Angelika, Spittler, Andreas, Förster-Waldl, Elisabeth

“…Background: Preterm neonates display an impaired vaccine response. Neonatal antigen-presenting cells (APCs) are less effective to induce an adaptive immune…”
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The novel polyclonal Ab preparation trimodulin attenuates endotoxin-induced immune reactions in early hyperinflammation by Celia Duerr, Annica Bacher, Angelika de Martin, Monika Sachet, Kambis Sadeghi, Suzann Baumann, Corina Heinz, Andreas Spittler

“…Sepsis is a syndrome associated with excessive inflammation. Since mortality from sepsis remains high, more laboratory research is needed to provide insight…”
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MicroRNA-146: tiny player in neonatal innate immunity? by Lederhuber, Hans, Baer, Katharina, Altiok, Ipek, Sadeghi, Kambis, Herkner, Kurt R, Kasper, David C

“…Concise regulation of the Toll signaling pathway is mandatory in neonatal innate immunity. The microRNA-146 family (miR-146a/b) was recently reported to be a…”
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Monocyte toll-like receptor 4 expression and LPS-induced cytokine production increase during gestational aging by FÖRSTER-WALDL, Elisabeth, SADEGHI, Kambis, POLLAK, Arnold, SPITTLER, Andreas, TAMANDL, Dietmar, GERHOLD, Bernadette, HALLWIRTH, Ulrike, ROHRMEISTER, Klaudia, HAYDE, Michael, PRUSA, Andrea R, HERKNER, Kurt, BOLTZ-NITULESCU, George

“…Premature newborns are highly susceptible to severe bacterial infections. This is partially due to their immature innate immune system, characterized by…”
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A novel immunodeficiency syndrome associated with partial trisomy 19p13 by Seidel, Markus G, Duerr, Celia, Woutsas, Stavroula, Schwerin-Nagel, Anette, Sadeghi, Kambis, Neesen, Jürgen, Uhrig, Sabine, Santos-Valente, Elisangela, Pickl, Winfried F, Schwinger, Wolfgang, Urban, Christian, Boztug, Kaan, Förster-Waldl, Elisabeth

“…Subtelomeric deletions and duplications may cause syndromic disorders that include features of immunodeficiency. To date, no phenotype of immunological…”
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Quantitative real-time polymerase chain reaction for the accurate detection of Toxoplasma gondii in amniotic fluid by Kasper, David C, Sadeghi, Kambis, Prusa, Andrea-Romana, Reischer, Georg H, Kratochwill, Klaus, Förster-Waldl, Elisabeth, Gerstl, Nicole, Hayde, Michael, Pollak, Arnold, Herkner, Kurt R

“…Abstract Infection with Toxoplasma gondii during pregnancy is often asymptomatic and may cause severe fetal damage. A quantitative TaqMan minor groove binder…”
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Vaccination against tick-borne encephalitis virus tests specific IgG production ability in patients under immunoglobulin substitution therapy by Seidel, Markus G, Grohmann, Eva, Sadeghi, Kambis, Pollak, Arnold, Heitger, Andreas, Förster-Waldl, Elisabeth

“…Abstract To assess B-cell function in patients under immunoglobulin (IgG)-replacement therapy, the non-licensed artificial bacteriophage (ΦX174)-neo-antigen…”
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Alterations in CD44 isoforms and HAS expression in human articular chondrocytes during the de- and re-differentiation processes by Albrecht, Christian, Schlegel, Werner, Eckl, Peter, Jagersberger, Tamara, Sadeghi, Kambis, Berger, Angelika, Vécsei, Vilmos, Marlovits, Stefan

“…The purpose of this study was to investigate the expression of different CD44 and hyaluronan synthase isoforms in cartilage, their alterations during the…”
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Hemadsorption as rescue therapy for patients with multisystem organ failure in pediatric intensive care-Report of two cases reports and review of the literature by Steurer, Lisa-Maria, Schlager, Gerald, Sadeghi, Kambis, Golej, Johann, Wiedemann, Dominik, Hermon, Michael

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