Search Results - "SACCHI, A"

Mutant p53: an oncogenic transcription factor by Strano, S, Dell'Orso, S, Di Agostino, S, Fontemaggi, G, Sacchi, A, Blandino, G

“…Inactivation of tumor-suppressor genes is one of the key hallmarks of a tumor. Unlike other tumor-suppressor genes, p53 is inactivated by missense mutations in…”
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Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression by BOSSI, G, LAPI, E, STRANO, S, RINALDO, C, BLANDINO, G, SACCHI, A

“…Mutations in the TP53 tumor suppressor gene are the most frequent genetic alteration in human cancers. These alterations are mostly missense point mutations…”
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Quasars as high‐redshift standard candles by Risaliti, G., Lusso, E., Nardini, E., Bargiacchi, G., Bisogni, S., Sacchi, A., Signorini, M., Trefoloni, B.

“…In the past few years, we built a Hubble diagram of quasars up to redshift z∼7$$ z\sim 7 $$, based on the nonlinear relation between quasars' x‐ray and UV…”
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Phase-selective growth of κ- vs β-Ga2O3 and (InxGa1−x)2O3 by In-mediated metal exchange catalysis in plasma-assisted molecular beam epitaxy by Ardenghi, A., Bierwagen, O., Lähnemann, J., Luna, E., Kler, J., Falkenstein, A., Martin, M., Sacchi, A., Mazzolini, P.

“…Its large intrinsic polarization makes the metastable κ-Ga2O3 polymorph appealing for multiple applications, and the In-incorporation into both κ and β-Ga2O3…”
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Aloe barbadensis: A Plant of Nutricosmetic Interest by Laneri, S, Di Lorenzo, RM, Bernardi, A, Sacchi, A, Dini, I

“…Aloe barbadensis Miller (Aloe Vera Linne) products have long been employed in health foods and for medical purposes. It has anti-inflammatory, antifungal,…”
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Prevalence and molecular characterization of Anaplasmataceae agents in free-ranging Brazilian marsh deer ( Blastocerus dichotomus ) by Sacchi, A.B.V, Duarte, J.M.B, André, M.R, Machado, R.Z

“…Abstract Anaplasmataceae organisms comprise a group of obligate intracellular gram-negative, tick-borne bacteria that can infect both animals and humans. In…”
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Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection by Agrati, C, Castilletti, C, Casetti, R, Sacchi, A, Falasca, L, Turchi, F, Tumino, N, Bordoni, V, Cimini, E, Viola, D, Lalle, E, Bordi, L, Lanini, S, Martini, F, Nicastri, E, Petrosillo, N, Puro, V, Piacentini, M, Di Caro, A, Kobinger, G P, Zumla, A, Ippolito, G, Capobianchi, M R

“…Data on immune responses during human Ebola virus disease (EVD) are scanty, due to limitations imposed by biosafety requirements and logistics. A sustained…”
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SPEAR indicates pesticide effects in streams – Comparative use of species- and family-level biomonitoring data by Beketov, M.A., Foit, K., Schäfer, R.B., Schriever, C.A., Sacchi, A., Capri, E., Biggs, J., Wells, C., Liess, M.

“…To detect effects of pesticides on non-target freshwater organisms the Species at risk (SPEAR pesticides) bioindicator based on biological traits was…”
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Enhancement of tumor necrosis factor α antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13) by Corti, Angelo, Curnis, Flavio, Sacchi, Angelina, Borgna, Laura, Magni, Fulvio, Gasparri, Anna

“…The clinical use of tumor necrosis factor alpha (TNF) as an anticancer drug is limited to local treatments because of its dose-limiting systemic toxicity. We…”
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Physiological Evidence for a High-Affinity Cadmium Transporter Highly Expressed in a Thlaspi caerulescens Ecotype by Lombi, E., Zhao, F. J., McGrath, S. P., Young, S. D., Sacchi, G. A.

“…Uptake kinetics and translocation characteristics of cadmium and zinc are presented for two contrasting ecotypes of the Cd/Zn hyperaccumulator Thlaspi…”
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HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage by Lazzari, C, Prodosmo, A, Siepi, F, Rinaldo, C, Galli, F, Gentileschi, M, Bartolazzi, A, Costanzo, A, Sacchi, A, Guerrini, L, Soddu, S

“…Homeodomain-interacting protein kinase 2 (HIPK2) is an emerging player in cell response to genotoxic agents that senses damage intensity and contributes to the…”
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Intrahepatic Vγ9Vδ2 T-cells from HCV-infected patients show an exhausted phenotype but can inhibit HCV replication by Cimini, E., Bordoni, V., Sacchi, A., Visco-Comandini, U., Montalbano, M., Taibi, C., Casetti, R., Lalle, E., D’Offizi, G., Capobianchi, M.R., Agrati, C.

“…•The liver was enriched of Vγ9Vδ2 T-cells expressing an effector/activated phenotype, independently from HCV infection.•An enrichment of PD-1+Vγ9Vδ2 T-cells…”
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A restricted signature of miRNAs distinguishes APL blasts from normal promyelocytes by Careccia, S, Mainardi, S, Pelosi, A, Gurtner, A, Diverio, D, Riccioni, R, Testa, U, Pelosi, E, Piaggio, G, Sacchi, A, Lavorgna, S, Lo-Coco, F, Blandino, G, Levrero, M, Rizzo, M G

“…MicroRNAs (miRNAs) are small non-coding RNAs involved in the regulation of critical cell processes such as apoptosis, cell proliferation and differentiation. A…”
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Randomized controlled trial of duration of analgesia following intravenous or rectal acetaminophen after adenotonsillectomy in children by Capici, F., Ingelmo, P.M., Davidson, A., Sacchi, C.A., Milan, B., Sperti, L. Rota, Lorini, L., Fumagalli, R.

“…Doses of acetaminophen 40 mg kg−1 rectally and 15 mg kg−1 i.v. produce similar effect-site concentrations. However, the clinical effectiveness of these routes…”
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Challenges of Cardiovascular Risk Assessment in the Routine Rheumatology Outpatient Setting: An Observational Study of 110 Rheumatoid Arthritis Patients by Gossec, L., Salejan, F., Nataf, H., Nguyen, M., Gaud‐Listrat, V., Hudry, C., Breuillard, P., Dernis, E., Boumier, P., Durandin‐Truffinet, M., Fannius, J., Fechtenbaum, J., Izou‐Fouillot, M.‐A., Labatide‐Alanore, S., Lebrun, A., LeDevic, P., LeGoux, P., Sacchi, A., Salliot, C., Sparsa, L., d'André, F. Lecoq, Dougados, M.

“…Objective An annual assessment of cardiovascular (CV) risk factors in rheumatoid arthritis (RA) is recommended, but its practical modalities have not been…”
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Evaluation of collected outcome measures in axial spondyloarthritis in daily-care rheumatology settings: the experience of the RHEVER network by Che, H, Etcheto, A, Dernis, E, Nataf, H, Boumier, P, Breuillard, P, Durandin-Truffinet, M, Fechtenbaum, J, Gaud-Listrat, V, Giraud, B, Hudry, C, Labatide-Alanore, S, Le Devic, P, Le Goux, P, Lebrun, A, Maheu, E, Moura, B, Nguyen, M, Sacchi, A, Ayral, X, Blanchais, A, Neveu, S, Dougados, M, Moltó, A

“…Nowadays, the recommended measures for optimal monitoring of axial Spondyloarthritis (ax-SpA) disease activity are either BASDAI and CRP, or ASDAS-CRP…”
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HIPK2-induced p53Ser46 phosphorylation activates the KILLER DR5-mediated caspase-8 extrinsic apoptotic pathway by Pistritto, G, Puca, R, Nardinocchi, L, Sacchi, A, D'Orazi, G

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P0465 : Persistent intrahepatic Vγ9Vδ2 T-cells impairment in HCV-infected persons by Cimini, E, Bordoni, V, Visco-Comandini, U, Montalbano, M, Lionetti, R, Sacchi, A, Casetti, R, Tumino, N, Capobianchi, M.R, Martini, F, Agrati, C

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HIPK2 is involved in cell proliferation and its suppression promotes growth arrest independently of DNA damage by Iacovelli, S., Ciuffini, L., Lazzari, C., Bracaglia, G., Rinaldo, C., Prodosmo, A., Bartolazzi, A., Sacchi, A., Soddu, S.

“…Introduction/objectives:  The serine/threonine kinase homeodomain‐interacting protein kinase 2 (HIPK2) is a co‐regulator of an increasing number of…”
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Co-stimulatory molecule CD80 expression may correlate with anti-HCV treatment outcome by Sacchi, A, Agrati, C, D'Offizi, G, Vlassi, Chrysoula, Martini, F

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