Search Results - "SACCHETTI, L"
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The Pancreatitis-induced Vacuole Membrane Protein 1 Triggers Autophagy in Mammalian Cells
Published in The Journal of biological chemistry (21-12-2007)“…Autophagy is a degradation process of cytoplasmic cellular constituents, which serves as a survival mechanism in starving cells, and it is characterized by…”
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2
PEGylated helper-dependent adenoviral vector expressing human Apo A-I for gene therapy in LDLR-deficient mice
Published in Gene therapy (01-12-2013)“…Helper-dependent adenoviral (HD-Ad) vectors have great potential for gene therapy applications; however, their administration induces acute toxicity that…”
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3
Characterization and predicted role of the microRNA expression profile in amnion from obese pregnant women
Published in International Journal of Obesity (01-03-2014)“…Maternal obesity and nutrient excess in utero increase the risk of future metabolic diseases. The mechanisms underlying this process are poorly understood, but…”
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4
[LB.03.05] HELPER-DEPENDENT ADENOVIRUS-MEDIATED GENE TRANSFER OF A SECRETED LDL RECEPTOR/TRANSFERRIN CHIMERIC PROTEIN REDUCES AORTIC ATHEROSCLEROSIS IN LDL RECEPTOR-DEFICIENT MICE
Published in Journal of hypertension (01-09-2017)“…OBJECTIVE:Familial hypercholesterolemia is a genetic hyperlipidemia characterized by elevated concentration of plasma LDL cholesterol. Statins are not…”
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5
The first large population based twin study of coeliac disease
Published in Gut (01-05-2002)“…Background and aims: The genetic load in coeliac disease has hitherto been inferred from case series or anecdotally referred twin pairs. We have evaluated the…”
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6
Prognostic significance of admission levels of troponin I in patients with acute ischaemic stroke
Published in Journal of neurology, neurosurgery and psychiatry (01-01-2005)“…Objectives: Successful prediction of cardiac complications early in the course of acute ischaemic stroke could have an impact on the clinical management…”
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7
Embolization of left spermatic vein in non-obstructive azoospermic men with varicocele: role of FSH to predict the appearance of ejaculated spermatozoa after treatment
Published in Journal of endocrinological investigation (01-07-2015)“…Purpose Varicocele repair in non-obstructive azoospermia (NOA) was occasionally associated to ejaculated spermatozoa independently from clinical and laboratory…”
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8
Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum
Published in The Journal of neuroscience (16-06-2010)“…The role of brain-derived neurotrophic factor (BDNF) in emotional processes suggests an interaction with the endocannabinoid system. Here, we addressed the…”
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9
Four novel UCP3 gene variants associated with childhood obesity: effect on fatty acid oxidation and on prevention of triglyceride storage
Published in International Journal of Obesity (01-02-2012)“…Objective: The objective of the study was to look for uncoupling protein 3 ( UCP3 ) gene variants in early-onset severe childhood obesity and to determine…”
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10
A Prospective Randomized Study of Minimally Invasive Total Knee Arthroplasty Compared with Conventional Surgery
Published in Journal of bone and joint surgery. American volume (07-07-2010)“…BACKGROUND:Despite intense debate regarding whether minimally invasive techniques for total knee arthroplasty improve clinical outcomes over standard…”
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11
The absence of polymorphisms in ADRB3, UCP1, PPARγ, and ADIPOQ genes protects morbid obese patients toward insulin resistance
Published in Journal of endocrinological investigation (2012)“…Background and aims: The insulin resistance (IR) is a major metabolic impairment in severe obesity, a multifactorial disease in which the importance of the…”
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12
Polymorphism p.402Y>H in the complement factor H protein is a risk factor for age related macular degeneration in an Italian population
Published in British journal of ophthalmology (01-09-2006)“…Aims: To evaluate the complement factor H (CFH) p.402Y>H polymorphism as a risk factor in age related macular degeneration (AMD) in an Italian population…”
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13
Hemorrhagic transformation of brain infarct : Predictability in the first 5 hours from stroke onset and influence on clinical outcome
Published in Neurology (01-02-1996)“…To identify, in the first 5 hours of acute brain infarct, clinical and radiologic predictors of subsequent hemorrhagic transformation (HT), and to evaluate its…”
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14
UCP1 -3826 AG+GG genotypes, adiponectin, and leptin/adiponectin ratio in severe obesity
Published in Journal of endocrinological investigation (01-06-2009)“…Background and aims : Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are well-recognized complications of obesity. This study was…”
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15
Metabolic syndrome and ADRB3 gene polymorphism in severely obese patients from South Italy
Published in European journal of clinical nutrition (01-10-2007)“…Objective: To evaluate the prevalence of β ₃-adrenergic receptor (ADRB3) Trp64Arg polymorphism and its relationship with the metabolic syndrome in severe…”
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16
Continuous theta burst stimulation over right pars triangularis facilitates naming abilities in chronic post-stroke aphasia by enhancing phonological access
Published in Brain and language (01-05-2019)“…•rTMS has been shown to improve naming in chronic aphasia, but outcomes vary.•We explored if severity and/or type of naming impairment predicts rTMS…”
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Increased prevalence of celiac disease without gastrointestinal symptoms in adults MICA 5.1 homozygous subjects from the Campania area
Published in Digestive and liver disease (01-04-2008)“…Abstract Objectives Polymorphisms in the major histocompatibility complex class I chain-related gene A may influence its binding to the Natural Killer Cell…”
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18
Early spontaneous improvement and deterioration of ischemic stroke patients: A serial study with transcranial Doppler ultrasonography
Published in Stroke (1970) (01-06-1998)“…The purpose of our study was to investigate whether emergency transcranial Doppler (TCD) findings and their modifications over the first 48 hours are related…”
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Prevalence of Y microdeletions in azoospermic and severe oligozoospermic men in Southern Italy: Application of a rapid capillary electrophoresis method
Published in Journal of endocrinological investigation (01-03-2009)“…Male infertility is correlated with several genetic and non-genetic conditions. Microdeletions of Y chromosome are one of the most frequent genetic defects…”
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20
Deferiprone: New Insight
Published in Annals of the New York Academy of Sciences (01-01-2005)“…: Recent results from independent studies suggest that deferiprone is more cardioprotective than deferoxamine. Patients on long‐term treatment with deferiprone…”
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