Search Results - "SACCA, Paula"
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A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease
Published in Cancer research (Chicago, Ill.) (2013)“…Galectins, a family of glycan-binding proteins, influence tumor progression by modulating interactions between tumor, endothelial, stromal, and immune cells…”
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Lupane Triterpenoids and New Derivatives as Antiproliferative Agents Against Prostate Cancer Cells
Published in Anticancer research (01-07-2019)“…This study examined the potential role of natural triterpenoids lupeol, calenduladiol and heliantriol B2, and a set of 19 derivatives, as antiproliferative and…”
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Human Periprostatic Adipose Tissue: Secretome from Patients With Prostate Cancer or Benign Prostate Hyperplasia
Published in Cancer genomics & proteomics (01-01-2019)“…Background/Aim: Periprostatic adipose tissue (PPAT) directs tumour behaviour. Microenvironment secretome provides information related to its biology. This…”
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Human breast adipose tissue: characterization of factors that change during tumor progression in human breast cancer
Published in Journal of experimental & clinical cancer research (07-02-2017)“…Adipose microenvironment is involved in signaling pathways that influence breast cancer. We aim to characterize factors that are modified: 1) in tumor and non…”
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Periprostatic Adipose Tissue Microenvironment: Metabolic and Hormonal Pathways During Prostate Cancer Progression
Published in Frontiers in endocrinology (Lausanne) (13-04-2022)“…The periprostatic adipose tissue (PPAT) is a site of invasion of prostate cancer (PCa) and is part of the microenvironment. It was shown that PPAT secretes…”
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Phytochemical Study of the Genus Salpichroa (Solanaceae), Chemotaxonomic Considerations, and Biological Evaluation in Prostate and Breast Cancer Cells
Published in Chemistry & biodiversity (01-08-2017)“…Twelve Salpichroa taxa have been phytochemically analyzed. From the aerial parts of S. scandens, four known salpichrolides A, C, I, S, and an unreported…”
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Human Periprostatic Adipose Tissue: its Influence on Prostate Cancer Cells
Published in Cellular physiology and biochemistry (01-01-2012)“…Background/Aims: Adipose microenvironment is involved in signaling pathways that influence prostate cancer (PCa) progression. However, the role of human…”
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Human adipose tissue from normal and tumoral breast regulates the behavior of mammary epithelial cells
Published in Clinical & translational oncology (01-02-2013)“…Introduction Stromal-epithelial interactions mediate both breast development and breast cancer progression. In the present work, we evaluated the effects of…”
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Adipocyte differentiation influences the proliferation and migration of normal and tumoral breast epithelial cells
Published in Molecular medicine reports (01-05-2010)“…Stromal tissue regulates the development and differentiation of breast epithelial cells, with adipocytes being the main stromal cell type. The aim of the…”
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Homeostatic response under carcinogen withdrawal, heme oxygenase 1 expression and cell cycle association
Published in BMC cancer (14-12-2006)“…Chronic injury deregulates cellular homeostasis and induces a number of alterations leading to disruption of cellular processes such as cell cycle checkpoints…”
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Synthesis of encoded modified oligonucleotide libraries. Part 1: orthogonal chemistry
Published in Chemistry & biodiversity (01-04-2004)“…The basis for further development of combinatorial libraries of modified oligonucleotides tagged by a codifying sequence is discussed. The chemistry involved…”
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Comparative proteomics of soluble factors secreted by human breast adipose tissue from tumor and normal breast
Published in Oncotarget (24-07-2018)“…Tumor progression depends on the tumor-stroma interaction. In the breast, adipose tissue is the predominant stromal type. We have previously demonstrated that…”
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Synthesis and cytotoxic evaluation of four new 6E-hydroximinosteroids
Published in Steroids (01-06-2014)“…[Display omitted] •6E-hydroximinosteroids were synthesized from the corresponding ketones.•Cytotoxic activity of the compounds was evaluated against PC-3 and…”
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Role of 20-Hydroxyeicosatetraenoic Acid (20-HETE) in Androgen-Mediated Cell Viability in Prostate Cancer Cells
Published in Hormones & cancer (01-08-2017)“…20-Hydroxyeicosatetraenoic acid (20-HETE) is generated intracellularly through the ω-hydroxylation of arachidonic acid by the cytochrome P450 (in humans,…”
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Synthesis of Encoded Modified Oligonucleotide Libraries. Part 1
Published in Chemistry & biodiversity (01-04-2004)“…The basis for further development of combinatorial libraries of modified oligonucleotides tagged by a codifying sequence is discussed. The chemistry involved…”
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